69 results on '"John A. Occhino"'
Search Results
2. Robotic-Assisted Surgery for Pelvic Organ Prolapse: Sacrocolpopexy and Beyond
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Brian J. Linder and John A. Occhino
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Obstetrics and Gynecology ,Surgery - Published
- 2023
3. Cost-effectiveness Analysis of Early Sling Loosening Versus Delayed Sling Lysis in the Management of Voiding Dysfunction After Midurethral Sling Placement
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Darlene Vargas Maldonado, Kevin M. Wymer, John B. Gebhart, Annetta M. Madsen, John A. Occhino, Emanuel C. Trabuco, and Brian J. Linder
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Urology ,Obstetrics and Gynecology ,Surgery - Published
- 2022
4. Perioperative outcomes of reconstructive surgery for apical prolapse in the very elderly: a national contemporary analysis
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Sherif A. El-Nashar, Rubin Raju, John A. Occhino, Ghanshyam Yadav, and Graham C. Chapman
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Reconstructive surgery ,medicine.medical_specialty ,education.field_of_study ,030219 obstetrics & reproductive medicine ,Abdominal sacrocolpopexy ,business.industry ,Urology ,Population ,030232 urology & nephrology ,Obstetrics and Gynecology ,Perioperative ,medicine.disease ,Logistic regression ,Surgery ,03 medical and health sciences ,0302 clinical medicine ,Apical prolapse ,Coagulopathy ,medicine ,Lifetime risk ,education ,business - Abstract
It is predicted that the number of women aged 80 years or older will more than triple by 2050. In the US, women have a 13% lifetime risk of undergoing pelvic organ prolapse surgery. Our aim was to compare the perioperative outcomes following various reconstructive approaches for apical prolapse surgery in the very elderly. The National Surgical Quality Improvement Program database was used to identify women age ≥ 80 years of age who underwent reconstructive apical prolapse surgery from 2010 to 2017. Perioperative morbidity of vaginal colpopexy, minimally invasive sacrocolpopexy (MISC) and abdominal sacrocolpopexy (ASC) were compared. The primary outcome was the rate of composite serious complications. Univariate and multivariate logistic regression was used to identify independent predictors of serious complications. A total of 1012 patients were identified: vaginal (n = 792), MISC (n = 151) and ASC (n = 69). The composite serious complication rate was higher in the ASC group compared to vaginal/MISC groups (18.8% vs. 9.3% and 9.3%, p 85 years (aOR 1.98), operative time > 3 h (aOR 2.02), baseline dyspnea (aOR 2.17), “other race” (aOR 2.04), preoperative coagulopathy (aOR 2.92) and ASA (aOR 1.47) were associated with composite serious complications. ASC is associated with higher perioperative morbidity in the very elderly population. MISC and vaginal colpopexy have similar rates of composite serious complications; however, vaginal colpopexy is overall the safest approach in this population.
- Published
- 2021
5. Vesicouterine Fistula: A Robotic Approach
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Cassandra K. Kisby, Mary V Baker, and John A. Occhino
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Surgical repair ,medicine.medical_specialty ,Hysterectomy ,business.industry ,Urology ,Fistula ,medicine.medical_treatment ,Obstetrics and Gynecology ,medicine.disease ,Asymptomatic ,Vesicouterine fistula ,Surgery ,medicine ,Robotic surgery ,medicine.symptom ,Cesarean delivery ,business ,CT cystogram - Abstract
This video demonstrates surgical repair of a vesicouterine fistula via a robotic, uterine-sparing approach. In this video, we present a vesicouterine fistula, which occurred after cesarean delivery. The patient presented with cyclical hematuria 4 years following delivery. She underwent uterine-conserving robotic repair via excision of the fistula tract through an intentional cystotomy. The uterus and bladder were closed in multiple layers. The patient tolerated the procedure well, and CT cystogram 6 weeks following surgery demonstrated no concern for defect or recurrent fistulization. The patient was asymptomatic 9 months following her procedure. Repair of a vesicouterine fistula may be safely completed via a minimally invasive approach without need for routine hysterectomy.
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- 2021
6. Exosome-Induced Vaginal Tissue Regeneration in a Porcine Mesh Exposure Model
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Emanuel C. Trabuco, Tyler J. Rolland, Paul G. Stalboerger, Ilya Y. Shadrin, Boran Zhou, Atta Behfar, Cassandra K. Kisby, and John A. Occhino
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medicine.medical_specialty ,Swine ,Urology ,Pilot Projects ,Exosomes ,Polypropylenes ,Exosome ,Suture (anatomy) ,Fibrosis ,medicine ,Animals ,Humans ,business.industry ,Regeneration (biology) ,Obstetrics and Gynecology ,Surgical Mesh ,medicine.disease ,Vaginal mesh ,Epithelium ,Vaginal tissue ,Apheresis ,medicine.anatomical_structure ,Vagina ,Female ,Surgery ,business - Abstract
OBJECTIVES The purpose of this study was to explore the utility of an injectable purified exosome product derived from human apheresis blood to (1) augment surgical closure of vaginal mesh exposures, and (2) serve as a stand-alone therapy for vaginal mesh exposure. METHODS Sixteen polypropylene meshes (1×1-3×3 cm) were implanted in the vaginas of 7 Yorkshire-crossed pigs by urogynecologic surgeons (day 0). On day 7, group 1 underwent surgical intervention via vaginal tissue suture reclosure with (n=2 pigs, n=4 meshes) or without (n=2 pigs, n=4 meshes) exosome injection; group 2 underwent medical intervention with an exosome injection (n=3, n=8 meshes). One animal in group 2 was given oral 2'-deoxy-5-ethynyluridine to track cellular regeneration. Euthansia occurred at 5 weeks. RESULTS Mesh exposures treated with surgical closure alone experienced reexposure of the mesh. Exosome treatment with or without surgical closure resulted in partial to full mesh exposure resolution up to 3×3 cm. Exosome-treated tissues had significantly thicker regenerated epithelial tissue (208 μm exosomes-only and 217 μm surgery+exosomes, versus 80 μm for surgery-only; P < 0.05); evaluation of 2'-deoxy-5-ethynyluridine confirmed de novo regeneration throughout the epithelium and underlying tissues. Capillary density was significantly higher in the surgery+exosomes group (P = 0.03). Surgery-only tissues had a higher inflammatory and fibrosis response as compared with exosome-treated tissues. CONCLUSIONS In this pilot study, exosome treatment augmented healing in the setting of vaginal mesh exposure, reducing the incidence of mesh reexposure after suture closure and decreasing the area of mesh exposure through de novo tissue regeneration after exosome injection only. Further study of varied local tissue conditions and mesh configurations is warranted.
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- 2021
7. Perioperative Outcomes of Rectovaginal Fistula Repair Based on Surgical Approach: A National Contemporary Analysis
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Elizabeth B. Habermann, Katherine A. Bews, Brian J. Linder, John A. Occhino, Erryn E Tappy, and Rubin Raju
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Adult ,Reoperation ,medicine.medical_specialty ,Adolescent ,Databases, Factual ,Urology ,030232 urology & nephrology ,MEDLINE ,Hematocrit ,Perineum ,Logistic regression ,Patient Readmission ,Young Adult ,03 medical and health sciences ,Gynecologic Surgical Procedures ,Postoperative Complications ,0302 clinical medicine ,Diabetes mellitus ,Abdomen ,medicine ,Humans ,Aged ,Retrospective Studies ,Aged, 80 and over ,030219 obstetrics & reproductive medicine ,medicine.diagnostic_test ,business.industry ,Rectovaginal Fistula ,Obstetrics and Gynecology ,Perioperative ,Middle Aged ,medicine.disease ,Surgery ,Logistic Models ,Treatment Outcome ,Rectovaginal fistula ,Concomitant ,Multivariate Analysis ,Vagina ,Cohort ,Female ,business - Abstract
OBJECTIVE To compare the perioperative outcomes of transvaginal/perineal and abdominal approaches to rectovaginal fistula (RVF) repair using a national multicenter cohort. METHODS The American College of Surgeons National Surgical Quality Improvement Program database was utilized to identify women undergoing RVF repair from 2005 to 2016. Emergent cases and those with concomitant bowel diversion were excluded. Baseline patient demographics, procedure characteristics, 30-day postoperative complications, return to the operating room, and readmission were evaluated. Baseline characteristics were compared across surgical approach. Multivariable logistic regression models identified preoperative characteristics independently associated with postoperative complications. RESULTS A total of 2288 women underwent RVF repair: 1560 (68.2%) via transvaginal/perineal approach and 728 (31.8%) via abdominal approach. Patients undergoing transvaginal/perineal repair were significantly younger (median age, 46 years vs 63 years), with lower American Society for Anesthesiologist (ASA) scores, and less frequency of diabetes mellitus, dyspnea, severe chronic obstructive pulmonary disease, hypertension, disseminated cancer, and bleeding disorders (all P < 0.01). Those undergoing abdominal repair had higher rates of major complications (25.8% vs 8.7%), minor complications (13.5% vs 6.3%), and readmission (13.2% vs 7.8%). On multivariable analyses, ASA Class 3/4, disseminated cancer, and hematocrit
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- 2020
8. LeFort partial colpocleisis: tips and technique
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Rubin Raju, John A. Occhino, and Brian J. Linder
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Stress incontinence ,medicine.medical_specialty ,030219 obstetrics & reproductive medicine ,Sling (implant) ,Lidocaine ,business.industry ,Urology ,medicine.medical_treatment ,030232 urology & nephrology ,Obstetrics and Gynecology ,Urinary incontinence ,medicine.disease ,Curettage ,Surgery ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Aortic valve replacement ,Colpocleisis ,medicine ,medicine.symptom ,business ,Cervix ,medicine.drug - Abstract
We present a video describing the technical considerations for performing a LeFort colpocleisis. A 79-year-old woman presented with a symptomatic vaginal bulge. She was not sexually active, and had no desire to maintain the vaginal canal. Her history was significant for aortic valve replacement, chronic anticoagulation, and a cardiac pacemaker. She had uterine procidentia, with occult stress urinary incontinence. After discussing options, she elected to undergo LeFort colpocleisis. Following sharp endometrial curettage, hydro-dissection was performed with lidocaine and epinephrine. Rectangular patches of vaginal epithelium were excised anteriorly and posteriorly, and the proximal margins were re-approximated, inverting the cervix. Following this, the lateral margins were re-approximated to create lateral channels. The anterior and posterior rectangles were then plicated, reducing the prolapse. The vaginal incision was closed transversely. A retropubic, synthetic, mid-urethral sling was placed, and an aggressive posterior colpoperineorrhaphy was performed. Her postoperative course was uncomplicated. At her 6-week follow-up she had no recurrent prolapse, denied stress incontinence, and was voiding without difficulty. Important tips for LeFort colpocleisis include ruling out underlying malignancy, using lidocaine with epinephrine for hydrodissection, creating adequate lateral channels, closure in multiple layers with excellent hemostasis, and an aggressive posterior repair.
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- 2019
9. Urinary Tract Infection After Hysterectomy for Benign Gynecologic Conditions or Pelvic Reconstructive Surgery
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Jennifer J. Schmitt, Daniel A. Carranza Leon, Chetna Arora, John B. Gebhart, Sherif A. El-Nashar, Ruchira Singh, and John A. Occhino
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Adult ,Reconstructive surgery ,medicine.medical_specialty ,medicine.medical_treatment ,Urinary system ,Hysterectomy ,Logistic regression ,Pelvic Organ Prolapse ,Pelvis ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Humans ,Medicine ,030212 general & internal medicine ,Aged ,Retrospective Studies ,030219 obstetrics & reproductive medicine ,business.industry ,Obstetrics and Gynecology ,Retrospective cohort study ,General Medicine ,Odds ratio ,Middle Aged ,Plastic Surgery Procedures ,Urinary Retention ,Surgery ,Postmenopause ,Urinary Tract Infections ,Female ,Hormone therapy ,business ,Genital Diseases, Female ,Cohort study - Abstract
Objective To report rates and identify risk factors for urinary tract infection (UTI) after hysterectomy for benign conditions or combined with pelvic reconstructive surgery. Methods This is a cohort study that included women who underwent hysterectomy either for benign gynecologic conditions or hysterectomy combined with pelvic reconstructive surgery from January 1, 2012, through June 30, 2014, at a single institution. The primary outcome was UTI within 8 weeks of surgery. Logistic regression modeling was used to develop a model for predicting UTI after surgery. Results Of 1,156 women included in the study, 136 (11.8%, 95% CI 10.0-13.8) developed UTI within 8 weeks. Women who underwent hysterectomy for a benign gynecologic condition that was not combined with pelvic reconstructive surgery had an overall UTI rate of 7.3% (95% CI 5.6-9.3) vs 21.7% (95% CI 17.6-26.4) after hysterectomy combined with pelvic reconstructive surgery. After adjusting for hormone therapy use, the following were independent variables associated with postoperative UTI: premenopausal status with an adjusted odds ratio (OR) of 1.80 (95% CI 1.11-2.99), anterior vaginal wall prolapse with an adjusted OR of 4.39 (95% CI 2.77-6.97), and postvoid residual greater than 150 mL with an adjusted OR of 2.38 (95% CI 1.12-4.36). Using this model, postoperative UTI rates ranged from 4.3% to 59.4% with high postvoid residual and presence of anterior prolapse having the strongest association. Conclusion There are wide variations in the rate of UTI after hysterectomy for begin disease including pelvic reconstructive surgery. These variations can be explained with a model based on available preoperative data.
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- 2018
10. Impact of Repeat Dosing and Mesh Exposure Chronicity on Exosome-Induced Vaginal Tissue Regeneration in a Porcine Mesh Exposure Model
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John A. Occhino, Cassandra K. Kisby, Lillian T Peng, Emanuel C. Trabuco, Paul G. Stalboerger, Ilya Y. Shadrin, and Atta Behfar
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Swine ,Urology ,Multiple dose ,Exosomes ,Exosome ,Pelvic Organ Prolapse ,Andrology ,Medicine ,Animals ,Humans ,Dosing ,Suburethral Slings ,Wound Healing ,business.industry ,Regeneration (biology) ,Obstetrics and Gynecology ,Surgical Mesh ,Epithelium ,Vaginal tissue ,medicine.anatomical_structure ,Vagina ,Surgery ,Female ,Analysis of variance ,Wound healing ,business - Abstract
OBJECTIVE The aim of the study was to compare vaginal wound healing after exosome injection in a porcine mesh exposure model with (1) single versus multiple dose regimens and (2) acute versus subacute exposure. METHODS Six 80-kg Yorkshire-crossed swine each had 2 polypropylene meshes implanted to create the vaginal mesh exposure model. Animals were divided into 3 groups based on number and timing of exosome injection: (1) single purified exosome product (PEP) injection (acute-single), (2) weekly PEP injections (acute-weekly, 4 total injections), and (3) delayed single injection (subacute-single). Acute and subacute injections occurred 1 and 8 weeks after mesh implantation, respectively. EdU, a thymidine analog, was given twice weekly after the first injection to track tissue regeneration. Euthanasia and tissue analysis occurred 4 weeks after the first injection. ImageJ was used to quantify epithelial thickness, cellular proliferation, and capillary density. Statistical analysis was performed using analysis of variance and post hoc Tukey test. RESULTS Acute-single PEP injection tissues mirrored pilot study results, validating replication of protocol. Within the acute groups, weekly dosing resulted in 1.5× higher epithelial thickness (nonsignificant), 1.8× higher epithelial proliferation (P < 0.05), and 1.5× higher regenerated capillary density (P < 0.05) compared with single injection. Regarding chronicity of the exposure, the subacute group showed 1.7× higher epithelial proliferation (nonsignificant) and similar capillary density and epithelial thickness as compared with the acute group. CONCLUSIONS Exosome redosing resulted in significantly greater epithelial proliferation with significantly higher regenerated capillary density, leading to a trend toward thicker epithelium. Subacute exposure exhibited similar regeneration to acute exposure despite a delayed injection timeline. These results contribute to a growing body of preclinical research demonstrating utility of exosomes in pelvic floor disorders.
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- 2021
11. Ergonomic Robotic Console Configuration in Gynecologic Surgery: An Interventional Study
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M. Susan Hallbeck, Michaela E. McGree, Amy L. Weaver, Melissa M. Morrow, Bethany R. Lowndes, John A. Occhino, Erik D. Hokenstad, and Gretchen E. Glaser
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Male ,medicine.medical_specialty ,medicine.medical_treatment ,Psychological intervention ,Tertiary care ,03 medical and health sciences ,0302 clinical medicine ,Gynecologic Surgical Procedures ,Robotic Surgical Procedures ,medicine ,Humans ,Robotic surgery ,Prospective Studies ,Prospective cohort study ,Pain score ,030219 obstetrics & reproductive medicine ,Hysterectomy ,business.industry ,Obstetrics and Gynecology ,Human factors and ergonomics ,Surgery ,Occupational Diseases ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Upper limb ,Female ,Ergonomics ,business - Abstract
Study Objective The objectives of this study were to (1) pilot a robotic console configuration methodology to optimize ergonomic posture, and (2) determine the effect of this intervention on surgeon posture and musculoskeletal discomfort. Design This was an institutional review board–approved prospective cohort study conducted from February 2017 to October 2017. Setting A single tertiary care midwestern academic medical center. Participants Six fellowship-trained gynecologic surgeons, proficient in robotic hysterectomy, were recruited: 3 men and 3 women. Interventions Each surgeon performed 3 robotic hysterectomies using their self-selected robotic console settings (preintervention). Then, a robotic console ergonomic intervention protocol was implemented by trained ergonomists to improve posture and decrease time in poor ergonomic positions. Each surgeon then performed 3 robotic hysterectomies using the ergonomic intervention settings (postintervention). All surgeries used the da Vinci Xi surgical system (Intuitive Surgical, Inc., Sunnyvale, CA) and were the first case of the day. The surgeons wore inertial measurement unit (IMU) sensors on their head, chest, and bilateral upper arms during surgery. The IMU sensors are equipped with accelerometers, gyroscopes, and magnetometers to give objective measurements of body posture. IMU data were then analyzed to determine the percentage of time spent in ergonomically risky postures as categorized using a modified rapid upper limb assessment. Before and after each hysterectomy, the surgeons completed identical questionnaires for an assessment of musculoskeletal pain/discomfort. The outcome measurements were compared pre- versus postintervention on the basis of fitting generalized linear mixed models that handled the individual surgeon as a random effect and “setting” as a fixed effect. Measurements and Main Results With regard to the IMU posture results, there was a significant decrease in time spent in the moderate- to high-risk neck position and a decrease in average neck angle after the ergonomic intervention. The average percentage of time spent in moderate- to high-risk categories was significantly lower for the neck (mean, 54.3% vs 21.0%; p = .008) and right upper arm (mean, 15.5% vs 0.9%; p = .02) when using the intervention settings compared with the surgeons’ settings. Pain score results: There were fewer reported increases in neck (4 [22%] vs 1 [6%]) and right shoulder (4 [22%] vs 2 [11%]) pain or discomfort after completion of robotic hysterectomy postintervention versus preintervention; however, these differences did not attain statistical significance (p = .12 and p = .37, respectively). Conclusion An ergonomic robotic console intervention demonstrated effectiveness and improved objective surgeon posture at the console when compared with the surgeons’ self-selected settings.
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- 2020
12. A National Contemporary Analysis of Perioperative Outcomes of Open versus Minimally Invasive Sacrocolpopexy
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Elizabeth B. Habermann, Amy E. Glasgow, Boris Gershman, Katherine A. Bews, John A. Occhino, and Brian J. Linder
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medicine.medical_specialty ,Blood transfusion ,Databases, Factual ,Urology ,medicine.medical_treatment ,030232 urology & nephrology ,Severity of Illness Index ,Pelvic Organ Prolapse ,Perioperative Care ,Cohort Studies ,03 medical and health sciences ,Gynecologic Surgical Procedures ,0302 clinical medicine ,Humans ,Medicine ,Aged ,Proportional Hazards Models ,Retrospective Studies ,Laparotomy ,Hospital readmission ,030219 obstetrics & reproductive medicine ,Abdominal sacrocolpopexy ,Surgical approach ,business.industry ,Robotic Surgical Procedures ,Perioperative ,Middle Aged ,medicine.disease ,Surgery ,Pulmonary embolism ,Logistic Models ,Colposcopy ,Current Procedural Terminology ,Female ,Laparoscopy ,business - Abstract
We evaluated the perioperative morbidity of open abdominal sacrocolpopexy and minimally invasive sacrocolpopexy using data on a contemporary nationwide cohort.We used the ACS (American College of Surgeons) NSQIP® (National Surgical Quality Improvement Program) database to identify women who underwent abdominal or minimally invasive sacrocolpopexy from 2010 to 2016. Associations of surgical approach with 30-day complications, blood transfusion, prolonged hospitalization and reoperation were evaluated by logistic regression. Hospital readmission within 30 days was calculated by the person-years method and Cox proportional hazard models.A total of 4,362 women underwent sacrocolpopexy, including abdominal sacrocolpopexy in 1,179 (27%) and minimally invasive sacrocolpopexy in 3,183 (73%). The proportion of minimally invasive sacrocolpopexy increased during the study period from 70% in 2010 to 82% in 2016. Baseline characteristics were similar between the treatment groups aside from a higher rate of chronic obstructive pulmonary disease (p = 0.03) and higher preoperative albumin (p 0.0001) among abdominal sacrocolpopexy cases. Compared to abdominal sacrocolpopexy, minimally invasive sacrocolpopexy was associated with lower rates of 30-day complications (p = 0.001), deep vein thrombosis/pulmonary embolism (p = 0.02), surgical site infections (p0.0001), shorter hospitalization (p 0.0001) and fewer blood transfusions (p = 0.01). Minimally invasive sacrocolpopexy was also associated with a lower 30 person-days readmission rate (2% vs 2.7%, p ≤0.0001) and 30-day reoperation rate (1.1% vs 1.4%, p0.0001). On multivariable analysis minimally invasive sacrocolpopexy was independently associated with a reduced risk of 30-day complications (OR 0.46, 95% CI 0.28, 0.76, p = 0.002), blood transfusion (OR 0.33, 95% CI 0.15, 0.74, p = 0.007), prolonged hospitalization (OR 0.16, 95% CI 0.12, 0.23, p0.001) and readmission (HR 0.62, 95% CI 0.41, 0.96, p = 0.03).Minimally invasive sacrocolpopexy was associated with reduced rates of 30-day complications, blood transfusion, prolonged hospitalization and hospital readmission compared to abdominal sacrocolpopexy.
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- 2018
13. Readmission and reoperation after midurethral sling
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Amy E. Glasgow, Erik D. Hokenstad, John A. Occhino, and Elizabeth B. Habermann
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Reoperation ,medicine.medical_specialty ,Urinary Incontinence, Stress ,Urology ,Urinary system ,Urinary incontinence ,Patient Readmission ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Risk Factors ,Statistical significance ,medicine ,Humans ,030212 general & internal medicine ,Retrospective Studies ,Suburethral Slings ,030219 obstetrics & reproductive medicine ,medicine.diagnostic_test ,Urinary retention ,business.industry ,Obstetrics and Gynecology ,General Medicine ,Cystoscopy ,Length of Stay ,Middle Aged ,Quality Improvement ,Surgery ,Cohort ,Current Procedural Terminology ,Female ,medicine.symptom ,business ,Body mass index - Abstract
We aimed to determine the rate of readmission and reoperation for patients undergoing midurethral sling (MUS) placement for stress urinary incontinence (SUI). The American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database was queried to identify all isolated MUS placed from 2012 through 2015 using the Current Procedural Terminology 4 (CPT-4) code for MUS with or without cystoscopy (57,288 ± 52,000). The cohort was then reviewed for unplanned, related readmissions and reoperations within 30 days of MUS placement. Isolated MUS was placed in 9910 patients. Fifty-eight (0.59%) patients were readmitted and 81 (0.82%) had reoperation. The most common indications for readmission were related to the urinary tract, i.e., urinary retention (27.6%), non-surgical-site-related infection (15.5%), and medical related issues (15.5%) The most common indications for reoperation were urinary tract (60.5%), gastrointestinal (7.4%), and gynecologic, i.e., examination under anesthesia (6.2%). Body mass index (BMI) was less (p = 0.001), and operative time (p = 0.014) and length of stay (LOS) (p = 0.001) longer in patients who were readmitted. Those who underwent reoperation had longer LOS than those who did not have reoperation (p
- Published
- 2018
14. Management of presacral bleeding
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Erik D. Hokenstad and John A. Occhino
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medicine.medical_specialty ,030219 obstetrics & reproductive medicine ,Hemostatic Techniques ,business.industry ,Urology ,Bone wax ,030232 urology & nephrology ,Obstetrics and Gynecology ,Hemorrhage ,Omental flap ,Pelvis ,Surgery ,03 medical and health sciences ,Gynecologic Surgical Procedures ,0302 clinical medicine ,Suture (anatomy) ,Cadaver ,Hemostasis ,Gelatin matrix ,medicine ,Fresh frozen ,Humans ,Female ,business ,Pelvic surgery - Abstract
The objective of this video is to demonstrate a variety of available techniques that can be used in the management of acute presacral bleeding. In this video, we demonstrate different methods for the management of presacral bleeding utilizing a fresh frozen cadaver. Presacral bleeding is a potentially catastrophic complication that can be encountered during pelvic surgery, particularly sacrocolpopexy. Various techniques exist to achieve hemostasis in the event of uncontrolled bleeding. This video demonstrates some of the available methods that may be employed in the management of presacral bleeding. The methods demonstrated in this video include direct pressure, pelvic packing, gelatin matrix, bone wax, thumb tack, surgical clip, suture, oxidized regenerated cellulose, omental flap, electrocautery, muscle fragment welding, gelatin matrix combined with thrombin, and microporous polysaccharide spheres. Familiarity with these techniques and product availability will aid in the management of acute presacral bleeding.
- Published
- 2019
15. 12: Six-month urinary incontinence outcomes in women undergoing endometrial cancer surgery with concomitant surgery for stress urinary incontinence, non-surgical incontinence treatment, and endometrial cancer surgery alone: the cancer of the uterus and treatment of incontinence (CUTI) study
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Kyle Wohlrab, Katina Robison, Chanelle J. Howe, Carolyn K. McCourt, Matthew Carlson, Elizabeth Lokich, John A. Occhino, Holly E. Richter, Kerri S. Bevis, Paul DiSilvestro, Melissa A. Clark, David D. Rahn, C. Chen, A.K. Brown, Jerry L. Lowder, Christine Luis, Vivian W. Sung, Gretchen E. Glaser, C. Raker, Elena Tunitsky, Stephanie L. Wethington, Gena C. Dunivan, and Evelyn Hall
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medicine.medical_specialty ,business.industry ,Endometrial cancer ,Uterus ,Obstetrics and Gynecology ,Cancer ,Urinary incontinence ,medicine.disease ,Surgery ,medicine.anatomical_structure ,Concomitant ,medicine ,medicine.symptom ,business - Published
- 2019
16. Robot-assisted vesicovaginal fistula repair via a transvesical approach
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Erik D. Hokenstad, John A. Occhino, and Brian J. Linder
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medicine.medical_specialty ,Uterine fibroids ,Urology ,Fistula ,030232 urology & nephrology ,Urinary incontinence ,Hysterectomy ,Omental flap ,Vesicovaginal fistula ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Robotic Surgical Procedures ,medicine ,Humans ,Abdominal hysterectomy ,Transvesical approach ,030219 obstetrics & reproductive medicine ,Vesicovaginal Fistula ,business.industry ,Obstetrics and Gynecology ,Cystotomy ,Middle Aged ,medicine.disease ,Surgery ,Treatment Outcome ,Urologic Surgical Procedures ,Female ,Absorbable sutures ,medicine.symptom ,business - Abstract
The objective of this video is to demonstrate a technique for robot-assisted vesicovaginal fistula (VVF) repair utilizing a mini cystotomy with a transvesical approach. A 53-year-old female developed a VVF after she underwent an abdominal hysterectomy for uterine fibroids at an outside facility. She was referred to us following two failed VVF repairs (one vaginal, one abdominal with bladder bivalving and omental flap). After discussing options, she underwent a robotic VVF repair via a transvesical approach. Following port placement, the space of Retzius was mobilized. An intentional cystotomy was made and the camera and working arms advanced into the bladder. The fistula was identified and circumferentially mobilized. The fistula was closed in three layers using absorbable sutures, and care was taken to avoid the ureters. The patient’s postoperative recovery was uncomplicated. Follow-up imaging was performed via cystogram at 4 weeks and showed resolution of the fistula. A robot-assisted transvesical approach using a mini cystotomy to VVF repair is a useful technique especially when previous surgical planes have been used in prior repairs and failed. It maintains a minimally invasive approach and may avoid complications associated with an open abdominal approach.
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- 2018
17. Long-term outcomes and predictors of failure after surgery for stage IV apical pelvic organ prolapse
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Christopher J. Klingele, Amy L. Weaver, Deborah J. Rhodes, Brian J. Linder, Emanuel C. Trabuco, Michaela E. McGree, Sherif A. El-Nashar, Alain A. Mukwege, John B. Gebhart, and John A. Occhino
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Adult ,medicine.medical_specialty ,Urology ,medicine.medical_treatment ,Uterosacral ligament ,Kaplan-Meier Estimate ,Hysterectomy ,Severity of Illness Index ,Pelvic Organ Prolapse ,Young Adult ,03 medical and health sciences ,Gynecologic Surgical Procedures ,Postoperative Complications ,0302 clinical medicine ,Interquartile range ,Statistical significance ,Humans ,Medicine ,Treatment Failure ,030212 general & internal medicine ,Proportional Hazards Models ,030219 obstetrics & reproductive medicine ,business.industry ,Proportional hazards model ,Medical record ,Hazard ratio ,Age Factors ,Obstetrics and Gynecology ,Confidence interval ,Surgery ,Treatment Outcome ,medicine.anatomical_structure ,Vagina ,Female ,business - Abstract
The aim of this study was to compare outcomes after uterosacral ligament suspension (USLS) or sacrocolpopexy for symptomatic stage IV apical pelvic organ prolapse (POP) and evaluate predictors of prolapse recurrence. The medical records of patients managed surgically for stage IV apical POP from January 2002 to June 2012 were reviewed. A follow-up survey was sent to these patients. The primary outcome, prolapse recurrence, was defined as recurrence of prolapse symptoms measured by validated questionnaire or surgical retreatment. Survival time free of prolapse recurrence was estimated using the Kaplan–Meier method, and Cox proportional hazards models evaluated factors for an association with recurrence. Of 2633 women treated for POP, 399 (15.2%) had stage IV apical prolapse and were managed with either USLS (n = 355) or sacrocolpopexy (n = 44). Those managed with USLS were significantly older (p
- Published
- 2017
18. Determining Optimal Route of Hysterectomy for Benign Indications
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Amy L. Weaver, Sean C. Dowdy, John A. Occhino, John B. Gebhart, Daniel A. Carranza Leon, Jamie N. Bakkum-Gamez, Kalyan S. Pasupathy, and Jennifer J. Schmitt
- Subjects
Adult ,medicine.medical_specialty ,medicine.medical_treatment ,Clinical Decision-Making ,Operative Time ,Decision tree ,Hysterectomy ,Patient Readmission ,Article ,03 medical and health sciences ,0302 clinical medicine ,Robotic Surgical Procedures ,Hysterectomy, Vaginal ,medicine ,Humans ,Surgical Wound Infection ,Robotic surgery ,030212 general & internal medicine ,Hospital Costs ,Clinical decision ,Retrospective Studies ,030219 obstetrics & reproductive medicine ,business.industry ,General surgery ,Decision Trees ,Uterus ,Obstetrics and Gynecology ,Retrospective cohort study ,Organ Size ,Middle Aged ,Surgery ,body regions ,Tree (data structure) ,Urinary Tract Infections ,Cohort ,Female ,business ,Genital Diseases, Female ,Algorithms - Abstract
To evaluate practice change after initiation of a robotic surgery program using a clinical algorithm to determine the optimal surgical approach to benign hysterectomy.A retrospective postrobot cohort of benign hysterectomies (2009-2013) was identified and the expected surgical route was determined from an algorithm using vaginal access and uterine size as decision tree branches. We excluded the laparoscopic hysterectomy route. A prerobot cohort (2004-2005) was used to evaluate a practice change after the addition of robotic technology (2007). Costs were estimated.Cohorts were similar in regard to uterine size, vaginal parity, and prior laparotomy history. In the prerobot cohort (n=473), 320 hysterectomies (67.7%) were performed vaginally and 153 (32.3%) through laparotomy with 15.1% (46/305) performed abdominally when the algorithm specified vaginal hysterectomy. In the postrobot cohort (n=1,198), 672 hysterectomies (56.1%) were vaginal; 390 (32.6%) robot-assisted; and 136 (11.4%) abdominal. Of 743 procedures, 38 (5.1%) involved laparotomy and 154 (20.7%) involved robotic technique when a vaginal approach was expected. Robotic hysterectomies had longer operations (141 compared with 59 minutes, P.001) and higher rates of surgical site infection (4.7% compared with 0.2%, P.001) and urinary tract infection (8.1% compared with 4.1%, P=.05) but no difference in major complications (P=.27) or readmissions (P=.27) compared with vaginal hysterectomy. Algorithm conformance would have saved an estimated $800,000 in hospital costs over 5 years.When a decision tree algorithm indicated vaginal hysterectomy as the route of choice, vaginal hysterectomy was associated with shorter operative times, lower infection rate, and lower cost. Vaginal hysterectomy should be the route of choice when feasible.
- Published
- 2017
19. Prospective Implementation and Evaluation of a Decision-Tree Algorithm for Route of Hysterectomy
- Author
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John B. Gebhart, Jamie N. Bakkum-Gamez, Amy L. Weaver, John A. Occhino, Michaela E. McGree, Sean C. Dowdy, Mary V. Baker, Jennifer J. Schmitt, and Kalyan S. Pasupathy
- Subjects
Adult ,medicine.medical_specialty ,medicine.medical_treatment ,Hysterectomy ,Decision Support Techniques ,Predictive Value of Tests ,Laparotomy ,medicine ,Humans ,Prospective Studies ,Prospective cohort study ,Abdominal hysterectomy ,Vaginal route ,business.industry ,Decision Trees ,Obstetrics and Gynecology ,General Medicine ,Surgery ,Gynecology ,Predictive value of tests ,Hysterectomy vaginal ,Examination Under Anesthesia ,Female ,business ,Algorithms - Abstract
Objective To evaluate the rate of vaginal hysterectomy and outcomes after initiation of a prospective decision-tree algorithm to determine the optimal surgical route of hysterectomy. Methods A prospective algorithm to determine optimal route of hysterectomy was developed, which uses the following factors: history of laparotomy, uterine size, and vaginal access. The algorithm was implemented at our institution from November 24, 2015, to December 31, 2017, for patients requiring hysterectomy for benign indications. Expected route of hysterectomy was assigned by the algorithm and was compared with the actual route performed to identify compliance compared with deviation. Surgical outcomes were analyzed. Results Of 365 patients who met inclusion criteria, 202 (55.3%) were expected to have a total vaginal hysterectomy, 57 (15.6%) were expected to have an examination under anesthesia followed by total vaginal hysterectomy, 52 (14.2%) were expected to have an examination under anesthesia followed by robotic-assisted total laparoscopic hysterectomy, and 54 (14.8%) were expected to have an abdominal or robotic-laparoscopic route of hysterectomy. Forty-six procedures (12.6%) deviated from the algorithm to a more invasive route (44 robotic, two abdominal). Seven patients had total vaginal hysterectomy when robotic-assisted total laparoscopic hysterectomy or abdominal hysterectomy was expected by the algorithm. Overall, 71% of patients were expected to have a vaginal route of hysterectomy per the algorithm, of whom 81.5% had a total vaginal hysterectomy performed; more than 99% of the total vaginal hysterectomies attempted were successfully completed. Conclusion Vaginal surgery is feasible, carries a low complication rate with excellent outcomes, and should have a place in gynecologic surgery. National use of this prospective algorithm may increase the rate of total vaginal hysterectomy and decrease health care costs.
- Published
- 2020
20. 2671 Lefort Colpocleisis
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Rubin Raju, John A. Occhino, and Brian J. Linder
- Subjects
Pessary ,medicine.medical_specialty ,Past medical history ,Tubal ligation ,medicine.diagnostic_test ,business.industry ,medicine.medical_treatment ,Obstetrics and Gynecology ,Urinary incontinence ,Cystoscopy ,medicine.disease ,Surgery ,Dilation and curettage ,Aortic valve replacement ,Colpocleisis ,medicine ,medicine.symptom ,business - Abstract
Video Objective To present the technical considerations and pearls to performing a LeFort Colpocleisis. Setting Patient is a 76 year old female with history of a vaginal bulge for the past 6 months and a failed pessary trial. She also reports urge-predominant mixed urinary incontinence with worsening stress urinary incontinence with reduction of the pelvic organ prolapse. She is not sexually active and does not plan on any future sexual activity. She does not have any abnormal pap smears and denies postmenopausal bleeding. Her past medical history is significant for multiple comorbid conditions including cardiac issues with a pacemaker, chronic kidney disease, hypertension and diabetes. Her past surgical history is complicated by aortic valve replacement (porcine valve), tubal ligation and a left total knee replacement. On exam she has a Stage IV uterine, anterior and posterior compartment prolapse with positive occult stress urinary incontinence. Urodynamic studies reveal stress urinary incontinence, no detrusor overactivity and an elevated post void residual (125 ml after 241 ml void). She was counseled regarding management options including conservative options (observation or repeat pessary trial), restorative procedures (vaginal vault suspension or sacrocolpopexy), or an obliterative procedure such as a LeFort Colpocleisis. Interventions The patient opted for a LeFort Colpocleisis. She underwent a Dilation and curettage, a LeFort colpocleisis, Posterior colpoperineorrhaphy, Cystoscopy and a Midurethral Sling Placement. Conclusion The technical considerations for performing a LeFort Colpocleisis include ruling out malignancy prior to surgery, adequate lateral channels for uterine drainage, the use of lidocaine with epinephrine, closure in multiple layers with excellent hemostasis and an aggressive posterior colpoperineorrhaphy.
- Published
- 2019
21. Reoperation for Urinary Incontinence After Retropubic and Transobturator Sling Procedures
- Author
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Sherif A. El Nashar, Amy L. Weaver, Daniel S. Elliott, John A. Occhino, Emanuel C. Trabuco, D. Carranza, Brian J. Linder, Michaela E. McGree, John B. Gebhart, and Christopher J. Klingele
- Subjects
Adult ,Reoperation ,medicine.medical_specialty ,Urinary Incontinence, Stress ,Urinary Bladder ,Urinary incontinence ,Sling (weapon) ,Body Mass Index ,Cohort Studies ,Recurrence ,medicine ,Humans ,Cumulative incidence ,Intraoperative Complications ,Aged ,Retrospective Studies ,Suburethral Slings ,Urinary retention ,business.industry ,Hazard ratio ,Obstetrics and Gynecology ,Retrospective cohort study ,Middle Aged ,Urinary Retention ,Surgery ,Treatment Outcome ,Cohort ,Urologic Surgical Procedures ,Female ,medicine.symptom ,business ,Cohort study - Abstract
Objective To compare the reoperation rates for recurrent stress urinary incontinence (SUI) after retropubic and transobturator sling procedures. Methods We conducted a retrospective cohort study of all women who underwent midurethral sling procedures at a single institution for primary SUI between 2002 and 2012. To minimize bias, women in the two groups were matched on age, body mass index, isolated compared with combined procedure, and preoperative diagnosis. The primary outcome was defined as reoperation for recurrent SUI. Secondary outcomes included intraoperative complications and mesh-related complications requiring reoperation after the index sling procedure. Results We identified 1,881 women who underwent a sling procedure for primary SUI-1,551 retropubic and 330 transobturator. There was no difference between groups in any of the evaluated baseline variables in the covariate-matched cohort of 570 with retropubic slings and 317 with transobturator slings; results herein are based on the covariate-matched cohort. Women undergoing a transobturator sling procedure had an increased risk of reoperation for recurrent SUI compared with women undergoing a retropubic sling procedure (hazard ratio 2.42, 95% CI 1.37-4.29). The cumulative incidence of reoperation for recurrent SUI by 8 years was 5.2% (95% CI 3.0-7.4%) in the retropubic group and 11.2% (95% CI 6.4-15.8%) in the transobturator group. Women in the retropubic group had a significantly higher rate of intraoperative complications compared with women in the transobturator group (13.7% [78/570] vs 4.7% [15/317]; difference=9.0%, 95% CI for difference 5.3-12.6%); the majority of this difference was due to bladder perforation (7.0% [40/570] vs 0.6% [2/317]; difference=6.4%, 95% CI for difference 4.1-8.7%). The cumulative incidence of sling revision for urinary retention plateaued at 3.2% and 0.4% by 5 years in the two groups. Conclusion Women with primary SUI treated with a retropubic sling procedure have significantly lower cumulative incidence of reoperation for recurrent SUI compared with women who were treated with a transobturator sling procedure. Retropubic slings were associated with a higher risk of sling revision for urinary retention.
- Published
- 2019
22. Characteristics of opioid users undergoing surgery for pelvic organ prolapse
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Leah S. Scarlotta, John A. Occhino, Amy E. Glasgow, Elizabeth B. Habermann, and D.A. Leach
- Subjects
medicine.medical_specialty ,Urology ,030232 urology & nephrology ,Prescription data ,Pelvic Organ Prolapse ,03 medical and health sciences ,0302 clinical medicine ,Medicine ,Humans ,Practice Patterns, Physicians' ,Pelvic organ ,Pain, Postoperative ,030219 obstetrics & reproductive medicine ,Surgical approach ,Morphine ,business.industry ,Medical record ,Obstetrics and Gynecology ,Surgery ,Analgesics, Opioid ,Opioid ,Concomitant ,Cohort ,business ,Body mass index ,medicine.drug - Abstract
Understanding demographic and opioid utilization patterns of preoperative opioid users compared with opioid-naive patients undergoing surgical treatment for pelvic organ prolapse (POP) better informs opioid prescribing. A cohort of preoperative opioid users undergoing surgery for POP from 1 January 2012 through 30 May 2017 was identified. Electronic medical records were utilized to obtain pain scores and prescription data. The cohort was organized by surgical approach, number of concomitant procedures, and patient age. These factors were then matched to pain scores, opioid quantity prescribed at discharge, and subsequent refills. Pain scores and opioid use were evaluated for correlation. Results were then compared with similar data previously published for opioid-naive patients undergoing surgical treatment of POP. Preoperative opioid users were younger (55.5 [14.7] vs 59.5 [12.7]; p = 0.002), of higher body mass index (BMI; 29.2 [5.4] vs 28.6 [10.3]; p = 0.04), and less likely Caucasian (90.3% vs 95.9%; p = 0.002) than opioid-naive patients. After matching for these differences, opioid users reported higher pain scores (3.5 [2.2] vs 2.6 [1.8]; p =
- Published
- 2019
23. Perioperative Complications in Minimally Invasive Sacrocolpopexy Versus Transvaginal Mesh in the Management of Pelvic Organ Prolapse: Analysis of a National Multi-institutional Dataset
- Author
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Katherine A. Bews, Cassandra K. Kisby, Brian J. Linder, John A. Occhino, and Elizabeth B. Habermann
- Subjects
Reoperation ,medicine.medical_specialty ,Urology ,030232 urology & nephrology ,Datasets as Topic ,Patient Readmission ,Pelvic Organ Prolapse ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Gynecologic Surgical Procedures ,Postoperative Complications ,Medicine ,Humans ,Blood Transfusion ,Retrospective Studies ,Pelvic organ ,030219 obstetrics & reproductive medicine ,business.industry ,Obstetrics and Gynecology ,Perioperative ,Length of Stay ,Middle Aged ,Surgical Mesh ,Vaginal repair ,Vaginal mesh ,Surgery ,Urinary Tract Infections ,Female ,Laparoscopy ,business - Abstract
The objective of this study was to evaluate perioperative complications in women who underwent minimally invasive sacrocolpopexy (MISC) versus mesh-augmented vaginal repair (vaginal mesh) for pelvic organ prolapse.We identified patients undergoing MISC and vaginal mesh via Current Procedural Terminology codes from the American College of Surgeons National Surgical Quality Improvement Program database from 2005 to 2016. Those undergoing concomitant hysterectomy were excluded. Univariate analyses were performed to compare baseline characteristics and 30-day complications. Multivariable logistic regression models were constructed to assess the association between surgical approach and complications, prolonged hospitalization, reoperation, and blood transfusion. A multivariable Cox proportional hazard model was used to evaluate hospital readmission.A total of 5722 patients were identified (2573 MISC [45%], 3149 vaginal mesh [55%]). Those undergoing MISC repairs had a significantly lower rate of urinary tract infection (3.1 vs 4.2%; P = 0.03) and blood transfusion (0.5 vs 1.4%; P0.001). There was no difference in reoperation rate (1.3 vs 1.6%; P = 0.35). Multivariable analysis showed no significant association of MISC with overall (odds ratio [OR], 0.91; P = 0.44), major (OR, 1.30; P = 0.31), or minor complication (OR, 0.85; P = 0.26). There were lower odds of receiving a blood transfusion (OR, 0.44; P = 0.02) and higher odds of prolonged hospitalization (2 days; OR, 1.47; P = 0.003) for the MISC group. There was no difference in reoperation (OR, 0.79; P = 0.38) or hospital readmissions (hazard ratio, 1.25, P = 0.32).Minimally invasive sacrocolpopexy was associated with a lower rate of blood transfusion than transvaginal mesh placement. There was no significant difference in 30-day complication rates, reoperation, or readmission between these prolapse procedures when performed without concomitant hysterectomy.
- Published
- 2019
24. A National Contemporary Analysis of Perioperative Outcomes for Vaginal Vault Prolapse: Minimally Invasive Sacrocolpopexy Versus Nonmesh Vaginal Surgery
- Author
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Amy E. Glasgow, Boris Gershman, John A. Occhino, Brian J. Linder, and Katherine A. Bews
- Subjects
Adult ,medicine.medical_specialty ,Sacrum ,Adolescent ,Urology ,medicine.medical_treatment ,030232 urology & nephrology ,Pelvic Organ Prolapse ,Cohort Studies ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Gynecologic Surgical Procedures ,Postoperative Complications ,medicine ,Humans ,Minimally Invasive Surgical Procedures ,Aged ,Retrospective Studies ,Aged, 80 and over ,030219 obstetrics & reproductive medicine ,Hysterectomy ,Proportional hazards model ,business.industry ,Obstetrics and Gynecology ,Retrospective cohort study ,Odds ratio ,Perioperative ,Middle Aged ,United States ,Surgery ,Treatment Outcome ,Cohort ,Vagina ,Female ,business ,Vaginal Vault Prolapse ,Cohort study - Abstract
OBJECTIVE The aim of this study was to compare the perioperative morbidity of minimally invasive sacrocolpopexy (MISC) and nonmesh apical vaginal surgeries for repair of vaginal vault prolapse using data from a contemporary nationwide cohort. METHODS The American College of Surgeons' National Surgical Quality Improvement Program database was used to identify women who underwent apical prolapse surgery via vaginal approach or MISC from 2010 to 2016. Those undergoing concomitant hysterectomy or transvaginal mesh placement were excluded. Associations of surgical approach with 30-day complications, prolonged hospitalization, and reoperation were evaluated using logistic regression. Readmission within 30 days was calculated using the person-years method and Cox proportional hazards models. RESULTS Overall, 6390 women underwent surgery, including 3852 (60%) via vaginal approach and 2538 (40%) via MISC. Patients undergoing MISC were younger (P < 0.0001) and less likely to have hypertension (P = 0.04) or chronic obstructive pulmonary disease (P = 0.008), with lower American Society of Anesthesiologists scores (P < 0.0001) and higher preoperative hematocrit (P = 0.009). The MISC cohort had a lower unadjusted rates of minor complications (3.9% vs 5.6%; P = 0.004), urinary tract infection (3.3% vs 4.8%; P = 0.004), and prolonged hospitalization (5.2% vs 7.9%; P < 0.0001), with a higher rate of nephrologic (P = 0.01) complications. On multivariable analysis, there were no significant associations of MISC with the risk of 30-day complications (odds ratio [OR], 1.51; 95% confidence interval [CI], 0.92-2.51; P = 0.11), prolonged hospitalization (OR, 0.96; 95% CI, 0.76-1.21; P = 0.72), readmission (HR 1.03; 95% CI, 0.71-1.49;P = 0.88), or reoperation (OR, 0.95; 95% CI, 0.57-1.60; P = 0.86). CONCLUSIONS Minimally invasive sacrocolpopexy is associated with similar rates of 30-day complications, prolonged hospitalization, readmission, and reoperation compared with nonmesh vaginal surgeries for apical prolapse.
- Published
- 2019
25. Burch Retropubic Urethropexy Compared With Midurethral Sling With Concurrent Sacrocolpopexy
- Author
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Emanuel C. Trabuco, Michaela E. McGree, Amy L. Weaver, Maureen A. Lemens, John A. Occhino, John B. Gebhart, Roberta E. Blandon, and Christopher J. Klingele
- Subjects
medicine.medical_specialty ,Sling (implant) ,Urinary Incontinence, Stress ,medicine.medical_treatment ,Urinary incontinence ,Article ,Pelvic Organ Prolapse ,law.invention ,Urethropexy ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Randomized controlled trial ,law ,medicine ,Humans ,030212 general & internal medicine ,Suburethral Slings ,030219 obstetrics & reproductive medicine ,business.industry ,Obstetrics and Gynecology ,Odds ratio ,Middle Aged ,Confidence interval ,Surgery ,Treatment Outcome ,Concomitant ,Urologic Surgical Procedures ,Female ,medicine.symptom ,Complication ,business - Abstract
OBJECTIVE To compare efficacy and safety of retropubic Burch urethropexy and a midurethral sling in women with stress urinary incontinence (SUI) undergoing concomitant pelvic floor repair with sacrocolpopexy. METHODS Women were randomly assigned to Burch retropubic urethropexy (n=56) or retropubic midurethral sling (n=57) through dynamic allocation balancing age, body mass index, history of prior incontinence surgery, intrinsic sphincter deficiency, preoperative incontinence diagnosis, and prolapse stage. Overall and stress-specific continence primary outcomes were ascertained with validated questionnaires and a blinded cough stress test. RESULTS Enrollment was June 1, 2009, through August 31, 2013. At 6 months, no difference was found in overall (29 midurethral sling [51%] compared with 23 Burch [41%]; P=.30) (odds ratio [OR] 1.49, 95% confidence interval [CI] 0.71-3.13) or stress-specific continence rates (42 midurethral sling [74%] compared with 32 Burch [57%]; P=.06) (OR 2.10, 95% CI 0.95-4.64) between groups. However, the midurethral sling group reported greater satisfaction (78% compared with 57%; P=.04) and were more likely to report successful surgery for SUI (71% compared with 50%; P=.04) and to resolve pre-existing urgency incontinence (72% compared with 41%; P=.03). No difference was found in patient global impression of severity or symptom improvement, complication rates, or mesh exposures. CONCLUSION There was no difference in overall or stress-specific continence rates between midurethral sling and Burch urethropexy groups at 6 months. However, the midurethral sling group reported better patient-centered secondary outcomes.
- Published
- 2016
26. Female Urethral Diverticulum
- Author
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John B. Gebhart, Sherif A. El-Nashar, Shunaha Kim-Fine, Ruchira Singh, Melissa M. Bacon, John A. Occhino, and Christopher J. Klingele
- Subjects
Adult ,Reoperation ,medicine.medical_specialty ,Urology ,Urinary system ,030232 urology & nephrology ,Urinary incontinence ,Article ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Recurrence ,Risk Factors ,Dysuria ,Urethral Diseases ,medicine ,Urethral diverticulum ,Humans ,Young adult ,Survival analysis ,Aged ,Hematuria ,Aged, 80 and over ,Suburethral Slings ,030219 obstetrics & reproductive medicine ,medicine.diagnostic_test ,business.industry ,Obstetrics and Gynecology ,Magnetic resonance imaging ,Middle Aged ,Magnetic Resonance Imaging ,Confidence interval ,Surgery ,Diverticulum ,Dyspareunia ,Treatment Outcome ,Urinary Incontinence ,Urinary Tract Infections ,Female ,medicine.symptom ,Tomography, X-Ray Computed ,business - Abstract
INTRODUCTION AND HYPOTHESIS To report on clinical presentation, diagnosis, and outcomes after treatment of female urethral diverticulum (UD). METHODS Using a record linkage system, women with a new diagnosis of UD at Mayo Clinic from January 1, 1980, through December 31, 2011, were identified. The presenting symptoms, clinical characteristics, diagnosis, and management of women presenting with UD were recorded. Outcomes after surgery were assessed using survival analysis. All statistical analyses were 2-sided and P values less than 0.05 were considered significant. Statistical analysis was done using SAS version 9.2 and JMP version 9.0 (SAS Institute Inc.). RESULTS A total of 164 cases were identified. Median age at diagnosis was 46 years (range, 21-83). The most common presenting symptom was recurrent urinary tract infection (98, 59.8%), followed by urinary incontinence (81, 49.4%), dysuria (62, 37.8%), dyspareunia (37, 22.6%), and hematuria (15, 9.1%). Examination revealed vaginal mass in 55 (33.5%) of the women. A significant trend was noted toward an increase in use of both magnetic resonance imaging and computed tomography (P < 0.001) along with a progressive decrease in use of urethrogram (P < 0.001) for diagnosis of UD over the years. Among 114 women who underwent surgical treatment for UD, 14(12.3%) women presented with recurrent UD and the 5-year recurrence rate after surgery for UD was 23.4% (95% confidence interval, 13.9-37.0) and a reoperation rate of 17.0% (95% confidence interval, 8.8-30.2) at 5 years. CONCLUSIONS Female UD is a rare and unique condition. Clinical presentation is usually nonspecific, and magnetic resonance imaging is commonly used for confirming the diagnosis. Recurrence is not uncommon, and repeat surgical intervention might be needed.
- Published
- 2016
27. Comparison of Short Term Outcomes of Sacral Nerve Stimulation and Intradetrusor Injection of OnabotulinumtoxinA (Botox) in Women With Refractory Overactive Bladder
- Author
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Emanuel C. Trabuco, Ruchira Singh, John A. Occhino, Christopher J. Klingele, Sherif A. El Nashar, and John B. Gebhart
- Subjects
medicine.medical_specialty ,Urology ,Urinary system ,Acetylcholine Release Inhibitors ,Electric Stimulation Therapy ,Urinary incontinence ,Humans ,Medicine ,Treatment Failure ,Botulinum Toxins, Type A ,Aged ,Retrospective Studies ,Urinary bladder ,Sacrococcygeal Region ,Urinary Bladder, Overactive ,business.industry ,Obstetrics and Gynecology ,Muscle, Smooth ,Retrospective cohort study ,Odds ratio ,Middle Aged ,medicine.disease ,Confidence interval ,Surgery ,medicine.anatomical_structure ,Overactive bladder ,Female ,medicine.symptom ,business ,Complication - Abstract
Objectives The aim of the study was to compare the short-term outcomes of sacral nerve stimulation (SNS) and intradetrusor injection of OnabotulinumtoxinA (Botox) for overactive bladder (OAB) symptoms refractory to behavioral modifications and pharmacologic therapy. Methods This is a retrospective cohort study evaluating the outcomes of SNS and Botox procedures that were performed for refractory OAB symptoms at a tertiary care referral center. The primary outcome was "failure" of treatment that was defined as less than 50% improvement from the baseline symptoms at 6 months. Results Sixty-five SNS and 63 Botox procedures met the inclusion criteria. Women undergoing Botox were more likely to report failure 6 months after the intervention as compared with those undergoing SNS (20 [31.8%] vs 7 [10.8%], P = 0.003; unadjusted odds ratio = 3.85, confidence interval = 1.5-9.93; adjusted odds ratio = 4.47, confidence interval = 1.69-14.4). However, there was no difference in the proportion of women who were started on antimuscarinic medications for persistent urgency urinary incontinence after both procedures (12 [18.5%] women in SNS group and 17 [27%] women in the Botox group, P = 0.249). The most common complication of the SNS procedure was wound related (8 [12.3%]), whereas the most common complication of the Botox procedure was urinary tract infection (31 [49.2%]). Conclusions The SNS resulted in lower failure rates at 6 months when performed for refractory OAB symptoms as compared with the Botox procedure. However, further studies are needed to evaluate the long-term cost-effectiveness of both procedures.
- Published
- 2015
28. Does adjuvant treatment increase risk of midurethral sling complications after concomitant surgery for endometrial cancer and stress urinary incontinence?
- Author
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Gena C. Dunivan, Christine Luis, Paul DiSilvestro, Gretchen E. Glaser, Carolyn K. McCourt, Lindsey Beffa, Kerri S. Bevis, C. Raker, E. Proussaloglou, Amita Kulkarni, Katina Robison, John A. Occhino, Elizabeth Lokich, A.K. Brown, G. Chen, K. Miller, Stephanie L. Wethington, E. Tunitsky, Matthew Carlson, and Kyle Wohlrab
- Subjects
medicine.medical_specialty ,Sling (implant) ,business.industry ,Endometrial cancer ,medicine.medical_treatment ,Obstetrics and Gynecology ,Urinary incontinence ,medicine.disease ,Surgery ,Oncology ,Concomitant ,Medicine ,medicine.symptom ,business ,Adjuvant - Published
- 2020
29. 72: Characteristics of opioid users undergoing surgery for pelvic organ prolapse
- Author
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D.A. Leach, Amy E. Glasgow, John A. Occhino, and Elizabeth B. Habermann
- Subjects
medicine.medical_specialty ,Pelvic organ ,Opioid ,business.industry ,medicine ,Obstetrics and Gynecology ,business ,Surgery ,medicine.drug - Published
- 2019
30. Outcomes of Vaginal Hysterectomy With and Without Perceived Contraindications to Vaginal Surgery
- Author
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Jennifer J. Schmitt, John A. Occhino, Amy L. Weaver, John B. Gebhart, and Michaela E. McGree
- Subjects
Adult ,medicine.medical_specialty ,Intraoperative Complication ,Urology ,medicine.medical_treatment ,Contraindications, Procedure ,03 medical and health sciences ,0302 clinical medicine ,Postoperative Complications ,Hysterectomy, Vaginal ,Medicine ,Humans ,030212 general & internal medicine ,Obesity ,Intraoperative Complications ,Contraindication ,Retrospective Studies ,030219 obstetrics & reproductive medicine ,Hysterectomy ,business.industry ,Obstetrics ,Cesarean Section ,Uterus ,Obstetrics and Gynecology ,Postoperative complication ,Retrospective cohort study ,Odds ratio ,Length of Stay ,Middle Aged ,Debulking ,Confidence interval ,Treatment Outcome ,Surgery ,Female ,business - Abstract
Objective The aim of this study was to compare outcomes of vaginal hysterectomy between patients with and without the following perceived contraindications to vaginal surgery: uterine weight greater than 280 g, prior cesarean delivery, no vaginal parity, and obesity. Methods Retrospective cohort of benign vaginal hysterectomies between 2009 and 2013 was obtained. Outcomes included uterine debulking, transfusion, intraoperative complications, length of stay, and Accordion grade 2+ postoperative complications. For each outcome, the association between the presence of each contraindication and the outcome was evaluated using univariate and multivariate logistic regression models. Results Among 692 vaginal hysterectomies, 11% (76/691) had a uterine weight greater than 280 g, 11.3% (78/690) had no vaginal parity, 14.9% (103/690) had a history of cesarean delivery, and 37.7% (248/657) had a body mass index of 30 kg/m or greater; 110 (15.9%) had 2 or more contraindications. Uterine debulking occurred in 146 women (21.1%), and both uterine weight greater 280 g (adjusted odds ratio, 39.2; 95% confidence interval, 18.4-83.5) and prior cesarean delivery (adjusted odds ratio, 2.1; 95% confidence interval, 1.2-3.7) were significantly associated with an increased likelihood of uterine debulking after adjusting for age, hematologic disease, and preoperative diagnosis. None of the contraindications were significantly associated with need for a blood transfusion, presence of an intraoperative complication, length of stay greater than 2 days, or presence of an Accordion grade 2+ postoperative complication, which occurred in 2.7%, 2.5%, 14.0%, and 6.9% of all women, respectively. Conclusions Vaginal hysterectomy can be safely performed with favorable outcomes, even in women with a uterus greater than 280 g, prior cesarean delivery, no vaginal parity, and obesity. Our findings challenge several perceived contraindications to vaginal hysterectomy.
- Published
- 2017
31. The Mayo Technique for Vaginal Hysterectomy
- Author
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John A. Occhino
- Subjects
medicine.medical_specialty ,medicine.anatomical_structure ,Hysterectomy ,Culdoplasty ,business.industry ,medicine.medical_treatment ,Hysterectomy vaginal ,Vagina ,medicine ,business ,Vaginal Vault Prolapse ,Surgery - Abstract
The Mayo technique for vaginal hysterectomy incorporates basic principles of surgery that promote safety and efficiency and help to decrease postoperative complications. The technique has been refined and modified over time to minimize the risk of post-hysterectomy vaginal vault prolapse (enterocele).
- Published
- 2017
32. Extravesical robotic ureteral reimplantation for ureterovaginal fistula
- Author
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Igor Frank, John A. Occhino, and Brian J. Linder
- Subjects
medicine.medical_specialty ,Urinary Fistula ,Urology ,Fistula ,medicine.medical_treatment ,030232 urology & nephrology ,Urinary incontinence ,Anastomosis ,03 medical and health sciences ,Gynecologic Surgical Procedures ,0302 clinical medicine ,Ureter ,Robotic Surgical Procedures ,medicine ,Humans ,Ureteral Diseases ,Hydronephrosis ,Hysterectomy ,business.industry ,Vaginal Fistula ,Obstetrics and Gynecology ,Stent ,Middle Aged ,medicine.disease ,Surgery ,surgical procedures, operative ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Female ,medicine.symptom ,business ,Ureteral reimplantation - Abstract
We present a video describing the technical considerations for performing an extravesical robotic ureteral reimplantation. A 55-year old woman presented with urinary incontinence secondary to a ureterovaginal fistula after robotic-assisted hysterectomy. After failure of more conservative measures, she proceeded to a robotic ureteral reimplantation. Following port placement, the ureter is identified at the level of the iliac vessels and dissected circumferentially. The ureter is dissected free to the level of the ureterovaginal fistula, transected, and the distal remnant ligated. The ureter is spatulated, a cystotomy created, and a running anastomosis with mucosa-to-mucosa apposition performed over a stent. Care is taken to ensure it is tension free. The integrity of the anastomosis is tested with retrograde filling of the bladder. Postoperatively, a drainage catheter is left to allow for adequate healing. Follow-up imaging is performed to ensure a patent anastomosis. The patient had an uncomplicated postoperative course. A cystogram showed adequate healing at 10 days, and the stent was removed at 6 weeks. A follow-up renal ultrasound 6 weeks later showed no hydronephrosis. Extravesical robotic ureteral reimplantation is a useful technique for managing ureterovaginal fistula; here we highlight pertinent technical considerations.
- Published
- 2017
33. Outcomes of Rectovaginal Fistula Repair
- Author
-
Heidi K. Chua, Amy L. Weaver, Jenifer N. Byrnes, Kristin C. Mara, Benjamin M. Faustich, Jennifer J. Schmitt, and John A. Occhino
- Subjects
Adult ,medicine.medical_specialty ,Urology ,Fistula ,medicine.medical_treatment ,Kaplan-Meier Estimate ,Infections ,03 medical and health sciences ,Ileostomy ,0302 clinical medicine ,Gynecologic Surgical Procedures ,Recurrence ,medicine ,Humans ,Aged ,Pelvic Neoplasms ,Retrospective Studies ,Surgical repair ,Aged, 80 and over ,Pelvic exenteration ,business.industry ,Proctocolectomy ,Rectovaginal Fistula ,Obstetrics and Gynecology ,Retrospective cohort study ,Middle Aged ,medicine.disease ,Inflammatory Bowel Diseases ,Surgery ,Treatment Outcome ,Rectovaginal fistula ,030220 oncology & carcinogenesis ,Etiology ,030211 gastroenterology & hepatology ,Female ,business - Abstract
OBJECTIVES Rectovaginal fistulae (RVF) often represent surgical challenges, and treatment must be individualized. We describe outcomes after primary surgical repair stratified by fistula etiology and surgical approach. METHODS This retrospective cohort study included women who underwent surgical management of RVF at a tertiary care center between July 1, 2001 and December 31, 2013. Cases were stratified according to the following etiology: cancer (RVF-C), inflammatory bowel disease or infectious (RVF-I), and other (RVF-O). Patients with prior surgical treatment of RVF were excluded. Surgical approaches included local (seton, plug), transvaginal or endorectal, abdominal, diversion alone, or definitive (completion proctocolectomy with permanent colostomy or pelvic exenteration). Recurrence-free survival was estimated using the Kaplan-Meier method, and comparisons between subgroups were evaluated based on fitting Cox proportional hazards models. Censoring occurred at last relevant clinical follow-up. Factors contributing to recurrence-free survival were evaluated including age, body mass index, smoking status, fistula etiology, ileostomy, and surgical approach. RESULTS During the study period, 107 women underwent surgical repair of RVF. The most common fistula etiology was RVF-I (54.2%), followed by RVF-O (23.4%), and RVF-C (22.4%). Ninety-four women underwent fistula repair by the local (29.9%), transvaginal/endorectal (25.2%), abdominal approach (19.6%), or diversion alone (13.1%), whereas 13 underwent definitive surgery (12.2%). Recurrence-free survival was significantly different depending on surgical approach (P < 0.001), but not etiology (P = 0.71). Recurrence-free survival (95% confidence interval) at 1 year after surgery was 35.2% (21.8%-56.9%) for the local approach, 55.6% (37.0%-83.3%) for the transvaginal or endorectal approach, 95% (85.9%-100%) for the abdominal approach, and 33.3% (15%-74.2%) for those with diversion only. CONCLUSIONS Recurrence rates after RVF repair are high and did not differ by fistula etiology. Abdominal repair of RVF had significantly fewer recurrences.
- Published
- 2017
34. Vaginal vs. robotic hysterectomy for patients with endometrial cancer: A comparison of outcomes and cost of care
- Author
-
Amy L. Weaver, William A. Cliby, Sean C. Dowdy, C.C. Nitschmann, Jamie N. Bakkum-Gamez, John A. Occhino, Carrie L. Langstraat, Andrea Mariani, and Francesco Multinu
- Subjects
medicine.medical_specialty ,medicine.medical_treatment ,Cost-Benefit Analysis ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Robotic Surgical Procedures ,medicine ,Hysterectomy, Vaginal ,Humans ,Progression-free survival ,Retrospective Studies ,030219 obstetrics & reproductive medicine ,business.industry ,Endometrial cancer ,Obstetrics and Gynecology ,Retrospective cohort study ,Health Care Costs ,medicine.disease ,Surgery ,Endometrial Neoplasms ,Robotic hysterectomy ,Treatment Outcome ,Oncology ,030220 oncology & carcinogenesis ,Propensity score matching ,Lymph Node Excision ,Lymphadenectomy ,Female ,Cost of care ,business ,Cohort study - Abstract
Objective To compare outcomes and cost for patients with endometrial cancer undergoing vaginal hysterectomy (VH) or robotic hysterectomy (RH), with or without lymphadenectomy (LND). Methods Patients undergoing planned VH (and laparoscopic LND) or RH (and robotic LND) between January 2007 and November 2012 were reviewed. Patients with stage IV disease, synchronous cancer, synchronous surgery, or treated with palliative intent were excluded. Patients were objectively triaged to LND per institutional protocol based on frozen section. Outcomes were compared between VH and RH groups matched 1:1 on propensity scores. Results VH was planned in 153 patients; 60 (39%) had concurrent LND while 93 (61%) were low risk and did not require LND. RH was planned in 398 patients; 225 (56%) required concurrent LND and 173 (44%) did not. Among 50 PS-matched pairs without LND, there was no significant difference in complications, length of stay, readmission, or progression free survival. However, median operative time was 1.3h longer and median 30-day cost $3150 higher for RH compared to VH (both p Among patients requiring LND, 42 PS-matched pairs were identified. Median operative time was not different when pelvic and para-aortic LND was performed, and 12min longer in the VH group for pelvic LND alone (p=0.03). Median 30-day cost was $921 higher for RH compared to VH when LND was required (p=0.08). Conclusion Utilization of vaginal hysterectomy for endometrial cancer results in similar surgical and oncologic outcomes and lower costs compared to RH and should be considered for appropriate patients with a low risk of requiring LND.
- Published
- 2017
35. Readmission and Reoperation After Surgery for Pelvic Organ Prolapse
- Author
-
Amy E. Glasgow, Elizabeth B. Habermann, Erik D. Hokenstad, and John A. Occhino
- Subjects
Reoperation ,medicine.medical_specialty ,Urology ,Operative Time ,Logistic regression ,Pelvic Organ Prolapse ,03 medical and health sciences ,0302 clinical medicine ,Gynecologic Surgical Procedures ,Recurrence ,medicine ,Unplanned readmission ,Operating time ,Humans ,Surgical Wound Infection ,030212 general & internal medicine ,Prospective Studies ,Pop surgery ,Retrospective Studies ,Pelvic organ ,030219 obstetrics & reproductive medicine ,medicine.diagnostic_test ,business.industry ,General surgery ,Obstetrics and Gynecology ,Cystoscopy ,General Medicine ,Length of Stay ,Middle Aged ,United States ,Surgery ,Cohort ,Female ,Stents ,business ,Surgical site infection - Abstract
OBJECTIVES We aimed to determine the rates of readmission and reoperation for patients undergoing surgery for pelvic organ prolapse (POP). METHODS The American College of Surgeons National Surgical Quality Improvement Program Participant User File was used to select all surgeries performed for POP from 2012 through 2014. The cohort was then reviewed for unplanned readmissions and unplanned reoperations within 30 days of POP surgery. Patient and procedural factors associated with readmission or reoperation were compared using χ analyses and Student t test. Multivariable logistic regression determined independent risk factors for both readmission and reoperation. RESULTS A total of 23,419 patients underwent surgery for POP. Of these, there were 435 (1.9%) readmissions and 341 (1.5%) reoperations within 30 days. Median numbers of days from index procedure to readmission or reoperation were 9 and 8 days, respectively. Those who were readmitted had higher American Society of Anesthesia (ASA) scores, longer operative times, and longer lengths of stay than those who were not readmitted (all P < 0.001). Patients who underwent unplanned reoperation also had higher ASA scores, longer operative times, and longer lengths of stay than those who did not undergo reoperation (all P < 0.01). The most common reasons for readmission were surgical site infection (SSI) (19.3%) and non-SSI (15.9%). The most common reason for reoperation was urologic (27.6%) such as cystoscopy or stent placement. CONCLUSIONS Readmission and reoperation rates are relatively low for patients undergoing surgery for POP. Infection, both SSI and non-SSI, accounted for 35.2% of readmissions. Identification of ASA score of 3 or higher, longer total operating time, and increased length of stay is associated with unplanned readmission and reoperation.
- Published
- 2017
36. Prospective Outcomes of a Pelvic Floor Rehabilitation Program Including Vaginal Electrogalvanic Stimulation for Urinary, Defecatory, and Pelvic Pain Symptomsa
- Author
-
Randina R. Harvey-Springer, Amy L. Weaver, John A. Occhino, Kristin C. Mara, Jennifer J. Schmitt, Ruchira Singh, and Felecia R. Fick
- Subjects
medicine.medical_specialty ,Visual analogue scale ,Urology ,medicine.medical_treatment ,Urinary system ,Electric Stimulation Therapy ,Biofeedback ,Pelvic Pain ,Pelvic Floor Disorders ,Article ,03 medical and health sciences ,0302 clinical medicine ,Pelvic floor dysfunction ,Behavior Therapy ,medicine ,Humans ,030212 general & internal medicine ,Prospective Studies ,Prospective cohort study ,030219 obstetrics & reproductive medicine ,Rehabilitation ,business.industry ,Pelvic pain ,Obstetrics and Gynecology ,Biofeedback, Psychology ,Middle Aged ,medicine.disease ,Combined Modality Therapy ,Exercise Therapy ,body regions ,medicine.anatomical_structure ,Dyspareunia ,Treatment Outcome ,Urinary Incontinence ,Patient Satisfaction ,Anesthesia ,Vagina ,Surgery ,Female ,medicine.symptom ,business ,Fecal Incontinence - Abstract
OBJECTIVES This study evaluated our experience after implementing a pelvic floor rehabilitation program including behavioral modification, biofeedback, and vaginal electrogalvanic stimulation (EGS). METHODS This prospective cohort study evaluated outcomes of patients with pelvic floor dysfunction (urinary or defecatory dysfunction, pelvic pain/dyspareunia) who underwent pelvic floor rehabilitation. Patients received 4 to 7 sessions (1 every 2 weeks) including biofeedback and concluded with 30 minutes of vaginal EGS. Surveys assessed subjective changes in symptoms; success was evaluated using a 10-point visual analog scale (VAS) at the final session (10 = most successful). Paired comparisons of responses at baseline and final treatment were evaluated. RESULTS Ninety-four patients were followed up through therapy completion. Treatment indications included urinary (89.4%), defecatory (33.0%), and pelvic pain or dyspareunia (30.9%); 44.7% of patients had a combination of indications. Among women with urinary symptoms, the percentage reporting leakage decreased from 92.9% to 79.3% (P = 0.001), leakage at least daily decreased from 69.0% to 39.5% (P < 0.001), daily urgency with leakage decreased from 42.7% to 19.5% (P = 0.001), daily urgency without leakage decreased from 41.5% to 18.3% (P < 0.001), and median VAS rating (0 = not at all, 10 = a great deal) of daily life interference decreased from 5 to 1.5 (P < 0.001). The median success ratings were 8, 8, and 7 for treatment of urinary symptoms, pelvic pain/dyspareunia, and bowel symptoms, respectively. CONCLUSIONS An aggressive pelvic rehabilitation program including biofeedback with vaginal EGS had a high rate of self-reported subjective success and satisfaction and should be considered a nonsurgical treatment option in patients with pelvic floor dysfunction.
- Published
- 2017
37. 14: Postoperative opioid prescribing following gynecologic surgery for pelvic organ prolapse
- Author
-
Amy E. Glasgow, John A. Occhino, Elizabeth B. Habermann, and D.A. Leach
- Subjects
medicine.medical_specialty ,Pelvic organ ,business.industry ,Obstetrics and Gynecology ,Medicine ,business ,Opioid prescribing ,Surgery - Published
- 2018
38. 49: Ergonomic strain during robotic hysterectomy
- Author
-
Erik D. Hokenstad, John A. Occhino, C.L. Langstraat, B.R. Lowndes, Christopher J. Klingele, S. Hallbeck, and G.E. Glaser
- Subjects
Robotic hysterectomy ,medicine.medical_specialty ,business.industry ,medicine ,Obstetrics and Gynecology ,Strain (injury) ,medicine.disease ,business ,Surgery - Published
- 2018
39. Concurrent surgical treatment of urinary incontinence at the time of endometrial cancer surgery is associated with improved quality of life 6 months after cancer surgery: Cancer of the uterus and treatment of incontinence (CUTI) study
- Author
-
Gretchen E. Glaser, M. Clark, Christine Luis, Chanelle J. Howe, G. Chen, Stephanie L. Wethington, Elizabeth Lokich, John A. Occhino, Jerry L. Lowder, Carolyn K. McCourt, E. Tunitsky, David D. Rahn, Vivian W. Sung, Gena C. Dunivan, A.K. Brown, Holly E. Richter, Kerri S. Bevis, Matthew Carlson, Paul DiSilvestro, Katina Robison, Kyle Wohlrab, and C. Raker
- Subjects
medicine.medical_specialty ,business.industry ,Endometrial cancer ,Uterus ,Obstetrics and Gynecology ,Cancer ,Urinary incontinence ,medicine.disease ,Surgery ,medicine.anatomical_structure ,Oncology ,Quality of life ,medicine ,medicine.symptom ,business ,Surgical treatment ,Cancer surgery - Published
- 2019
40. 89: The effect of concomitant hysterectomy on complications following pelvic organ prolapse surgery
- Author
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Erik D. Hokenstad, John A. Occhino, Elizabeth B. Habermann, and Katherine A. Bews
- Subjects
Pelvic organ ,medicine.medical_specialty ,Hysterectomy ,business.industry ,Concomitant ,Prolapse surgery ,medicine.medical_treatment ,medicine ,Obstetrics and Gynecology ,business ,Surgery - Published
- 2019
41. 14: Defining continence following surgical treatment of stress urinary incontinence (SUI)
- Author
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John B. Gebhart, Emanuel C. Trabuco, John A. Occhino, Amy L. Weaver, Christopher J. Klingele, and Brian J. Linder
- Subjects
medicine.medical_specialty ,business.industry ,medicine ,Obstetrics and Gynecology ,Urinary incontinence ,medicine.symptom ,Surgical treatment ,business ,Surgery - Published
- 2019
42. 49: Perioperative complications in minimally invasive sacrocolpopexy versus transvaginal mesh in the management of vault prolapse: an analysis of a national multi-institutional dataset
- Author
-
C.K. Kisby, Elizabeth B. Habermann, Brian J. Linder, John A. Occhino, and Katherine A. Bews
- Subjects
medicine.medical_specialty ,business.industry ,Obstetrics and Gynecology ,Medicine ,Perioperative ,business ,Vault (organelle) ,Surgery - Published
- 2019
43. Managing Complications of Implanted Mesh
- Author
-
John B. Gebhart and John A. Occhino
- Subjects
Food and drug administration ,Pelvic organ ,medicine.medical_specialty ,Surgical mesh ,business.industry ,Pelvic pain ,medicine ,Mesh erosion ,Surgery ,medicine.symptom ,business - Abstract
The use of surgical mesh in gynecology has come under intense scrutiny over the past year. The US Food and Drug Administration released a public health notification in 2008 outlining the reported complications associated with mesh placement, followed by a safety communication update in 2011. Although implantation of any type of mesh can lead to complications, most are associated with transvaginal placement of mesh for the treatment of pelvic organ prolapse. This article briefly discusses the history of surgical mesh and how we arrived at our current inflection point. Standardized terminologies for describing mesh-related complications are reviewed. Lastly, management of common mesh-related complications are discussed, including the management of mesh extrusion and pelvic pain/dyspareunia.
- Published
- 2013
44. Vaginal Prolapse Repair—Native Tissue Repair versus Mesh Augmentation: Newer Isn’t Always Better
- Author
-
Shunaha Kim-Fine, John A. Occhino, and John B. Gebhart
- Subjects
medicine.medical_specialty ,Pelvic organ ,business.industry ,Prolapse repair ,Geriatrics gerontology ,Female urology ,Biochemistry ,Surgery ,Native tissue ,medicine ,business ,Vaginal surgery ,Molecular Biology ,Pelvic surgery - Abstract
The purpose of this article is to update the female urology and urogynecologic community on the controversy regarding approaches to vaginal surgery for pelvic organ prolapse. We will review the salient issues in traditional, vaginal native-tissue (NT) repair for pelvic organ prolapse. We intend to provide arguments advocating vaginal NT repair over that of vaginal mesh-augmented (MA) repair, and to show that newer is not always better.
- Published
- 2013
45. Surgical and non-surgical education practices in female pelvic medicine and reconstructive surgery fellowships within the United States
- Author
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Ruchira Singh, John B. Gebhart, Eilean L. Myer, and John A. Occhino
- Subjects
Reconstructive surgery ,medicine.medical_specialty ,Sling (implant) ,Surgical approach ,genetic structures ,business.industry ,General surgery ,education ,Uterosacral ligament ,Surgical procedures ,Surgery ,medicine.anatomical_structure ,Native tissue ,medicine ,Surgical education ,business ,health care economics and organizations ,Posterior colporrhaphy - Abstract
Data are scarce regarding surgical and non-surgical education in accredited Female Pelvic Medicine and Reconstructive Surgery (FPMRS) fellowships in theUnited States. We compared surgical and non-surgical and education among training programs and expected surgical comfort level with pelvic reconstructive procedures from the perspective of the fellow and program director. An online survey was distributed to program directors and fellows from the 39 accredited FPMRS fellowships at the time (2010). Domains evaluated in the survey were academic education requirements; surgical approaches to prolapse and to incontinence; other surgical procedures; and research and publication expectations. In total, forty fellows from 21 programs and directors from 27 programs. The most common surgical procedures performed for apical, anterior, and posterior prolapse were uterosacral ligament suspension, native tissue anterior colporrhaphy, and posterior colporrhaphy, respectively. Differences in perceived surgical comfort level were seen for coccygeus suspension, graftreinforced posterior colporrhaphy, rectus fascial sling, urethral bulking agent, cystoscopic ureteral stent placement and bowel repair. A greater proportion of program directors reported that fellows would be comfortable performing these procedures upon graduation than the proportion reported by the fellows themselves. Differences exist in FPMRS training nationwide, however, responding fellows appeared to be trained in multiple approaches to prolapse repair. Differences were seen in surgical comfort level as perceived by fellows and program directors.
- Published
- 2013
46. Outcomes of Robotic Sacrocolpopexy Using Only Absorbable Suture for Mesh Fixation
- Author
-
Emanuel C. Trabuco, John B. Gebhart, Mallika Anand, Christopher J. Klingele, Brian J. Linder, and John A. Occhino
- Subjects
Pessary ,medicine.medical_specialty ,Urology ,Absorbable suture ,030232 urology & nephrology ,Kaplan-Meier Estimate ,Pelvic Organ Prolapse ,Mesh fixation ,03 medical and health sciences ,0302 clinical medicine ,Robotic Surgical Procedures ,Interquartile range ,Medicine ,Humans ,Treatment Failure ,Polyglactin 910 ,Aged ,Retrospective Studies ,Fibrous joint ,030219 obstetrics & reproductive medicine ,business.industry ,Suture Techniques ,Obstetrics and Gynecology ,General Medicine ,Middle Aged ,Surgical Mesh ,Surgery ,medicine.anatomical_structure ,Median body ,Female ,Absorbable sutures ,business ,Vaginal Vault Prolapse - Abstract
OBJECTIVE The optimal suture selection for mesh attachment during robotic sacrocolpopexy (RSC) is currently unknown. Here, we sought to evaluate the outcomes of RSC using absorbable sutures for vaginal and sacral mesh attachment. METHODS We retrospectively reviewed 132 RSC surgeries that were performed for vaginal vault prolapse in the Division of Gynecologic Surgery at our institution from February 2007 to December 2013. All cases were performed with absorbable suture (polyglactin) for vaginal and sacral mesh fixation. Sacrocolpopexy failure was defined as patients undergoing either repeat prolapse surgery or pessary use for recurrent prolapse. The durability of RSC was assessed via Kaplan-Meier method. RESULTS The median age at surgery was 61.1 years (interquartile range [IQR], 55.6-68.2) and the median length of postoperative follow-up was 33 months (IQR, 15.7-57). The median body mass index was 26.5 kg/m (IQR, 24.3-29.7). During follow-up, 10 patients underwent prolapse retreatment. There were 2 apical recurrences, 4 distal anterior recurrences, 2 posterior recurrences, and, in 2 cases, the location was unknown. One apical recurrence was confirmed to be secondary to detachment of the mesh from the sacral promontory. Among those with recurrence, the median time to recurrence was 15.5 months (IQR, 4.22-35.9). Overall, the 1-year and 3-year freedom from repeat surgery rates were 96% and 93%, respectively. CONCLUSIONS With a median follow-up of 33 months, the use of absorbable suture for both vaginal and sacral attachments during RSC is effective. Further studies evaluating suture selection and mesh attachment techniques for RSC are needed.
- Published
- 2016
47. Total colpocleisis: technical considerations
- Author
-
John A. Occhino, John B. Gebhart, and Brian J. Linder
- Subjects
medicine.medical_specialty ,Urology ,medicine.medical_treatment ,Treatment outcome ,Hysterectomy ,Total colpocleisis ,Pelvic Organ Prolapse ,Gynecologic surgical procedures ,03 medical and health sciences ,0302 clinical medicine ,Gynecologic Surgical Procedures ,Colpocleisis ,medicine ,Humans ,030212 general & internal medicine ,Aged ,Pelvic organ ,030219 obstetrics & reproductive medicine ,business.industry ,Obstetrics and Gynecology ,Surgery ,medicine.anatomical_structure ,Treatment Outcome ,Vagina ,Female ,business - Abstract
We present a video describing the technical considerations for performing a total colpocleisis in the management of symptomatic post-hysterectomy pelvic organ prolapse.A 76-year old female presented with pelvic pressure and the presence of a palpable vaginal bulge. She had significant bother and had previously failed use of a pessary. She wasnot sexually active, with no plans for future sexual activity. Her medical history was significant for coronary artery disease with prior myocardial infarction. She had high-grade vaginal vault prolapse, without occult incontinence. After discussing observation, pessaries, restorative and obliterative procedures, she elected to undergo colpocleisis. Following hydrodissection with lidocaine with epinephrine, a quadrant-based dissection was performed to remove the vaginal epithelium circumferentially. Following this, serial purse string sutures were used to reduce the prolapse, with meticulous hemostasis. The vaginal epithelium was then closed transversely. Next, a perineorrhaphy was performed. The midline was plicated and the perineal body reconstructed.The patient had an uncomplicated postoperative course. At six-week follow-up she had no evidence of recurrent prolapse and was voiding without difficulty.Colpocleisis can provide excellent anatomic and subjective outcomes. Our goal is to highlight pertinent technical considerations in order to optimize patient outcomes.
- Published
- 2016
48. Risk of venous thromboembolism in patients undergoing surgery for pelvic organ prolapse
- Author
-
Elizabeth B. Habermann, Amy E. Glasgow, Erik D. Hokenstad, and John A. Occhino
- Subjects
Risk ,medicine.medical_specialty ,Multivariate analysis ,Urology ,Urologic Surgical Procedure ,Pelvic Organ Prolapse ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Postoperative Complications ,Risk Factors ,Statistical significance ,Medicine ,Humans ,030212 general & internal medicine ,Obesity ,Laparoscopy ,Aged ,030219 obstetrics & reproductive medicine ,medicine.diagnostic_test ,business.industry ,Incidence (epidemiology) ,Incidence ,Obstetrics and Gynecology ,Venous Thromboembolism ,Length of Stay ,Middle Aged ,Surgery ,medicine.anatomical_structure ,Multivariate Analysis ,Vagina ,Urologic Surgical Procedures ,Female ,business ,Venous thromboembolism ,Cohort study - Abstract
We sought to determine the incidence of venous thromboembolism (VTE) in patients undergoing surgery for pelvic organ prolapse (POP) based on surgical approach. The American College of Surgeons National Quality Improvement Program (NSQIP) database was used to select all surgeries performed for POP from 2005 to 2013. CPT-4 codes were grouped based on surgical approach: vaginal (VAG), laparoscopic sacrocolpopexy (LSC), or open abdominal sacrocolpopexy (ASC). Patient demographics, preoperative American Society of Anesthesiologists (ASA) classification system scores, and 30-day postoperative complications were obtained. Of the 26,103 women who underwent surgery for POP, 21,311 (81.7 %) underwent VAG, 3,346 (12.8 %) LSC, and 1,426 (5.5 %) ASC. VTE occurred in 36 patients (0.17 %) in the VAG group, 8 (0.24 %) in the LSC group, and 9 (0.63 %) in the ASC group. The ASC group had a significantly higher incidence of VTE compared with the VAG group (p
- Published
- 2015
49. 1: Implementation and evaluation of benign hysterectomy decision tree algorithm
- Author
-
John A. Occhino, John B. Gebhart, Kalyan S. Pasupathy, Michaela E. McGree, Amy L. Weaver, Sean C. Dowdy, Jennifer J. Schmitt, and Jamie N. Bakkum-Gamez
- Subjects
medicine.medical_specialty ,030219 obstetrics & reproductive medicine ,Hysterectomy ,business.industry ,Decision tree learning ,General surgery ,medicine.medical_treatment ,Obstetrics and Gynecology ,Surgery ,03 medical and health sciences ,0302 clinical medicine ,medicine ,030212 general & internal medicine ,business - Published
- 2017
50. 68: Readmission and reoperation after midurethral sling
- Author
-
Amy E. Glasgow, John A. Occhino, Elizabeth B. Habermann, and Erik D. Hokenstad
- Subjects
medicine.medical_specialty ,Sling (implant) ,business.industry ,medicine ,Obstetrics and Gynecology ,business ,Surgery - Published
- 2017
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