The Kylindra cemetery on Astypalaia in the Dodecanese, in use 750 BC to 1st century AD, contains a unique skeletal collection. Over 2,400 infant inhumations, each buried in its own clay pot, have been uncovered so far. The skeletal material from each burial is embedded within a ball of accreted earth and since 2001, some 850 infant remains have been recovered and conserved. Most of these died perinatally, but some were very premature babies and some appear to have survived for several months after birth. A study to estimate ages at death of 277 teeth from 107 infants, using microstructural growth markers, is currently underway. One immediate objective is to help resolve the enigma of why such an unusually large number of infants were interred on such a remote Aegean island. Longer term objectives are to reconstruct the sequences of development of the different deciduous tooth types, providing new standards of growth for long bones, the skull and the dentition. This paper presents an interim report on the findings from the histological study, which has analysed 68 teeth from 36 individuals so far. Five of the 36 infants survived birth, three dying within the first 3 weeks of life and the other two surviving for about 3 months. Average appositional growth rates were found to be 3.6 μm/day, and initial mineralisation was found to be well below the figures in Sunderland and coworkers' study in 1987. Copyright © 2009 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]