1. Vitamin B12 deficiency presenting as pseudo-thrombotic microangiopathy: a case report and literature review
- Author
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Fahmawi Y, Campos Y, Khushman M, Alkharabsheh O, Manne A, Zubair H, Haleema S, Polski J, and Bessette S
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Vitamin B12 deficiency ,Pseudo-thrombotic microangiopathy ,Schistocytes ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Yazan Fahmawi,1 Yesica Campos,1 Moh’d Khushman,2 Omar Alkharabsheh,2 Ashish Manne,2 Haseeb Zubair,2 Saadia Haleema,3 Jacek Polski,3 Sabrina Bessette11Department of Internal Medicine, University of South Alabama, Mobile, AL, USA; 2Department of Hematology-Oncology, Mitchell Cancer Institute, University of South Alabama, Mobile, AL, USA; 3Department of Pathology, University of South Alabama, Mobile, AL, USACorrespondence: Yazan FahmawiDepartment of Internal Medicine, University of South Alabama, 2451 USA Medical Center Drive, Mobile, AL 36617, USATel +1 251 471 7891Fax +1 251 470 1652Email yfahmawi@health.southalabama.eduAbstract: Pseudo-thrombotic microangiopathy (pseudo-TMA) is a recognized, yet uncommon, clinical presentation of vitamin B12 deficiency. Patients with pseudo-TMA present with microangiopathic hemolytic anemia (MAHA), thrombocytopenia and schistocytes. They are often misdiagnosed as thrombotic thrombocytopenia purpura (TTP) and receive unnecessary therapy. Here, we report a case of a 60-year-old male who presented with thrombocytopenia and normocytic normochromic anemia. Anemia work-up was remarkable for severe B12 deficiency (
- Published
- 2019