1. Radiologically Occult Invasive Pulmonary Aspergillosis in a Patient With Liver Transplant.
- Author
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Esendagli D, Serifoglu I, Savas Bozbas S, Tepeoglu M, Akcay S, and Haberal M
- Subjects
- Acute Kidney Injury diagnosis, Acute Kidney Injury etiology, Acute Kidney Injury therapy, Antifungal Agents therapeutic use, Bronchoscopy, Humans, Immunocompromised Host, Immunosuppressive Agents adverse effects, Invasive Pulmonary Aspergillosis drug therapy, Invasive Pulmonary Aspergillosis microbiology, Male, Middle Aged, Predictive Value of Tests, Renal Dialysis adverse effects, Risk Factors, Treatment Outcome, Invasive Pulmonary Aspergillosis diagnostic imaging, Liver Transplantation adverse effects, Tomography, X-Ray Computed
- Abstract
Invasive pulmonary aspergillosis is an infection seen in patients receiving intensive immunosuppressive regimens, such as transplant recipients. Some risk factors that increase the incidence of infection have been determined, and patients defined as having high risk are recommended to take antifungal prophylaxis and be monitored closely. Here, we present a liver transplant patient with mild respiratory symptoms and a normal chest radiography on day 26 posttransplant. However, he had acute renal failure and underwent hemodialysis, which are both defined to increase significantly the risk of aspergillosis. Although the radiographic scan was initially normal, thorax tomography and later bronchoscopy showed findings compatible with pulmonary aspergillosis, and the patient was started on antifungal treatment. The nonspecific mild symptoms and an initial normal radiology can make diagnosis of invasive fungal infections difficult; thus caution and close follow-up of high-risk patients should be performed.
- Published
- 2018
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