1. Blood cell indices as predictors of complicated appendicitis: A diagnostic study
- Author
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Julio César Moreno-Alfonso, Ada Molina Caballero, María Concepción Yárnoz Irazábal, and Alberto Pérez Martínez
- Subjects
Appendicitis ,Biomarkers ,Platelet-to-lymphocyte ratio ,Derived neutrophil-to-lymphocyte ratio ,Cellular indices ,Abdominal pain ,Pediatrics ,RJ1-570 ,Surgery ,RD1-811 - Abstract
Background: Appendicitis in children is associated with diagnostic complexity leading to delayed diagnosis. Such delays risk progression to complicated appendicitis. This study investigates the potential of cellular indices, including neutrophil-to-lymphocyte ratio (NLR), derived neutrophil-to-lymphocyte ratio (dNLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR), to differentiate uncomplicated (UA) from complicated appendicitis (CA). Methods: Diagnostic study of pediatric patients with acute appendicitis admitted to our hospital from 2021 to 2022. NLR, dNLR, PLR and MLR were compared between groups. Results: A total of 182 patients were enrolled: 116 cases with CA (63 % male, age 9.6 ± 5.5 years) and 66 patients with UA (67 % male, age 10.6 ± 2.7 years). All blood cell indices were significantly higher in the CA group than in the UA group (p=
- Published
- 2023
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