1. Hypogastrinemia and esophageal atresia.
- Author
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Davenport M, Mughal M, McCloy RF, and Doig CM
- Subjects
- Esophageal Atresia complications, Esophageal Atresia surgery, Gastrins deficiency, Gestational Age, Humans, Infant, Newborn, Reference Values, Tracheoesophageal Fistula complications, Tracheoesophageal Fistula surgery, Birth Weight, Esophageal Atresia blood, Gastrins blood, Infant, Low Birth Weight blood, Tracheoesophageal Fistula blood
- Abstract
To investigate extraesophageal anomalies in infants with esophageal atresia, preoperative plasma gastrin was measured in 12 infants. The median plasma gastrin was 32 ng/L (interquartile range, 24 to 44). There was significant correlation with birth weight (rs = .73, P less than .05) and gestational age (rs = .74, P less than .05). Within this group 9 infants of greater than 36 weeks' gestation were matched to a group of 20 control infants without esophageal atresia. Infants with esophageal atresia had a significantly lower median plasma gastrin (38 ng/L v 55 ng/L, P less than .05). This may indicate preexisting vagal abnormalities in esophageal atresia unrelated to surgical intervention.
- Published
- 1992
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