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Your search keyword '"Eerenstein, Simone E. J."' showing total 5 results
Start Over Author "Eerenstein, Simone E. J." Topic total laryngectomy
5 results on '"Eerenstein, Simone E. J."'

4. A prospective randomized multicenter clinical trial of the Provox2 and Groningen Ultra Low Resistance voice prostheses in the rehabilitation of post-laryngectomy patients: a lifetime and preference study

Author

Harms, Kim, Post, Wendy J., van de Laan, Klaas T., van den Hoogen, Frank J. A., Eerenstein, Simone E. J., van der Laan, Bernard F. A. M., Erenstein, S.E., Otolaryngology / Head & Neck Surgery, CCA - Quality of life, Nieuwenhuis Institute (Pedagogical and Educational Sciences), Faculteit Medische Wetenschappen/UMCG, Damage and Repair in Cancer Development and Cancer Treatment (DARE), and Man, Biomaterials and Microbes (MBM)

Subjects
Male, medicine.medical_specialty, Cancer Research, Patient Dropouts, CARCINOMA, TOTAL LARYNGECTOMY, medicine.medical_treatment, Groningen Ultra Low Resistance, Laryngectomy, Aetiology, screening and detection [ONCOL 5], Prosthesis Design, Prosthesis, Preference, Internal medicine, Surveys and Questionnaires, Perception and Action [DCN 1], medicine, Humans, Prospective Studies, Laryngeal Neoplasms, RESTORATION, Netherlands, Rehabilitation, business.industry, Repeated measures design, Surgery, Prosthesis Failure, Clinical trial, Equipment Failure Analysis, Oncology, Patient Satisfaction, High phonating resistance, Provox2, EXPERIENCE, Female, Tracheo-esophageal shunt prosthesis, Oral Surgery, Low resistance, business, Larynx, Artificial, Lifetime
Abstract

To prospectively study patients' preference for and the lifetime of the Groningen Ultra Low Resistance (GULR) and Provox2 tracheo-esophageal shunt prosthesis (TESP, plural TESPs) in post-laryngectomy patients. Eighty post-laryngectomy patients were included in 4 oncological centers in the Netherlands. We used a repeated measures design study with 4 randomized groups in a partial cross-over design using 3 consecutive TESPs (3 intervals) in different orders. (Group 1: GULR-GULR-GULR; Group 2: GULR-GULR-Provox2; Group 3: Provox2-Provox2-GULR; and Group 4: Provox2-Provox2-Provox2). Replacement dates and reasons for replacement were monitored with questionnaires as were patients' preferences for GULR or Provox2. A great variability of lifetime within and between groups was seen. Mean lifetimes found (all groups and intervals added) were 106.2 and 102.7 days, and median lifetimes were 76 and 65 days for GULR and Provox2, respectively. Lifetime showed no significant differences between groups, intervals, and TESP types. Many patients dropped out due to reasons having to do with GULR-characteristics (n = 21). The main dropout reason was "high phonating resistance (HPR)" (57.1%). Only 10 patients preferred GULR. A significantly larger number of patients (n = 39, 79.6%) preferred Provox2 either by choice or by dropping out due to GULR-characteristics (P

Published
2011

5. Effectiveness and cost-utility of a guided self-help exercise program for patients treated with total laryngectomy: protocol of a multi-center randomized controlled trial.

Author

Jansen, Femke, Cnossen, Ingrid C., Eerenstein, Simone E. J., Coupé, Veerle M. H., Witte, Birgit I., van Uden-Kraan, Cornelia F., Doornaert, Patricia, Braunius, Weibel W., De Bree, Remco, Hardillo, José A. U., Honings, Jimmie, Halmos, György B., Leemans, C. René, Leeuw, Irma M. Verdonck-de, and Verdonck-de Leeuw, Irma M

Subjects
LARYNGECTOMY, PHYSICAL training & conditioning, SHOULDER exercises, LARYNGECTOMEES, RANDOMIZED controlled trials, EXERCISE therapy, COMPARATIVE studies, COST effectiveness, DEGLUTITION disorders, EXPERIMENTAL design, LONGITUDINAL method, RESEARCH methodology, MEDICAL cooperation, PATIENT education, QUALITY of life, QUESTIONNAIRES, RESEARCH, HEALTH self-care, SPEECH disorders, EVALUATION research, TREATMENT effectiveness, ECONOMICS
Abstract

Background: Total laryngectomy with or without adjuvant (chemo)radiation often induces speech, swallowing and neck and shoulder problems. Speech, swallowing and shoulder exercises may prevent or diminish these problems. The aim of the present paper is to describe the study, which is designed to investigate the effectiveness and cost-utility of a guided self-help exercise program built into the application "In Tune without Cords" among patients treated with total laryngectomy.Methods/design: Patients, up to 5 years earlier treated with total laryngectomy with or without (chemo)radiation will be recruited for participation in this study. Patients willing to participate will be randomized to the intervention or control group (1:1). Patients in the intervention group will be provided access to a guided self-help exercise program and a self-care education program built into the application "In Tune without Cords". Patients in the control group will only be provided access to the self-care education program. The primary outcome is the difference in swallowing quality (SWAL-QOL) between the intervention and control group. Secondary outcome measures address speech problems (SHI), shoulder disability (SDQ), quality of life (EORTC QLQ-C30, QLQ-H&N35 and EQ-5D), direct and indirect costs (adjusted iMCQ and iPCQ measures) and self-management (PAM). Patients will be asked to complete these outcome measures at baseline, immediately after the intervention or control period (i.e. at 3 months follow-up) and at 6 months follow-up.Discussion: This randomized controlled trial will provide knowledge on the effectiveness of a guided self-help exercise program for patients treated with total laryngectomy. In addition, information on the value for money of such an exercise program will be provided. If this guided self-help program is (cost)effective for patients treated with total laryngectomy, the next step will be to implement this exercise program in current clinical practice.Trial Registration: NTR5255 Protocol version 4 date September 2015. [ABSTRACT FROM AUTHOR]

Published
2016
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