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Background: A live attenuated yellow fever (YF) vaccination is required of all travellers visiting countries where YF virus is endemic. Although the risk of serious adverse events (AEs) after YF vaccination is known to be greater in elderly people than in younger people, information about other AEs among elderly travellers is lacking.Methods: A prospective observational questionnaire study was conducted to investigate the occurrence of AEs after YF vaccination in travellers who attended a designated YF vaccination centre in Tokyo, Japan, from 1 November 2011 to 31 October 2012. A questionnaire enquiring about any AEs experienced in the 2 weeks following YF vaccination was distributed to all vaccinees enrolled in this study, and responses were collected subsequently by mail or phone. For child vaccinees, their parents were allowed to respond in their stead.Results: Of the 1298 vaccinees who received the YF vaccine, 1044 (80.4%) were enrolled in the present study and 666 (63.8%) responded to the questionnaire. Of these 666 respondents, 370 (55.6%) reported AEs, of which 258 (38.7%) were systemic and 230 (34.5%) were local. No severe AEs associated with YF vaccination were reported. Elderly vaccinees (aged ≥60 years) reported fewer total AEs than those aged <60 years (42.9% vs 60.3%;P < 0.001).Conclusion: Our study showed that fewer general AEs after yellow vaccination reported among elderly vaccinees than among non-elderly vaccinees. These results could provide supplementary information for judging the adaptation of vaccination in elderly travellers. [ABSTRACT FROM AUTHOR]

Dengue virus ( DENV) infection is a major health threat for travelers. We describe here a case of dengue virus serotype-3 ( DENV-3) infection in a traveler returning to Japan from the Republic of Benin. The isolated DENV-3 genotype 3 strain exhibited high sequence similarity to those from neighboring regions. [ABSTRACT FROM AUTHOR]

If necessary, free vaccinations for those men with low antibody Antibody prevalence rates to>85% by July 2020 when Tokyo Antibody testing and vaccinations need to be improved. Vaccine-Preventable Diseases: Status of Antibody Prevalence for. [Extracted from the article]

In Japan, YF vaccine (YF-VAX) is the only licensed vaccine, Vaccines/yellow-fever-vaccine-information/). The Sanofi Pasteur-manufactured YF vaccine from France mar- Recipientsof fractional-dose YF vaccine should be. [Extracted from the article]