10 results on '"Cahill, Anne Marie"'
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2. Large scalp venous malformation in a pediatric patient managed with sclerotherapy and surgery: a case report and review of literature.
- Author
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Punchak MA, Hollawell ML, Viaene AN, Cahill AM, Storm PB, Madsen PJ, and Tucker AM
- Subjects
- Adolescent, Infant, Newborn, Humans, Child, Male, Scalp, Treatment Outcome, Sclerotherapy, Vascular Malformations surgery
- Abstract
Background: Venous malformations (VMs) are slow-flow vascular anomalies present at birth that enlarge during adolescence, subsequently causing thrombosis, hemorrhage, and pain., Case Presentation: We describe a case of an adolescent male presenting with a large scalp venous malformation. Given the size and location of the lesion, a hybrid approach employing both sclerotherapy and surgical resection was utilized. The VM was successfully removed without complication., Conclusion: A hybrid approach is a safe and effective treatment consideration for immediate management of large venous malformation in higher-risk locations., (© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2023
- Full Text
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3. Methemoglobinemia in an Infant After Sclerotherapy With High-Dose Doxycycline.
- Author
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Coughlin K, Flibotte J, Cahill AM, Osterhoudt K, Hedrick H, and Vrecenak J
- Subjects
- Humans, Infant, Newborn, Male, Sclerotherapy methods, Anti-Bacterial Agents adverse effects, Doxycycline adverse effects, Methemoglobinemia chemically induced, Methemoglobinemia diagnostic imaging, Sclerotherapy adverse effects
- Abstract
Methemoglobinemia occurs when the heme moiety of hemoglobin (Hb) is oxidized from the ferrous to ferric state, leading to impairments in oxygen transport and delivery. Methemoglobinemia is rare in pediatric patients but has been described in the setting of congenital abnormalities in the Hb structure, inherited enzyme deficiencies, oxidative Hb injury in response to illness, and oxidative Hb injury due to toxicants. We present a 1-week-old infant born with a cervical lymphangioma who developed persistent desaturations that were unresponsive to oxygen after sclerotherapy with doxycycline. Arterial blood gas revealed a high Pao
2 despite low saturations being found on pulse oximetry and a methemoglobin level that was found to be elevated. Further sclerotherapy was discontinued, the saturations eventually normalized, and the methemoglobin level decreased. This is a novel report of sclerotherapy with doxycycline associated with the development of methemoglobinemia., Competing Interests: POTENTIAL CONFLICT OF INTEREST: The authors have indicated they have no potential conflicts of interest to disclose., (Copyright © 2019 by the American Academy of Pediatrics.)- Published
- 2019
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4. Percutaneous Treatment of Lymphatic Malformations.
- Author
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Acord M, Srinivasan AS, and Cahill AM
- Subjects
- Child, Preschool, Female, Humans, Infant, Infant, Newborn, Lymphatic Abnormalities diagnostic imaging, Lymphatic Abnormalities physiopathology, Lymphatic System diagnostic imaging, Lymphatic System physiopathology, Magnetic Resonance Imaging, Male, Predictive Value of Tests, Risk Factors, Sclerosing Solutions adverse effects, Sclerotherapy adverse effects, Treatment Outcome, Lymphatic Abnormalities therapy, Lymphatic System abnormalities, Sclerosing Solutions administration & dosage, Sclerotherapy methods
- Abstract
Lymphatic malformations are slow-flow vascular anomalies composed of dilated lymphatic channels and cysts of varying sizes. Percutaneous treatments, particularly sclerotherapy, play an important role in the treatment of these lesions, often obviating the need for surgical intervention. Owing to the complex nature of these lesions, a multidisciplinary approach should be used to guide diagnosis and management. This submission focuses on the workup and treatment of pediatric lymphatic malformations at our institution, with a focus on sclerotherapy. Therapeutic outcomes and the management of postprocedural complications are also discussed., (Copyright © 2016 Elsevier Inc. All rights reserved.)
- Published
- 2016
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5. Percutaneous sclerotherapy in neonatal and infant head and neck lymphatic malformations: a single center experience.
- Author
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Cahill AM, Nijs E, Ballah D, Rabinowitz D, Thompson L, Rintoul N, Hedrick H, Jacobs I, and Low D
- Subjects
- Airway Obstruction etiology, Airway Obstruction therapy, Anemia, Hemolytic chemically induced, Doxycycline administration & dosage, Doxycycline adverse effects, Ethanol administration & dosage, Ethanol adverse effects, Ethanol therapeutic use, Female, Head and Neck Neoplasms complications, Head and Neck Neoplasms diagnostic imaging, Head and Neck Neoplasms pathology, Horner Syndrome chemically induced, Humans, Hypoglycemia chemically induced, Infant, Infant, Newborn, Injections, Instillation, Drug, Lymphangioma, Cystic complications, Lymphangioma, Cystic diagnostic imaging, Lymphangioma, Cystic pathology, Lymphatic Abnormalities complications, Lymphatic Abnormalities diagnostic imaging, Lymphatic Abnormalities pathology, Magnetic Resonance Imaging, Male, Radiography, Interventional, Retrospective Studies, Sclerosing Solutions administration & dosage, Sclerosing Solutions adverse effects, Sclerotherapy adverse effects, Sodium Tetradecyl Sulfate administration & dosage, Sodium Tetradecyl Sulfate adverse effects, Sodium Tetradecyl Sulfate therapeutic use, Tomography, X-Ray Computed, Treatment Outcome, Ultrasonography, Doxycycline therapeutic use, Head and Neck Neoplasms therapy, Lymphangioma, Cystic therapy, Lymphatic Abnormalities therapy, Sclerosing Solutions therapeutic use, Sclerotherapy methods
- Abstract
Purpose: To evaluate the clinical outcomes of percutaneous sclerotherapy for congenital head and neck lymphatic malformations in our institution., Materials and Methods: Over a 7-year period, 17 children (10 M, 7 F) mean age 5.8 months (5 days to 13 months) underwent 49 sclerotherapy procedures for congenital head and neck malformations. The imaging and clinical records were reviewed for each patient. Ten of 17 had macrocystic disease; 7 of 17 had microcystic disease. Imaging response was categorized by volume reductions of 0% to 25%, 25% to 50%, 50% to 75%, or 75% to 100%. A concentration of 10 mg/mL doxycycline was used routinely via catheter in 3 instillations with a dose range of 50 to 500 mg per session as per our standard protocol in 17 of 17 patients. In more recent patients, systemic doxycycline levels were obtained after instillations. Additional treatments included direct injection doxycycline (10/17), instillation of absolute ethanol (7/17) or sodium tetradecyl sulfate (4/17), or a combination of these methods., Results: Imaging improvement of ≥ 76% was noted in 11 of 17. Of these, 8 of 11 had macrocystic disease. Four of 17 had 51% to 75% resolution, of which 3/4 were mixed. Two of 17 children had 25% to 50% resolution with a mixed lesion. Seven of 49 peri-procedural complications: hemolytic anemia in 2 infants, hypoglycemic and metabolic acidosis in 3 neonates aged 7 to 10 days, transient hypotension during absolute alcohol instillation in 1 neonate, and self-limiting skin excoriation secondary to peri-catheter leakage of doxycycline in one neonate. Neonates prone to these systemic complications had doxycycline doses of greater than 250 mg and resulted in serum levels of >5 μg/mL but as high as 21 μg/mL. Delayed neural complications occurred in 7 of 49 procedures, Horner's syndromes in 4 of 49 procedures, transient left lip weakness in 1 of 49 procedures, right facial nerve palsy in 1 of 49 procedures, and transient left hemidiaphragm paralysis in 1/49 procedures., Conclusion: Our experience with catheter directed doxycycline sclerotherapy provides excellent results for large macrocystic head and neck lymphatic malformations. Microcystic and mixed lesions continue to provide a therapeutic challenge., (Copyright © 2011 Elsevier Inc. All rights reserved.)
- Published
- 2011
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6. Bowel perforation following percutaneous sclerotherapy of an intra-abdominal lymphatic malformation
- Author
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Durand, Rachelle E., Heye, Pascal, Cahill, Anne Marie, Laje, Pablo, and Srinivasan, Abhay S.
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- 2022
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7. Early experience with X-ray magnetic resonance fusion for low-flow vascular malformations in the pediatric interventional radiology suite
- Author
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Hwang, Tiffany J., Girard, Erin, Shellikeri, Sphoorti, Setser, Randolph, Vossough, Arastoo, Ho-Fung, Victor, and Cahill, Anne Marie
- Published
- 2016
- Full Text
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8. Pediatric Vascular Malformations: Pathophysiology, Diagnosis, and the Role of Interventional Radiology
- Author
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Cahill, Anne Marie and Nijs, Els Louisa Francine
- Published
- 2011
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9. Balloon occlusion as an adjunctive technique during sclerotherapy of Puig's classified advanced venous malformations.
- Author
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Sundararajan, Sri Hari, Ranganathan, Srirajkumar, Shellikeri, Sphoorti, Srinivasan, Abhay, Low, David W, Pukenas, Bryan, Hurst, Robert, and Cahill, Anne Marie
- Subjects
SUBCLAVIAN veins ,TRANSLUMINAL angioplasty ,INSTITUTIONAL review boards ,THERAPEUTIC embolization ,BALLOON occlusion ,TREATMENT effectiveness ,SCLEROTHERAPY ,BLOOD-vessel abnormalities ,QUESTIONNAIRES ,QUALITY of life ,JUGULAR vein ,POPLITEAL vein - Abstract
Objective: Puig types 2 through 4 venous malformations (VMs) are challenging to treat with sclerotherapy given their robust systemic outflow. Endovenous balloon occlusion offers a means of temporarily occluding systemic venous outflow to allow for more complete sclerotherapy. This study reviews our experience of implementing this technique in patients with Puig advanced (types 2 through 4) VMs. Methods: An IRB approved review of treated venous malformations from 2013–2016 revealed 10 patients fitting inclusion criteria. Patient demographics, pre-procedural imaging, intra-procedural technical parameters, and post-procedural follow-up outcomes were recorded. All patients underwent temporary balloon occlusion of a systemic or major draining vein during sclerotherapy. Embolic agents included n-butyl cyanoacrylate glue, sodium tetradecyl sulfate foam, and coils. Standard 5 French angioplasty balloons ranged from 4 to 8 mm diameter and 2 to 8 cm length depending on vessel requiring occlusion. All patients underwent minimum 3-year follow-up questionnaire administration re-assessing resolution of lesion symptomology and post-procedural quality of life (QoL) measures. Results: Of the 10 VMs treated, 2 were Type 2, 6 were Type 3, and 2 were Type 4. More than one sclerotherapy session was required in 7/10 patients (mean: 2, range: 1–4). Most common sites of VM systemic drainage included subclavian, popliteal, internal/external jugular, and basilic veins. All patients had no indication for further sclerotherapy following adjunctive balloon occlusion. No non-target embolization or immediate post-procedural complications occurred. Follow-up questionnaires (mean interval: 3 years 6 months, range: 3 years–3 years 11 months) confirmed the persistence of embolization effects, improved QoL, and no additional sclerotherapy sessions for all patients in the cohort. Conclusions: Endovenous balloon occlusion as an adjunct to sclerotherapy can be considered when treating patients with types 2–4 venous malformations. This technique lowers the risk of non-target systemic venous embolization, allowing for operator-driven deeper intralesional sclerosant penetration and subsequently maintained treatment efficacy. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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10. Reduced-dose C-arm computed tomography applications at a pediatric institution.
- Author
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Acord, Michael, Shellikeri, Sphoorti, Vatsky, Seth, Srinivasan, Abhay, Krishnamurthy, Ganesh, Keller, Marc, Cahill, Anne, Keller, Marc S, and Cahill, Anne Marie
- Subjects
COMPUTED tomography ,DETECTORS ,RADIOLOGY ,SCLEROTHERAPY ,SACROILIAC joint - Abstract
Background: Reduced-dose C-arm computed tomography (CT) uses flat-panel detectors to acquire real-time 3-D images in the interventional radiology suite to assist with anatomical localization and procedure planning.Objective: To describe dose-reduction techniques for C-arm CT at a pediatric institution and to provide guidance for implementation.Materials and Methods: We conducted a 5-year retrospective study on procedures using an institution-specific reduced-dose protocol: 5 or 8 s Dyna Rotation, 248/396 projection images/acquisition and 0.1-0.17 μGy/projection dose at the detector with 0.3/0.6/0.9-mm copper (Cu) filtration. We categorized cases by procedure type and average patient age and calculated C-arm CT and total dose area product (DAP).Results: Two hundred twenty-two C-arm CT-guided procedures were performed with a dose-reduction protocol. The most common procedures were temporomandibular and sacroiliac joint injections (48.6%) and sclerotherapy (34.2%). C-arm CT was utilized in cases of difficult percutaneous access in less common applications such as cecostomy and gastrostomy placement, foreign body retrieval and thoracentesis. C-arm CT accounted for between 9.9% and 80.7% of the total procedural DAP.Conclusion: Dose-reducing techniques can preserve image quality for intervention while reducing radiation exposure to the child. This technology has multiple applications within pediatric interventional radiology and can be considered as an adjunctive imaging tool in a variety of procedures, particularly when percutaneous access is challenging despite routine fluoroscopic or ultrasound guidance. [ABSTRACT FROM AUTHOR]- Published
- 2017
- Full Text
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