1. Adverse childhood experiences, risk of opioid misuse and its pathway among students at a public university.
- Author
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Fortson, Kennicia, Rajbhandari-Thapa, Janani, Ingels, Justin, Thapa, Kiran, and Dube, Shanta R.
- Subjects
SUBSTANCE abuse risk factors ,ADVERSE childhood experiences ,PSYCHOLOGY of college students ,CONFIDENCE intervals ,CROSS-sectional method ,MULTIPLE regression analysis ,MEDICAL screening ,RISK assessment ,SURVEYS ,COMPARATIVE studies ,QUESTIONNAIRES ,DESCRIPTIVE statistics ,DRUGS ,OPIOID analgesics ,PATH analysis (Statistics) ,DOSE-response relationship in biochemistry - Abstract
Objective: We examine role of ACEs and pathways to risk of opioid misuse among young adults. Participants and Methods: A cross-sectional survey of validated measures of ACEs, risk of opioid misuse, and health conditions with a sample of 1,402 students from a large public university followed by multivariate logistic regression and pathway analysis. Results: Majority (61%) of participants reported at least one ACE. A dose-response relationship between numbers of ACEs with risk for opioid misuse was present. Compared to participants with no ACEs, participants with ≥4 ACEs and 0–3 ACEs were 2.93 (95% CI: 1.95, 4.39; p<0.001) and 1.96 (95% CI: 1.46, 2.65; p<0.001) times more likely to be at risk for opioid misuse, respectively. Having at least one existing or past health condition significantly mediated the association. Conclusions: Our findings suggest need to include assessment of ACEs as a screening criterion for opioid prescription and administration among college-aged individuals. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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