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Ten development tendencies and strategies of acupuncture in the 21st century were discussed in the paper. Legislation is the trend in the development of internationalization of Chines medicine and acupuncture. The reform in the theory of Chinese Medicine, Herbal Formulas, and Clinical practice is the trend in the internationalization of Traditional Chinese Medicine. Standardization of Chinese Medicine and acupuncture will seek common ground while reserving differences. There will be more and more experienced TCM practitioners overseas The integration and expansion of Overseas TCM institutions. Protection of Chinese Medicine and Acupuncture intellectual property will be taken seriously. Diverse development of oversea TCM acupuncture education. The non-substitutability of the inheritance of TCM acupuncture manipulation techniques. The internet, digital media technologies, and risk investment will promote the globalization process of TCM and acupuncture. China as the cradle of Acupuncture and Chinese Medicine boosts the globalization process of TCM acupuncture. [ABSTRACT FROM AUTHOR]