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1. Control of tubulin gene expression during metacyclogenesis of Trypanosoma cruzi.

Author

Rondinelli E, de Moura-Neto RS, Silva R, de Almeida Soares CM, Carvalho JF, and Torres de Castro F

Subjects
Animals, Cell Division, DNA, Recombinant, Gene Expression Regulation, Nucleic Acid Hybridization, RNA, Messenger genetics, Trypanosoma cruzi cytology, Trypanosoma cruzi genetics, Tubulin genetics
Abstract

During differentiation of the dividing epimastigote to the non-dividing metacyclic trypomastigote form of the parasitic protozoan Trypanosoma cruzi there is a marked reduction in the rate of synthesis of the major proteins alpha- and beta-tubulin. Our results indicate that the control of synthesis of these proteins during the differentiation event is exerted at the level of alpha- and beta-tubulin mRNA accumulation.

Published
1986
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