1. The profile analysis of circular RNAs in human placenta of preeclampsia.
- Author
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Zhou W, Wang H, Wu X, Long W, Zheng F, Kong J, and Yu B
- Subjects
- Computational Biology, Female, Gene Expression Profiling, Humans, Plasma chemistry, Pregnancy, RNA genetics, RNA, Circular, Real-Time Polymerase Chain Reaction, Sequence Analysis, RNA, Placenta pathology, Pre-Eclampsia pathology, RNA analysis
- Abstract
Impact Statement: The abnormal expression of many regulatory factors may be involved in the development of PE. circRNAs are proved to have a series of important biological functions; however, reports about circRNA and PE are rare. In this work, we evaluated the profile analysis of circRNAs in human placenta of PE by RNA-seq and found some newly differentially expressed circRNAs which might be involved in PE. Combined with bioinformatics analysis, their possible functions were preliminarily discussed.
- Published
- 2018
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