1. Basis of HIV resistance suggests new vaccine strategy.
- Author
-
Senior, Kathryn and Senior, K
- Subjects
- *
HIV , *IMMUNE response , *SEX workers , *VACCINES , *IMMUNOLOGY , *HIV prevention , *HIV infection epidemiology , *AIDS vaccines , *CELLULAR immunity , *COMPARATIVE studies , *HIV infections , *LONGITUDINAL method , *RESEARCH methodology , *MEDICAL cooperation , *REFERENCE values , *RESEARCH , *RISK assessment , *STATISTICAL sampling , *T cells , *EVALUATION research , *DISEASE incidence , *HIV seroconversion , *HIV seronegativity , *PHARMACODYNAMICS - Abstract
Reports that a study of the immune responses in sex workers in Nairobi, Kenya, revealed that women who remain seronegative for HIV for several years mounted cytotoxic T lymphocyte responses to a different set of epitopes than those who were HIV positive. Trial of a vaccine that includes the seronegative-specific isotopes; Difficulty of developing a vaccine in Africa, because of genetic variability of the virus and the host population; Outlook for another vaccine that is being tested.
- Published
- 2001
- Full Text
- View/download PDF