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1. [Relationship between cytochemical activity of leukocytes and autorosette formation phenomenon and its clinical significance in patients with leptospirosis].

Author

Subich MG, Avdeeva MG, and Moĭsova DL

Subjects
Acid Phosphatase blood, Adolescent, Adult, Aged, Alkaline Phosphatase blood, Female, Histocytochemistry, Humans, Leukocytes metabolism, Male, Middle Aged, Weil Disease diagnosis, Weil Disease metabolism, Leukocytes immunology, Rosette Formation, Weil Disease immunology
Abstract

The content of autorosettes in the peripheral blood forming from red cells round neutrophils and monocytes was found increased during the acute period of icterohemorrhagic leptospirosis. Autorosette-forming cells are characterized by a high activity of alkaline and acid phosphatases and low NBT-test values. The content of autorosettes directly correlates with the disease severity, bilirubin level, and presence of anemia. Assessment of autorosette-forming cells in patients with leptospirosis may be used as an additional test for evaluating the severity of intoxication, disease course, and for predicting the complications and disease outcome.

Published
1997

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