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Your search keyword '"Loubinoux, Julien"' showing total 3 results
Start Over Author "Loubinoux, Julien" Topic streptococcus pyogenes
3 results on '"Loubinoux, Julien"'

1. Characterization of Streptococcus pyogenes isolates responsible for adult meningitis in France from 2003 to 2013.

Author

Plainvert C, Doloy A, Joubrel C, Maataoui N, Dmytruk N, Touak G, Collobert G, Fouet A, Poyart C, and Loubinoux J

Subjects
Adult, Aged, Aged, 80 and over, Antigens, Bacterial genetics, Bacterial Outer Membrane Proteins genetics, Carrier Proteins genetics, Cluster Analysis, Female, France epidemiology, Humans, Male, Meningitis, Bacterial epidemiology, Meningitis, Bacterial pathology, Middle Aged, Multilocus Sequence Typing, Shock, Septic epidemiology, Streptococcal Infections epidemiology, Streptococcal Infections pathology, Survival Analysis, Young Adult, Meningitis, Bacterial complications, Meningitis, Bacterial microbiology, Shock, Septic mortality, Streptococcal Infections complications, Streptococcal Infections microbiology, Streptococcus pyogenes classification, Streptococcus pyogenes isolation & purification
Abstract

Sixty-three cases of Streptococcus pyogenes meningitis in adults were studied. Three predominant emm types were associated with meningitis: emm1 (44%), emm3 (11%), and emm6 (11%). Streptococcal toxic shock syndrome and mortality rates were 40% and 38%, respectively., (Copyright © 2016 Elsevier Inc. All rights reserved.)

Published
2016
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2. Clonal spread of emm type 28 isolates of Streptococcus pyogenes that are multiresistant to antibiotics.

Author

Mihaila-Amrouche L, Bouvet A, and Loubinoux J

Subjects
Bacitracin pharmacology, Electrophoresis, Gel, Pulsed-Field, Humans, Microbial Sensitivity Tests, Streptococcus pyogenes drug effects, Streptococcus pyogenes isolation & purification, Anti-Bacterial Agents pharmacology, Bacterial Proteins genetics, Drug Resistance, Multiple, Pharyngitis microbiology, Streptococcal Infections diagnosis, Streptococcus pyogenes genetics, Streptococcus pyogenes pathogenicity
Abstract

Fifty-three pharyngitis-related and invasive isolates of Streptococcus pyogenes that are resistant to bacitracin were collected. They were also resistant to streptomycin, kanamycin, macrolides, lincosamides, and streptogramin B. These multiresistant isolates were of emm type 28 and clonally related as shown by pulsed-field gel electrophoresis.

Published
2004
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3. Epidemiological markers of group A streptococcal infections in France.

Author

Loubinoux J, Florent M, Merad B, Collobert G, and Bouvet A

Subjects
Base Sequence, DNA Primers, France epidemiology, Humans, Polymerase Chain Reaction, Prospective Studies, Streptococcal Infections microbiology, Streptococcal Infections epidemiology, Streptococcus pyogenes isolation & purification
Abstract

Background & Objectives: A limited number of biotypes, T-types, and emm-types have been found to be associated with invasive isolates of group A streptococci, confirming the involvement of the M protein in virulence and its importance as an epidemiological marker. In this study, the epidemiological markers in the clinical isolates of group A streptococci were compared in invasive and non invasive isolates., Methods: From 1998 to 2001, 141 invasive and 353 non invasive isolates in France were studied and their biotype, T-type, and emm-type were determined., Results: The invasive isolates were mostly obtained from blood whereas the non invasive isolates were isolated from throat. Most of the isolates were of biotype 1. The invasive isolates were mostly of the T-type 1 associated with emm-type 1. The T-type 4 associated with emm-type 4 and the T-type 28 associated with emm-type 28 were also frequent. Invasive isolates responsible for puerperal sepsis and non invasive isolates were mostly of the T-type 28 associated with emm-type 28., Interpretation & Conclusion: This study confirms the high prevalence of isolates of biotype 1, T-type 1, and emm-type 1 among invasive isolates of group A streptococci. The emm-type 28 associated with T-type 28 was frequently observed in non-invasive isolates. A prospective study is being conducted to update the prevalence of the different emm-types in France, which will be of importance for the development of future vaccines.

Published
2004

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