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Lordsburg Playa, a dry lakebed in the Chihuahuan Desert of southwestern New Mexico (USA), is crossed by Interstate Highway 10 (I-10). Dust from the playa threatens highway safety and has caused dozens of fatal accidents. Two numerical models—the U.S. Department of Agriculture's Single-Event Wind Erosion Evaluation Program (SWEEP) and the American Meteorological Society and U.S. Environmental Protection Agency Regulatory Model (AERMOD)—were used to simulate and predict the generation and dispersion of windblown soil, dust, and PM10 from playa hotspots and estimate PM10 concentrations downwind. SWEEP simulates soil loss and particulate matter emissions from the playa surface, and AERMOD predicts the concentration of transported dust. The modeling was informed by field and laboratory data on Lordsburg Playa's properties, soil and land use/land cover databases, and weather data from meteorological stations. The integrated models predicted that dust plumes originating on the playa—including a large, highly emissive area away from the highway and a smaller, less emissive site directly upwind of the interstate—can lead to hourly average PM10 concentrations of tens, to hundreds of thousands, of micrograms per cubic meter. Modeling results were consistent with observations from webcam photos and visibility records from the meteorological sites. Lordsburg Playa sediment contains metals, as will its dust, but human exposures will be short-term and infrequent. This study was the first to successfully combine the SWEEP wind erosion model and the AERMOD air dispersion model to evaluate PM10 dispersion by wind erosion in a playa environment. With this information, land managers will be able to understand the potential levels of dust and PM10 exposure along the highway, and better manage human health and safety during conditions of blowing dust and sand at Lordsburg Playa. [ABSTRACT FROM AUTHOR]