1. The utility of collaborative biobanks for cardiovascular research.
- Author
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Shalhoub J, Davies KJ, Hasan N, Thapar A, Sharma P, and Davies AH
- Subjects
- Biomedical Research ethics, Genome-Wide Association Study, Humans, Organizational Objectives, Risk Assessment, Risk Factors, Systems Biology, Tissue Banks ethics, Atherosclerosis diagnosis, Atherosclerosis ethnology, Atherosclerosis etiology, Atherosclerosis genetics, Biomedical Research organization & administration, Cooperative Behavior, Interdisciplinary Communication, Tissue Banks organization & administration
- Abstract
Differences between animal and human atherosclerosis have led to the requirement for clinical data, imaging information and biological material from large numbers of patients and healthy persons. Where such "biobanks" exist, they have been fruitful sources for genomewide association, diagnostic accuracy, ethnicity, and risk stratification cohort studies. In addition once established, they attract funding for future projects. Biobanks require a network of medical contributors, secure storage facilities, bioinformatics expertise, database managers, and ethical working practices to function optimally. There is the opportunity for collaboration between individual biobanks to further amplify the advantages afforded.
- Published
- 2012
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