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1. Failure of syndromic management due to drug-resistant Mycoplasma genitalium infection in South Africa: a case report.

Author

Maduna, Liteboho D, Laumen, Jolein GE, Radebe, Oscar, Kock, Marleen M, and Peters, Remco PH

Subjects
MYCOPLASMA, INFECTION, BACTERIAL diseases, RIBOSOMAL RNA, ANTIBIOTICS, DNA, DRUG resistance in microorganisms, MACROLIDE antibiotics, MYCOPLASMA diseases, POLYMERASE chain reaction, QUINOLONE antibacterial agents, RNA, URETHRITIS, URINATION disorders, HUMAN research subjects, HIV seronegativity, SEQUENCE analysis, PHARMACODYNAMICS
Abstract

We report a case of management failure of male urethritis syndrome due to macrolide-resistant Mycoplasma genitalium in South Africa. We detected mutations in 23S rRNA and one of the quinolone resistance-determining regions. This report confirms that drug-resistant M. genitalium infection can undermine the effectiveness of syndromic management in Africa. [ABSTRACT FROM AUTHOR]

Published
2019
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