Search

Your search keyword '"Masakazu Wakayama"' showing total 5 results
Start Over Author "Masakazu Wakayama" Topic toluene
5 results on '"Masakazu Wakayama"'

1. Synthesis of enediyne model compounds producing toluene diradicals possessing a highly radical character via enyne–allene intermediates

Author

Hisao Nemoto, Masayuki Shibuya, Akira Shigenaga, Ichiro Suzuki, and Masakazu Wakayama

Subjects
Enyne, Chemistry, Allene, Radical, Organic Chemistry, Ionic bonding, Biochemistry, Combinatorial chemistry, Toluene, chemistry.chemical_compound, Drug Discovery, Enediyne, Molecule, Benzene
Abstract

Development of enediyne model compounds that produce dehydrotoluene diradicals under acidic media is described. The ionic character of the diradicals is shown to be avoided by the electron-withdrawing groups in the molecules both in benzene and MeOH.

Published
2000

2. Pyridoxal-mediated cycloaromatization of an enediyne model system

Author

Masakazu Wakayama, Hisao Nemoto, and Masayuki Shibuya

Subjects
chemistry.chemical_classification, chemistry.chemical_compound, Enzyme, chemistry, Stereochemistry, Organic Chemistry, Drug Discovery, Enediyne, Substrate (chemistry), Model system, Biochemistry, Toluene, Pyridoxal
Abstract

The acyclic enediyne possessing an aminomethyl group was designed and synthesized as a potential substrate for pyridoxal-dependent enzymes. Compound 2 was shown to give cycloaromatized products by the reaction with pyridoxal or isonicotinaldehyde via the toluene biradical intermediate.

Published
1996

3. Cycloaromatization of enediyne model compounds via a reaction cascade triggered by hydrolysis of the α-alkynylmalonates

Author

Katsuya Ishigaki, Tadaaki Kawakami, Yoshimitsu Naoe, Yoshimitsu Nagao, Masakazu Wakayama, Masayuki Shibuya, Hisashi Shimizu, and Hisao Nemoto

Subjects
Quenching (fluorescence), Chemistry, Stereochemistry, Organic Chemistry, Disproportionation, Ester hydrolysis, Photochemistry, Biochemistry, Toluene, Hydrolysis, chemistry.chemical_compound, Deuterium, Cascade, Drug Discovery, Enediyne
Abstract

Diethyl α-methoxy-α-alkynylmalotate derivatives of cis -enediynes were synthesized and they produced toluenebiradicals via the reaction cascade triggered by ester hydrolysis. Deuterium labeling studies suggested that the reaction involved the self quenching process by fairly fast disproportionation of toluene biradicals producing zwitterionic species.

Published
1996

4. ChemInform Abstract: Cycloaromatization of Enediyne Model Compounds via a Reaction Cascade Triggered by Hydrolysis of the α-Alkynylmalonates

Author

Masayuki Shibuya, Hisashi Shimizu, Katsuya Ishigaki, Yoshimitsu Nagao, Masakazu Wakayama, Hisao Nemoto, Tadaaki Kawakami, and Yoshimitsu Naoe

Subjects
Hydrolysis, chemistry.chemical_compound, Quenching (fluorescence), Deuterium, Chemistry, Cascade, Enediyne, Disproportionation, Ester hydrolysis, General Medicine, Photochemistry, Toluene
Abstract

Diethyl α-methoxy-α-alkynylmalotate derivatives of cis -enediynes were synthesized and they produced toluenebiradicals via the reaction cascade triggered by ester hydrolysis. Deuterium labeling studies suggested that the reaction involved the self quenching process by fairly fast disproportionation of toluene biradicals producing zwitterionic species.

Published
2010

5. ChemInform Abstract: Synthesis of Enediyne Model Compounds Producing Toluene Diradicals Possessing a Highly Radical Character via Enyne-Allene Intermediates

Author

Masayuki Shibuya, Ichiro Suzuki, Hisao Nemoto, Akira Shigenaga, and Masakazu Wakayama

Subjects
chemistry.chemical_compound, Character (mathematics), chemistry, Enyne, Allene, Enediyne, Organic chemistry, Molecule, Ionic bonding, General Medicine, Benzene, Toluene, Combinatorial chemistry
Abstract

Development of enediyne model compounds that produce dehydrotoluene diradicals under acidic media is described. The ionic character of the diradicals is shown to be avoided by the electron-withdrawing groups in the molecules both in benzene and MeOH.

Published
2001

Catalog

Books, media, physical & digital resources
See catalog results