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Simple Summary: Our study aims to demonstrate and quantify the usefulness of three different AI models for lymph node involvement prediction in prostate cancer patients comparing the performance with current routinely used clinical nomograms. Knowing the lymph node involvement with accuracy and confidence can influence the type of surgical and therapeutic choice. PURPOSE: We aim to compare the performance of three different radiomics models (logistic regression (LR), random forest (RF), and support vector machine (SVM)) and clinical nomograms (Briganti, MSKCC, Yale, and Roach) for predicting lymph node involvement (LNI) in prostate cancer (PCa) patients. MATERIALS AND METHODS: The retrospective study includes 95 patients who underwent mp-MRI and radical prostatectomy for PCa with pelvic lymphadenectomy. Imaging data (intensity in T2, DWI, ADC, and PIRADS), clinical data (age and pre-MRI PSA), histological data (Gleason score, TNM staging, histological type, capsule invasion, seminal vesicle invasion, and neurovascular bundle involvement), and clinical nomograms (Yale, Roach, MSKCC, and Briganti) were collected for each patient. Manual segmentation of the index lesions was performed for each patient using an open-source program (3D SLICER). Radiomic features were extracted for each segmentation using the Pyradiomics library for each sequence (T2, DWI, and ADC). The features were then selected and used to train and test three different radiomics models (LR, RF, and SVM) independently using ChatGPT software (v 4o). The coefficient value of each feature was calculated (significant value for coefficient ≥ ±0.5). The predictive performance of the radiomics models and clinical nomograms was assessed using accuracy and area under the curve (AUC) (significant value for p ≤ 0.05). Thus, the diagnostic accuracy between the radiomics and clinical models were compared. RESULTS: This study identified 343 features per patient (330 radiomics features and 13 clinical features). The most significant features were T2_nodulofirstordervariance and T2_nodulofirstorderkurtosis. The highest predictive performance was achieved by the RF model with DWI (accuracy 86%, AUC 0.89) and ADC (accuracy 89%, AUC 0.67). Clinical nomograms demonstrated satisfactory but lower predictive performance compared to the RF model in the DWI sequences. CONCLUSIONS: Among the prediction models developed using integrated data (radiomics and semantics), RF shows slightly higher diagnostic accuracy in terms of AUC compared to clinical nomograms in PCa lymph node involvement prediction. [ABSTRACT FROM AUTHOR]

In this article, we propose a monitoring procedure based on a multilayer neural network with multivalued neurons (MLMVN) capable of preventing catastrophic failures of dc–dc converters. The neural classifier allows both the detection of any malfunction and its localization. Thanks to the low computational complexity, the proposed method operates online, estimating the deviations of the passive components from their nominal values: this allows control strategies to be promptly adopted and operation of the dc–dc converter to be kept in high efficiency and reliability conditions. Since measuring the voltage and current on each component increases the complexity of the system, a testability analysis is proposed with the aim of identifying the minimum number of measurements needed to distinguish the classes of failure. To make the testability phase easier and more intuitive, a graphical representation is proposed. As a case study, prognostic analysis has been applied to prevent catastrophic failures in a synchronous Zeta converter. Several fault conditions have been analyzed through simulations and experimental tests. The obtained results confirm the ability of the proposed method to prevent failures and, also, show that the application of MLMVN results in a better performance than classic solutions available in the literature, such as support vector machine. [ABSTRACT FROM AUTHOR]

In this paper, a monitoring method for DC-DC converters in photovoltaic applications is presented. The primary goal is to prevent catastrophic failures by detecting malfunctioning conditions during the operation of the electrical system. The proposed prognostic procedure is based on machine learning techniques and focuses on the variations of passive components with respect to their nominal range. A theoretical study is proposed to choose the best measurements for the prognostic analysis and adapt the monitoring method to a photovoltaic system. In order to facilitate this study, a graphical assessment of testability is presented, and the effects of the variable solar irradiance on the selected measurements are also considered from a graphical point of view. The main technique presented in this paper to identify the malfunction conditions is based on a Multilayer neural network with Multi-Valued Neurons. The performances of this classifier applied on a Zeta converter are compared to those of a Support Vector Machine algorithm. The simulations carried out in the Simulink environment show a classification rate higher than 90%, and this means that the monitoring method allows the identification of problems in the initial phases, thus guaranteeing the possibility to change the work set-up and organize maintenance operations for DC-DC converters. [ABSTRACT FROM AUTHOR]