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The aim of the study is to determine the optimal properties of toothpaste for patients receiving occlusal splint therapy. The study comprised 50 people with full dentition (21 male and 29 female) divided into two groups. The main group included 25 individuals receiving occlusal splint therapy while 25 people who did not use splints were recruited as controls. Each group was further divided into two subgroups according to toothpaste used for regular oral hygiene. Examinations were performed after 14, 30 and 90 days using hygienic indices of NCI-C and Turesky and PMA gingival index. The combined effect of toothpaste was estimated by the change in the volume and acidity of saliva. The results suggest a better level of hygiene in the group I, which used toothpaste with sodium bicarbonate and silica.

The purpose of the study was to assess the impact of toothpastes containing hydroxyapatite and fluoride on enamel caries resistance and remineralization rate. Study groups comprised 160 patients divided in 2 groups of 80 patients: 40 - at the age of 15-17 and 40 at the age of 18-25 who have been using toothpastes with hydroxyapatite and fluoride during 1 year. The plaque determination was carried out with the use of OHI-S and Turesky indexes. Litmus test pieces were used to determine oral fluid pH. The clinical determination of enamel remineralization rate, dynamics of acid resistance of enamel were carried out. Oral hygiene at baseline examination was poor in both groups. After oral hygiene training, there was a tendency towards indexes decrease more pronounced in the 18-25 age group regardless of the composition of the toothpastes used. Mean baseline oral fluid pH in the observation group was 6.5±0.4, in the comparison group - 6.8±0.4. By the end of the trial there was a tendency towards the increase of the oral fluid pH, which were 7.3±0.3 and 7.7±0.3, respectively. The enamel acid resistance of the patients of the observation group was significantly higher (p>0.05) compared with the group of patients using fluoride toothpaste, as well as the proportion of patients in whom the enamel recovery occurred within 24 hours (47.5% vs. 22.5%, respectively).

The aim of the study was to evaluate the efficacy of toothpaste «Apadent Total Care» containing nanocalciumhydroxyapatite and its influence on caries resistance of tooth enamel and teeth sensitivity. The study involved 30 people: 15 patients aged 17-25 years and 15 aged 35-44 years. Study participants used «Apadent Total Care» toothpaste with nanocalciumhydroxyapatite. To evaluate the effectiveness of toothpastes clinical assessment of enamel remineralization rate was carried out, as well as the dynamics of enamel acid resistance and teeth sensitivity (Shiff index). Clinical evaluation of tooth enamel before the procedure and after 3 months of use of toothpaste with nanohydroxyapatite showed the improvement of all indices. Time for complete remineralisation of enamel in both groups did not exceed 3 days. Acid resistance of tooth enamel increased by 1.65 in group I and 1,75 in group II. The Schiff index after 3 months of using «Apadent» toothpaste also decreased in both groups.

For patients with coronary heart disease oral hygiene and treatment of oral mucosa inflammatory changes and periodontal disease are of vital importance. Dental status assessment in 110 patients hospitalized in cardiology department revealed that they all suffered from periodontal disease, diseases of teeth and oral mucosa. In 100% of cases it was necessary to improve oral hygiene. Inclusion in everyday hygienic oral care of toothpaste and mouthwash Bluem reduced the severity of inflammatory changes and improved the hygienic condition of the oral cavity.

There are a number of reasons that lead to inadequate salivation or complete cessation of salivation. Among others, one of the main can be systemic diseases like Sjögren's syndrome, and the use of medication and radiation therapy. When affected by Xerostomia, oral mucosa requires constant moisturizing. Medicaments stimulating saliva secretion and moisturizers for oral mucosa alleviate symptoms in most of the cases. LABORATORIOS KIN S.A. is a Spanish company offering a mouth moisturizing products' line, among others, KIN HIDRAT toothpaste and KIN HIDRAT spray with a formulation close to natural saliva.