1. Outbreak of Tuberculosis and Multidrug-Resistant Tuberculosis, Mbuji-Mayi Central Prison, Democratic Republic of the Congo.
- Author
-
Kayomo MK, Hasker E, Aloni M, Nkuku L, Kazadi M, Kabengele T, Muteteke D, Kapita F, Lufulwabo A, Mukadi YD, Muyembe-Tamfum JJ, Ieven M, de Jong BC, and Boelaert M
- Subjects
- Adolescent, Adult, Democratic Republic of the Congo epidemiology, Demography, Female, Humans, Incidence, Male, Middle Aged, Mycobacterium tuberculosis drug effects, Prevalence, Risk Factors, Sputum microbiology, Tuberculosis microbiology, Tuberculosis, Multidrug-Resistant microbiology, Young Adult, Disease Outbreaks, Mycobacterium tuberculosis isolation & purification, Tuberculosis epidemiology, Tuberculosis, Multidrug-Resistant epidemiology
- Abstract
After an alert regarding ≈31 tuberculosis (TB) cases, 3 of which were rifampin-resistant TB cases, in Mbuji-Mayi Central Prison, Democratic Republic of the Congo, we conducted an outbreak investigation in January 2015. We analyzed sputum of presumptive TB patients by using the Xpert MTB/RIF assay. We also assessed the Mycobacterium tuberculosis isolates' drug-susceptibility patterns and risk factors for TB infection. Among a prison population of 918 inmates, 29 TB case-patients were already undergoing treatment. We found an additional 475 presumptive TB case-patients and confirmed TB in 170 of them. In March 2015, the prevalence rate of confirmed TB was 21.7% (199/918 inmates). We detected an additional 14 cases of rifampin-resistant TB and initiated treatment in all 14 of these case-patients. Overcrowded living conditions and poor nutrition appeared to be the driving factors behind the high TB incidence in this prison.
- Published
- 2018
- Full Text
- View/download PDF