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It has come to be the accepted opinion that the phagocytic cells of the tissues, which have been designated as clasmatocytes, macrophages or histiocytes, and the large mononuclear elements of the b...

The observations reported in the preceding communication1 led us to consider the possibility that the phagocytic cells occurring in peritoneal exudates might be separated into the same two groups that were found in the spleen. It has been possible to demonstrate that this is true. A normal rabbit was given intraperitoneally 25 cc. of whole blood, which had been removed by a sterile puncture from the heart of another rabbit, and, after 24 hours, samples of the exudate were removed and studied. Another injection was then given and the examination repeated at the end of the second 24 hours. This procedure was repeated at 24 hour intervals over as long a time as was desired. Some of the experiments were carried out on rabbits whose blood-cells had been carefully matched, while in other instances animals were selected in which the serum of one agglutinated the red blood-cells of the other and vice versa. The exudate was studied with neutral red and Janus green in vital-dye films. It has been shown2 that the fi...