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Your search keyword '"Beran, R. G."' showing total 8 results
Start Over Author "Beran, R. G." Topic valproic acid
8 results on '"Beran, R. G."'

1. Sodium valproate.

Author

Beran RG

Subjects
Australia, Humans, Drug Prescriptions, Epilepsy drug therapy, Valproic Acid therapeutic use
Published
1988

3. Pharmacokinetics of sodium valproate in epileptic patients: prediction of maintenance dosage by single-dose study.

Author

Schapel GJ, Beran RG, Doecke CJ, O'Reilly WJ, Reece PA, Rischbieth RH, Sansom LN, and Stanley PE

Subjects
Adolescent, Adult, Aged, Biological Availability, Child, Drug Administration Schedule, Female, Humans, Kinetics, Male, Middle Aged, Valproic Acid administration & dosage, Valproic Acid blood, Epilepsy metabolism, Valproic Acid metabolism
Published
1980
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6. Sodium valproate and hepatotoxicity in epileptics.

Author

Beran RG and Rischbieth RH

Subjects
Adolescent, Adult, Anticonvulsants adverse effects, Child, Drug Therapy, Combination, Female, Humans, Male, Middle Aged, Chemical and Drug Induced Liver Injury, Epilepsy drug therapy, Valproic Acid adverse effects
Published
1979
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7. Individualized patient assessment in the treatment of epilepsy with sodium valproate.

Author

Beran RG, Read T, Reid M, Rischbieth RH, Sansom L, Schapel GJ, and Stanley PE

Subjects
Adolescent, Adult, Chemical and Drug Induced Liver Injury, Child, Clinical Trials as Topic, Female, Fibrinogen analysis, Humans, Intelligence drug effects, Liver Function Tests, Male, Platelet Aggregation drug effects, Valproic Acid adverse effects, Epilepsy drug therapy, Valproic Acid therapeutic use
Abstract

This study records a comprehensive clinical protocol developed to assess seizure control and unwanted effects in 19 patients treated with sodium valproate (VPA). The assessment is based on six parameters individually ranked: seizure frequency, seizure duration, EEG comparisons, intellectual and cognitive function tests, sociological profile, and unwanted effects. Each parameter was ranked from one to five, and the mean was used to assess the overall patient state. Using this technique, this study assesses the therapeutic efficacy of VPA and the benefits of individualization of therapy as predicted by the use of pharmacokinetic parameters in a controlled trial.

Published
1980
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