1. Detection of New Delhi metallo-β-lactamase (encoded by blaNDM-1) in Acinetobacter schindleri during routine surveillance.
- Author
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McGann P, Milillo M, Clifford RJ, Snesrud E, Stevenson L, Backlund MG, Viscount HB, Quintero R, Kwak YI, Zapor MJ, Waterman PE, and Lesho EP
- Subjects
- Acinetobacter isolation & purification, Acinetobacter Infections microbiology, Afghanistan, Chromosomes, Bacterial, DNA, Bacterial chemistry, DNA, Bacterial genetics, Humans, Molecular Sequence Data, Plasmids, Real-Time Polymerase Chain Reaction, Sequence Analysis, DNA, Acinetobacter enzymology, Acinetobacter genetics, beta-Lactamases genetics
- Abstract
A carbapenem-resistant Alcaligenes faecalis strain was isolated from a surveillance swab of a service member injured in Afghanistan. The isolate was positive for bla(NDM) by real-time PCR. Species identification was reevaluated on three identification systems but was inconclusive. Genome sequencing indicated that the closest relative was Acinetobacter schindleri and that bla(NDM-1) was carried on a plasmid that shared >99% identity with one identified in an Acinetobacter lwoffii isolate. The isolate also carried a novel chromosomally encoded class D oxacillinase.
- Published
- 2013
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