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Your search keyword '"treatment rebound"' showing total 2 results
Start Over Descriptor "treatment rebound" Topic ritonavir
2 results on '"treatment rebound"'

1. Virologic and Immunologic Characterization of Coronavirus Disease 2019 Recrudescence After Nirmatrelvir/Ritonavir Treatment

Author

Carlin, Aaron F, Clark, Alex E, Chaillon, Antoine, Garretson, Aaron F, Bray, William, Porrachia, Magali, Santos, AsherLev T, Rana, Tariq M, and Smith, Davey M

Subjects
Lung, Infectious Diseases, Prevention, Pneumonia & Influenza, Emerging Infectious Diseases, Immunization, Vaccine Related, Pneumonia, Biodefense, Good Health and Well Being, Humans, COVID-19, SARS-CoV-2, Ritonavir, COVID-19 Drug Treatment, treatment rebound, COVID-19 recrudescence, nirmatrelvir, Omicron, Biological Sciences, Medical and Health Sciences, Microbiology
Abstract

We isolated a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BA.2 variant from a person with coronavirus disease 2019 recrudescence after nirmatrelvir/ritonavir treatment. Antiviral sensitivity and neutralizing antibody testing were performed with both parental SARS-CoV-2 and multiple variants of concern. We found that neither nirmatrelvir resistance nor absence of neutralizing immunity was a likely cause of the recrudescence.

Published
2023

2. Virologic and Immunologic Characterization of Coronavirus Disease 2019 Recrudescence After Nirmatrelvir/Ritonavir Treatment

Author

Aaron F Carlin, Alex E Clark, Antoine Chaillon, Aaron F Garretson, William Bray, Magali Porrachia, AsherLev T Santos, Tariq M Rana, and Davey M Smith

Subjects
Microbiology (medical), Ritonavir, SARS-CoV-2, Omicron, nirmatrelvir, Prevention, COVID-19, Pneumonia, Biological Sciences, Medical and Health Sciences, Microbiology, COVID-19 Drug Treatment, Vaccine Related, Infectious Diseases, Emerging Infectious Diseases, Good Health and Well Being, Biodefense, COVID-19 recrudescence, Pneumonia & Influenza, Humans, treatment rebound, Immunization, Lung
Abstract

We isolated a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BA.2 variant from a person with coronavirus disease 2019 recrudescence after nirmatrelvir/ritonavir treatment. Antiviral sensitivity and neutralizing antibody testing were performed with both parental SARS-CoV-2 and multiple variants of concern. We found that neither nirmatrelvir resistance nor absence of neutralizing immunity was a likely cause of the recrudescence.

Published
2023

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