1. High-sensitivity and label-free identification of a transgenic genome using a terahertz meta-biosensor.
- Author
-
Yang Y, Xu D, and Zhang W
- Subjects
- Refractometry methods, Biosensing Techniques, DNA, Plant genetics, Genome, Plant, Solanum lycopersicum genetics, Plants, Genetically Modified genetics, Terahertz Spectroscopy
- Abstract
A high-sensitivity and label-free method for identifying a transgenic plant genome is highly desirable in plant biotechnology. Here, we present a terahertz (THz) metamaterial (MM)-based biosensor that comprises a planar array of gold split-ring (SR) resonators capable of sensing a considerable shift in the resonance frequency due to the change of the dielectric environment on the MM chip. The meta-sensor is employed to detect transgenic tomato genome DNAs by THz time-domain spectroscopy. The experimental results were confirmed by finite-element modeling through varying the thickness and dielectric constant of the DNA overlayer. Consequently, high-efficiency and label-free discrimination between the wild-type and transgenic genome DNA was achieved.
- Published
- 2018
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