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Background: Social determinants of health (SDH) play an important role in health outcomes. This study sought to evaluate the effectiveness of a SDH screening and health-related social needs (HRSNs) referral program in an emergency department (ED) setting with adult Medicaid beneficiaries., Methods: Between November 2016 and March 2017 we enrolled adult Medicaid patients in a prospective cohort study. Research assistants (RAs) completed an SDH screening survey with participants and asked them if they needed assistance with HRSNs related to medical, behavioral health, wellness, housing, food, legal and job training issues. RAs referred participants to community-based organizations (CBO) for their top three HRSNs. Patients referred to at least one CBO were phoned a month later to determine whether their HRSN was addressed and CBOs also reported their assistance rates within four months of the ED visit., Results: Of the 505 patients enrolled, 69% were female, 82% completed high school, and 57% reported working. Most participants (85%) requested assistance for at least one HRSN. Almost half (44%) received referrals to three different agencies. Help with housing (70%), medical issues (51%), and finding food (42%) were the most common. Among the 430 subjects referred to ≥1 agency, 76% completed the follow-up interview. Few patients reported receiving help from the referral agencies (5% for a wellness program to 15% for medical services). Referral agencies generally reported even lower assistance rates (0% for job training to 17% for medical services)., Conclusion: The majority of adult Medicaid patients treated in our ED wanted assistance with one or more HRSN. The passive referral system we implemented resulted in few patients receiving assistance from the referral agency, regardless of whether measured by self-report or by agency., Competing Interests: Declaration of Competing Interest No commercial conflicts of interest., (Copyright © 2021 Elsevier Inc. All rights reserved.)

Background: Medication adherence (MA) is critical to successful chronic disease management. It is not clear how social determinants of health (SDH) impact MA. We conducted a systematic review and meta-analysis to summarize the evidence on the relationship between SDH and MA., Methods: We conducted a systematic review of the literature using a Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) format. A literature search was performed using three databases: PubMed, Scopus, and Cochrane Clinical Trials Register in December of 2018. Included studies were completed in the USA, included adults aged 18 years and older, measured at least one social determinant of health, and medication adherence was the primary outcome measure. Data from included full texts were independently extracted using a standardized data extraction form. We then conducted a meta-analysis and pooled the odds ratios from the included studies for each social determinant as well as for all SDH factors collectively., Results: A total of 3137 unduplicated abstracts were identified from our database searches. A total of 173 were selected for full text review after evaluating the abstract. A total of 29 articles were included for this systematic review. Economic-related SDH factors and MA were mostly commonly examined. The meta-analysis revealed a significant relationship between food insecurity (aOR = 0.56; 95% CI 0.42-0.7), housing instability (aOR = 0.64; 95% CI 0.44-0.93), and social determinants overall (aOR = 0.75; 95% CI 0.65-0.88) and medication adherence., Discussion: Food insecurity and housing instability most consistently impacted medication adherence. Although included studies were heterogenous and varied widely in SDH and MA measurements, adverse social determinants overall were significantly associated with lower MA. The relationship between SDH and MA warrants more attention and research by health care providers and policymakers.

Objective: To develop distinct social risk profiles based on social determinants of health (SDH) information and to determine whether these social risk groups varied in terms of health, health care utilization, and costs., Methods: We prospectively enrolled 8943 beneficiaries insured by the District of Columbia Medicaid program between September 2017 and December 2018. Participants completed a SDH survey and we obtained their Medicaid claims data for a 2-year period before study enrollment. We used latent class analysis (LCA) to identify distinct social risk profiles based on their SDH responses. We assessed the relationship among different SDH as well as the relationship among the social risk classes and health, health care use and costs., Results: The majority of SDH were moderately to strongly correlated with one another. LCA yielded 4 distinct social risk groups. Group 1 reported the least social risks with the most employed. Group 2 was distinguished by financial strain and housing instability with fewer employed. Group 3 were mostly unemployed with limited car and internet access. Group 4 had the most social risks and most unemployed. The social risk groups demonstrated meaningful differences in health, acute care utilization, and health care costs with group 1 having the best health outcomes and group 4 the worst (P<0.05)., Conclusions: LCA is a practical method of aggregating correlated SDH data into a finite number of distinct social risk groups. Understanding the constellation of social challenges that patients face is critical when attempting to address their social needs and improve health outcomes., Competing Interests: The authors declare no conflict of interest., (Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.)

Background: Medication adherence (MA) is critical to successful chronic disease management. It is not clear how social determinants of health (SDH) impact MA. We conducted a systematic review and meta-analysis to summarize the evidence on the relationship between SDH and MA. Methods: We conducted a systematic review of the literature using a Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) format. A literature search was performed using three databases: PubMed, Scopus, and Cochrane Clinical Trials Register in December of 2018. Included studies were completed in the USA, included adults aged 18 years and older, measured at least one social determinant of health, and medication adherence was the primary outcome measure. Data from included full texts were independently extracted using a standardized data extraction form. We then conducted a meta-analysis and pooled the odds ratios from the included studies for each social determinant as well as for all SDH factors collectively. Results: A total of 3137 unduplicated abstracts were identified from our database searches. A total of 173 were selected for full text review after evaluating the abstract. A total of 29 articles were included for this systematic review. Economic-related SDH factors and MA were mostly commonly examined. The meta-analysis revealed a significant relationship between food insecurity (aOR = 0.56; 95% CI 0.42–0.7), housing instability (aOR = 0.64; 95% CI 0.44–0.93), and social determinants overall (aOR = 0.75; 95% CI 0.65–0.88) and medication adherence. Discussion: Food insecurity and housing instability most consistently impacted medication adherence. Although included studies were heterogenous and varied widely in SDH and MA measurements, adverse social determinants overall were significantly associated with lower MA. The relationship between SDH and MA warrants more attention and research by health care providers and policymakers. [ABSTRACT FROM AUTHOR]