Herle, Moritz P., Kan, Carol, Jayaweera, Kaushalya, Adikari, Anushka, Siribaddana, Sisira, Zavos, Helena M. S., Smolkina, Milana, Sumathipala, Athula, Llewellyn, Clare, Ismail, Khalida, Hotopf, Matthew, Treasure, Janet, and Rijsdijk, Frühling
This study investigated the genetic and environmental contributions to emotional overeating (EOE) and depressive symptoms, and their covariation, in a Sri-Lankan population, using genetic model-fitting analysis. In total, 3957 twins and singletons in the Colombo Twin and Singleton Study-Phase 2 rated their EOE behaviour and depressive symptoms, which were significantly associated (men: r = 0.11, 95% confidence interval (CI) 0.06-0.16, women: r = 0.12, 95% CI 0.07-0.16). Non-shared environmental factors explained the majority of variance in men (EOE e² = 87%, 95% CI 78-95%; depressive symptoms e² = 72%, 95% CI 61-83%) and women (EOE e² = 76%, 95% CI 68-83%; depressive symptoms e² = 64%, 95% CI 55-74%). Genetic factors were more important for EOE in women (h² = 21%, 95% CI 4-32%) than men (h² = 9%, 95% CI 0-20%). Shared-environmental factors were more important for depressive symptoms in men (c² = 25%, 95% CI 10-36%) than women (c² = 9%, 95% CI 0-35%). Non-shared environmental factors explained the overlap between depressive symptoms and EOE in women but not in men. Results differed from high-income populations, highlighting the need for behavioural genetic research in global populations. [ABSTRACT FROM AUTHOR]