Search

Your search keyword '"Li, Xu‐Yang"' showing total 2 results
Start Over Author "Li, Xu‐Yang" Topic x-ray crystallography
2 results on '"Li, Xu‐Yang"'

1. Cytotoxicity of naturally occurring rhamnofolane diterpenes from Jatropha curcas.

Author

Liu, Jie-Qing, Yang, Yuan-Feng, Li, Xu-Yang, Liu, En-Qian, Li, Zhong-Rong, Zhou, Lin, Li, Yan, and Qiu, Ming-Hua

Subjects
*CELL-mediated cytotoxicity, *DITERPENES, *JATROPHA, *PLANT roots, *STEREOCHEMISTRY, *X-ray crystallography
Abstract

Highlights: [•] Nineteen diterpenoids were identified, of which 12 were previously unknown. [•] Curcusecons A–E have unusual secorhamnofolane skeletons. [•] Among the isolates, seven compounds had cytotoxic activity. [•] The dienone system in ring B is essential for cytotoxic activity. [Copyright &y& Elsevier]

Published
2013
Full Text
View/download PDF

2. Norfriedelins A–C with Acetylcholinesterase Inhibitory Activity from Acerola Tree (Malpighia emarginata).

Author

Liu, Jie-Qing, Peng, Xing-Rong, Li, Xu-Yang, Li, Ting-Zhao, Zhang, Wei-Ming, Shi, Lei, Han, Jiang, and Qiu, Ming-Hua

Subjects
*ACETYLCHOLINESTERASE inhibitors, *ENZYME activation, *MALPIGHIA emarginata, *PLANT roots, *PLANT extracts, *X-ray crystallography
Abstract

Three novel norfriedelanes, A–C (1–3), were isolated from the branches and roots of Malpighia emarginata. Their structures and absolute configurations were determined by 1D and 2D NMR techniques and X-ray crystallographic analysis. Norfriedelin A (possessing an α-oxo-β-lactone group) and norfriedelin B (with a keto-lactone group) showed acetylcholinesterase inhibitory effects with the IC50values of 10.3 and 28.7 μM, respectively. [ABSTRACT FROM AUTHOR]

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results