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Your search keyword '"Maria S. Brown"' showing total 7 results
Start Over Author "Maria S. Brown" Topic stereochemistry
7 results on '"Maria S. Brown"'

3. Biosynthesis of the Shikimate-derived Starter Unit of the Immunosuppressant Ascomycin: Stereochemistry of the 1,4-Conjugate Elimination

Author

Sandeep Handa, Heinz G. Floss, Kevin A. Reynolds, Hamish A. I. McArthur, Kimberlee K. Wallace, and Maria S. Brown

Subjects
Pharmacology, Molecular Structure, Stereochemistry, Streptomycetaceae, Stereoisomerism, Metabolism, Biology, biology.organism_classification, Streptomyces, Tacrolimus, chemistry.chemical_compound, Biosynthesis, chemistry, Drug Discovery, medicine, Ascomycin, Streptomyces hygroscopicus, Immunosuppressive Agents, medicine.drug, Conjugate
Published
1997

4. Production of Tuberactinamine A by Streptomyces griseoverticillatus var. tuberacticus NRRL 3482 Fed with (S)-2-Aminoethyl-L-cysteine

Author

T. Kevin Murphy, Brook Knight Morse, John W. Wong, Richard Gerald Wax, Hamish A. I. McArthur, Gagne John William, Adam A. Smogowicz, Matt H. Narrol, Maria S. Brown, David Austen Perry, and Ellen L. McCormick

Subjects
Protein Synthesis Inhibitors, Pharmacology, biology, Streptomycetaceae, Stereochemistry, biology.organism_classification, Streptomyces, chemistry.chemical_compound, Biosynthesis, chemistry, Fermentation, Drug Discovery, Botany, Enviomycin, Cysteine, Actinomycetales, Bacteria, Antibacterial agent
Published
1997

5. Production of 6-deoxy-13-cyclopropyl-erythromycin B by Saccharopolyspora erythraea NRRL 18643

Author

Hamish A. I. McArthur, Ellen L. McCormick, Mike Pacey, Thomas N. O'Connell, John C. Ruddock, John P. Dirlam, Paul A. Murphy, Maria S. Brown, Brook Knight Morse, Richard Gerald Wax, and Dianne M. Rescek

Subjects
Cyclopropanes, Pseudonocardiaceae, Magnetic Resonance Spectroscopy, Stereochemistry, Carboxylic acid, Microbial Sensitivity Tests, chemistry.chemical_compound, Drug Discovery, Antibacterial agent, Pharmacology, chemistry.chemical_classification, biology, ATP synthase, Molecular Structure, biology.organism_classification, Anti-Bacterial Agents, Erythromycin, 6-deoxy-13-cyclopropyl-erythromycin B, Aglycone, chemistry, Biochemistry, biology.protein, Saccharopolyspora erythraea, Macrolides, Bacteria, Saccharopolyspora
Abstract

Cyclopropane carboxylic acid was fed to Saccharopolyspora erythraea NRRL 18643 (6-deoxyerythromycin producer), resulting in the production of 6-deoxy-13-cyclopropyl-erythromycin B. These studies provide further evidence that deoxyerythronolide B synthase has a relaxed specificity for the starter unit.

Published
1999

6. Stereochemical Analyses of the Streptomyces hygroscopicus var. ascomyceticus Type-II Dehydroquinate Dehydratase and Evidence for a Role of the Enzyme in the Biosynthesis of the Shikimate-Derived Moiety of Ascomycin

Author

Claudio D. Denoya, Maria S. Brown, Hamish A. I. McArthur, Kevin A. Reynolds, Yuko M. Lindsay, and Galina Florova

Subjects
chemistry.chemical_classification, biology, Stereochemistry, Chemistry, Organic Chemistry, biology.organism_classification, chemistry.chemical_compound, Enzyme, Biochemistry, Biosynthesis, Dehydratase, medicine, Moiety, Ascomycin, Streptomyces hygroscopicus, medicine.drug
Published
1998

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