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Purpose: The aim of this study was to evaluate the clinical performance of the ACR's Ultrasound Liver Reporting and Data System (US LI-RADS™) for detecting hepatocellular carcinoma (HCC) in patients at high risk for HCC., Methods: In this retrospective, multicenter study, 2,050 patients at high risk for HCC (1,078 men and 972 women; mean age, 57.7 years) at five sites in the United States had undergone screening liver ultrasound from January 2017 to February 2018, and US LI-RADS observation categories and visualization scores were assigned on a clinical basis. Ultrasound reports and patient records were retrospectively reviewed and follow-up imaging studies and/or pathologic reports recorded. Descriptive statistics were generated, and multivariate logistic regression analysis was used to analyze the relationship of clinical and reader-based predictors of limited visualization. Diagnostic performance data were calculated in the subset of patients with confirmatory testing., Results: The most common indications for HCC screening were cirrhosis (n = 1,054 [51.4%]), noncirrhotic hepatitis B virus infection (n = 555 [27.1%]), and noncirrhotic hepatitis C virus infection (n = 234 [11.4%]). US LI-RADS observation categories assigned were US-1 (negative) in 90.4% (n = 1,854), US-2 (subthreshold) in 4.6% (n = 95), and US-3 (positive) in 4.9% (n = 101). Visualization scores were A (no or minimal limitations) in 76.8% (n = 1,575), B (moderate limitations) in 18.9% (n = 388), and C (severe limitations) in 4.2% (n = 87). Confirmatory tests, including multiphase contrast-enhanced CT or MRI (n = 331) or histopathology (n = 18), were available for 349 patients (17.0%). The sensitivity of US LI-RADS in this subset of patients was 82.4%, specificity was 74.2%, positive predictive value was 35.3%, and negative predictive value was 96.1%., Conclusions: Approximately 90% of US LI-RADS screening examinations were negative, 5% subthreshold, and 5% positive. Visualization scores were diagnostically acceptable in the vast majority (>95%) of examinations. US LI-RADS emphasized sensitivity and negative predictive value, which are key characteristics of a screening test., (Copyright © 2019 American College of Radiology. Published by Elsevier Inc. All rights reserved.)

The loss of an estrous cycle is critical in any production system. Especially in artificial insemination programs in which the detection of estrus depends on the human factor. The detection of estrus, has been one of the limitations for the massive use of artificial insemination. Therefore, the application of estrus and ovulation synchronization methods is very important in reproductive management in cattle. The objective was to evaluate by ultrasonography two estrus synchronization protocols in beef cows (Aberdeen angus). The research was carried out at the Research and Production Center (CIP) Chuquibambilla of the National University of the Altiplano. The experiment was performed with 30 cows that were divided into two groups of 15 for the first protocol (T1-Ovsynch) and 15 animals for the second protocol (T2-CIDR-synch). The ovarian function for T1 was 50% for both the right and left ovary, while for T2 it was 75 and 25% for right and left ovary, respectively; Presence of corpus luteum (CL) was 75% of cows for T1 and 60% of cows for T2, the follicle growth rate was for T1 of 0.5 ± 0.87 mm and for T2 of 1.2 ± 0.74 mm; The maximum diameter of the ovarian follicle for TI was 8.09 ± 3.23 mm and for T2 of 10.2 ± 3.16 mm and the pregnancy rate for T1 was 33.3% and for T2 of 66.7%. In conclusion, ultrasonographic evaluation is a useful tool for evaluating estrus synchronization protocols. Real-time observation of the synchrony of the emergence of a new follicular wave (at the beginning of the treatments) and ovulation in both protocols, resulting in a higher pregnancy rate.