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1. Emerging diagnostic challenges and characteristics of simian betaretrovirus infections in captive macaque colonies

Author

Yee, JoAnn L, Grant, Richard, Van Rompay, Koen K, Kuller, LaRene, Carpenter, Amanda, Watanabe, Robin, Huebner, Rebeca, Agricola, Brian, Smedley, Jeremy, and Roberts, Jeffrey A

Subjects
Veterinary Sciences, Agricultural, Veterinary and Food Sciences, HIV/AIDS, Infectious Diseases, Infection, Good Health and Well Being, Animals, Betaretrovirus, Macaca, Monkey Diseases, Retroviridae Infections, endogenous virus, PCR, serology, transfusion, Zoology, Virology, Veterinary sciences
Abstract

To better understand Simian betaretrovirus (SRV) seropositivity in virus-negative macaques, we transfused blood from SRV-infected or suspect donors into immunosuppressed naive recipients. Our results do not support typical SRV1-5 infection as the cause, but provide evidence for several possibilities including serological artifact, new/different SRV, or an endogenous virus.

Published
2017

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