1. Some of the most interesting CASP11 targets through the eyes of their authors
- Author
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Kryshtafovych, Andriy, Moult, John, Baslé, Arnaud, Burgin, Alex, Craig, Timothy K, Edwards, Robert A, Fass, Deborah, Hartmann, Marcus D, Korycinski, Mateusz, Lewis, Richard J, Lorimer, Donald, Lupas, Andrei N, Newman, Janet, Peat, Thomas S, Piepenbrink, Kurt H, Prahlad, Janani, van Raaij, Mark J, Rohwer, Forest, Segall, Anca M, Seguritan, Victor, Sundberg, Eric J, Singh, Abhimanyu K, Wilson, Mark A, and Schwede, Torsten
- Subjects
Biochemistry and Cell Biology ,Bioinformatics and Computational Biology ,Biological Sciences ,Prevention ,Bacteria ,Computational Biology ,Computer Graphics ,Crystallography ,X-Ray ,Databases ,Protein ,Humans ,International Cooperation ,Models ,Molecular ,Models ,Statistical ,Protein Folding ,Protein Interaction Domains and Motifs ,Protein Multimerization ,Protein Structure ,Secondary ,Proteins ,Sequence Homology ,Amino Acid ,Software ,Viruses ,X-ray crystallography ,NMR ,CASP ,protein structure prediction ,Mathematical Sciences ,Information and Computing Sciences ,Bioinformatics ,Biological sciences ,Mathematical sciences - Abstract
The Critical Assessment of protein Structure Prediction (CASP) experiment would not have been possible without the prediction targets provided by the experimental structural biology community. In this article, selected crystallographers providing targets for the CASP11 experiment discuss the functional and biological significance of the target proteins, highlight their most interesting structural features, and assess whether these features were correctly reproduced in the predictions submitted to CASP11. Proteins 2016; 84(Suppl 1):34-50. © 2015 The Authors. Proteins: Structure, Function, and Bioinformatics Published by Wiley Periodicals, Inc.
- Published
- 2016