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The article discusses the importance of preregistration in animal research and the benefits it can bring to the field. Animal studies are crucial in biomedical research, including cardiology, but concerns have been raised about their validity and reporting quality. Preregistration involves recording a protocol before starting experiments, which increases transparency, reduces biases, and provides a complete overview of all animal studies. The article introduces preclinicaltrials.eu, the first platform dedicated to animal study protocol preregistration, and highlights its features and benefits. Despite international recognition, the number of registered protocols remains relatively low, and the article calls for the scientific community to embrace and require preregistration to improve the rigor and quality of preclinical research. [Extracted from the article]

In 2018, the first registry dedicated to preregistration of animal study protocols was launched. Despite international support, the overall number of (pre)registered protocols is still low, illustrating the need for pushing the preregistration agenda among researchers and policymakers. This Community Page article presents a 3-year evaluation of the first platform dedicated to preregistration of animal studies, www.preclinicaltrials.eu, and comparable platforms, encouraging the scientific community to embrace preregistration in a move towards more effective animal research. [ABSTRACT FROM AUTHOR]