1. Experimental infection of white-tailed deer with rinderpest virus.
- Author
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Hamdy FM, Dardiri AH, Ferris DH, and Breese SS Jr
- Subjects
- Animals, Blood microbiology, Digestive System pathology, Lymph Nodes pathology, Respiratory Tract Infections pathology, Rinderpest microbiology, Rinderpest pathology, Rinderpest virus immunology, Rinderpest virus isolation & purification, Rinderpest virus ultrastructure, Deer, Rinderpest etiology
- Abstract
White-tailed deer (Odocoileus virginianus) succumbed to experimental infection with virulent rinderpest (RP) virus that was also lethal to cattle and goats. The deer developed clinical signs typical of RP and died 5 and 6 days post-inoculation. Infection was confirmed by recovery of virus from blood before death, from lymph node tissue after necropsy, and demonstration of specific complement fixing antigen in those tissues. Electron micrographs of infected Vero cell cultures revealed extracellular virions and intracytoplasmic and intranuclear inclusions made of randomly distributed fibrillar strands.
- Published
- 1975
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