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Your search keyword '"Liquid chromatography–mass spectrometry"' showing total 2 results
Start Over Descriptor "Liquid chromatography–mass spectrometry" Topic tandem mass spectrometry Region california
2 results on '"Liquid chromatography–mass spectrometry"'

1. Determination of Heterocyclic Aromatic Amines (HAAs) in Urban Particulate Standard Reference Material and Wildfire-Influenced Particulate Matter by High-Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS).

Author

Miller-Schulze, Justin P., Dal Porto, Rachael, Fagundes, Ashley, Oanh Pham, Kim, Olson, Michael, and Schauer, James J.

Subjects
*PARTICULATE matter, *AROMATIC amines, *REFERENCE sources, *HIGH performance liquid chromatography, *TANDEM mass spectrometry, *LIQUID chromatography-mass spectrometry, *QUADRUPOLE ion trap mass spectrometry
Abstract

Heterocyclic aromatic amines (HAAs) are carcinogenic and mutagenic compounds formed by the cooking of meat and combustion of biomass. There are relatively few data on HAAs in atmospheric particulate matter (PM). We developed an analytical method using high performance liquid chromatography – tandem mass spectrometry (tandem quadrupole, HPLC-MS/MS(QqQ)) to analyze PM samples for 12 HAAs. We applied this method to an urban air standard reference material and wildfire-impacted PM2.5 from the 2018 wildfire season in Northern California. The PM sample matrix adversely impacted the MS/MS response, with high levels of ion suppression for sample masses >4 mg and higher ion suppression in wildfire-impacted particulate matter compared with the standard reference material. Despite detection limits at the low ng level, no HAAs were detected in the standard reference material, but β-carboline norharman (0.34 ng/m3) was detected in one wildfire sample. [ABSTRACT FROM AUTHOR]

Published
2022
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2. Novel LC-MS/MS Method with a Dual ESI and APCI Ion Source for Analysis of California-Regulated Pesticides and Mycotoxins in Medium-Chain Triglyceride (MCT) Oil Cannabis Tinctures.

Author

Dalmia, Avinash, Johnson, Charles, Hariri, Saba, Jalali, Jacob, Cudjoe, Erasmus, Kingstad, Joey, and Feng Qin

Subjects
*MYCOTOXINS, *ION analysis, *LIQUID chromatography-mass spectrometry, *ION sources, *PESTICIDES, *TANDEM mass spectrometry, *CANNABIS (Genus), *SOLVENT extraction
Abstract

A novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method with a dual electrospray ionization (ESI) and atmospheric-pressure chemical ionization (APCI) source was developed for analysis of 66 pesticides and 5 mycotoxins regulated by the State of California in medium-chain triglyceride (MCT) oil cannabis tinctures. The limits of quantitation (LOQs) of all of the pesticides and mycotoxins were well below California state action limits of these analytes in cannabis-based non-inhalable or edible products. A total of 62 (out of 66) pesticides and 5 mycotoxins were analyzed using LC-MS/MS with an ESI source, and the remaining 4 pesticides were determined using LC-MS/MS with an APCI source. A simple, fast, and cheap acetonitrile solvent extraction method was used for sample preparation to get good recovery and achieve high throughput for this analysis. For late-eluted analytes, a number of internal standards were used to compensate for ion suppression effects from the hydrophobic matrix. [ABSTRACT FROM AUTHOR]

Published
2020

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