1. Recurrent MVD mutation in European patients with disseminated porokeratosis.
- Author
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Saleva‐Stateva, M., Technau‐Hafsi, K., Frommherz, L., Grüninger, G., Jägle, S., Dourmishev, L., Miteva, L., Fischer, J., and Has, C.
- Subjects
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SKIN cancer , *BASAL cell carcinoma - Abstract
Pathogenetic-based topical treatment with statins that target the mevalonate pathway and cholesterol biosynthesis was recently shown to be effective in disseminated porokeratosis.8 Here we performed molecular genetic analysis of skin samples of eight patients with disseminated porokeratosis. (a) Before treatment, the patient presented porokeratotic lesions on the arms and legs. Two novel SSH1 mutations in Chinese patients with disseminated superficial actinic porokeratosis and immunohistochemical analysis of anti-Slingshot homolog 1 antibody in one typical patient. [Extracted from the article]
- Published
- 2021
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