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It has been shown that CorTemp TM telemetric pills (CTTPs) provide valid measures of rectal temperature when used as suppositories. While encapsulated into a condom linked to a thread, CTTPs can be inserted in and extracted from the rectum and be reused. The validity and reliability of the CTTP throughout repeated use remains to be demonstrated. Three CTTPs were compared to a YSI 401 wired rectal probe inside a circulating water bath (temperatures varying from 36.5 to 39.4 °C) during 50 h of intermittent use. Each CTTP underwent 20 trials comprising 6 protocols of varying duration: 6 · 1 h, 5 · 2 h, 4 · 3 h, 3 · 4 h and 2 · 5 h. All CTTPs were washed, switched off and disinfected after each trial to reproduce real-life use. Acceptable agreement between sensors was taken as a mean bias within ±0.27 °C. None of the pills showed signs of deterioration following 50 h of reuse. As for relative validity, where all CTTPs showed robust coefficients of determination ranging from 0.98 to 0.99, absolute validity was excellent with each CTTP showing mean biases and typical errors of the estimate (TEE) within ±0.27 °C. Comparisons between the first and last trial each CTTP underwent resulted in means biases and TEEs within ±0.27 °C and coefficients of determination ranging from 0.97 to 0.99, which indicates strong absolute and relative reliability. The present results show that CTTPs can provide valid and reliable measurements of temperature when reused up to 50 h., (Copyright © 2020 Elsevier Ltd. All rights reserved.)

Wireless measurement of rectal temperature during exercise may circumvent some limitations associated with the use of a conventional wired probe. We determined, for the first time, whether temperatures provided in vivo by wireless ingestible thermometric telemetric pills and a rectal probe compare favorably under conditions producing slow and rapid increases and decreases in rectal temperature. While wearing a rectal probe linked to a wireless ingestible thermometric telemetric pill, 13 participants completed the following phases: 1) 30 min sitting; 2) 45 min passive heat exposure (40-42 °C); 3) 45 min sitting while ingesting 7.5 g of ice slurry · kg body mass -1 ; 4) running exercise (38 °C) at 68% V˙O 2max until a 39.5 °C increase in rectal probe temperature and; 5) cold-water (10 °C) immersion until a 1.5 °C decrease in rectal probe temperature. Acceptable differences between devices were taken as ≤ 0.3 °C. Mean differences within phases were all < 0.3 °C, whereas 95% limits of agreement ranged from ±0.2 °C to ±0.4 °C, coefficient of variations from ±0.3% to ±0.6% and typical error of measurements from ±0.1 °C to ±0.2°. Of the 14881 rectal temperature values measured over the experiment with the wireless ingestible thermometric telemetric pills and rectal probe, 91% of the differences between devices were found to be ≤ 0.3 °C. Results suggest that rectal temperatures provided by a wireless ingestible thermometric telemetric pill used as a suppository agree with those of a conventional wired probe. Hence, rectal temperature can reliably be measured using a wireless ingestible thermometric telemetric pill as a suppository., (Copyright © 2019 Elsevier Ltd. All rights reserved.)

Gastrointestinal temperature (Tgint) measurement with a telemetric pill (TP) is increasingly used in exercise science. Contact of cool water with a TP invalidates Tgint assessment. However, what effect a heat sink created in the proximity of a TP may have on the assessment of Tgint remains unknown. We examined the impact of an ice slurry-induced heat sink on Tgint and rectal temperature (Trec) following exercise. After 20 min of seating (20-22 °C, 25-40% relative humidity (RH)), 11 men completed two intersperse exercise periods (31-32 °C, 35% RH) at 75-80% of estimated maximal heart rate until a Trec increase of 1 °C above baseline level. Following the first exercise period, participants were seated for 45 min and ingested 7.5 g·kg-1 of thermoneutral water, whereas, following the second period, they ingested 7.5 g·kg-1 of ice slurry. Both Tgint and Trec were measured continuously. The TPs were swallowed 10 h prior to the experiments. A bias -0.27 °C was taken as an indication that Tgint and Trec provided similar core temperature indices. Mean biases and 95% limits of agreement during passive sitting, first exercise, water ingestion, second exercise, and ice slurry ingestion periods were 0.16 ± 0.53, 0.13 ± 0.41, 0.21 ± 0.70, 0.17 ± 0.50, and 0.18 ± 0.66 °C, respectively. The rates of decrease in Tgint and Trec did not differ between the water and ice slurry ingestion periods. Our results indicate that ice slurry ingestion following exercise does not impact TP-derived assessment of Tgint compared with Trec. [ABSTRACT FROM AUTHOR]