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A new method for the synthesis of highly substituted naphthyridine-based polyheteroaromatic compounds in high yields proceeds through rhodium(III)-catalyzed multiple CH bond cleavage and CC and CN bond formation in a one-pot process. Such highly substituted polyheteroaromatic compounds have attracted much attention because of their unique π-conjugation, which make them suitable materials for organic semiconductors and luminescent materials. Furthermore, a possible mechanism, which involves multiple chelation-assisted ortho CH activation, alkyne insertion, and reductive elimination, is proposed for this transformation. [ABSTRACT FROM AUTHOR]

Rhodium-catalyzed C–H functionalizationshave been usedfor ortho-directed additions of 2-arylpyridines and(hetero)aryl-substituted pyrimidines, isoquinolines, and benzo[h]quinolones to cyclic imines. The resulting amino-functionalizedproducts are formed in good to high yields. [ABSTRACT FROM AUTHOR]

Two new rhodium-catalyzed oxidative couplings between sulfoximine derivatives and alkenes by regioselective CH activation, affording ortho-olefinated (Heck-type) products, are reported. A synthetic application of the ortho-alkenylated products into the corresponding cyclic derivatives has been demonstrated, and a mechanistic rational for the rhodium catalysis is presented. [ABSTRACT FROM AUTHOR]

Revitalisierung durch Sauerstoff: Eine Rhodium(III) ‐ katalysierte Sequenz aus oxidativer C ‐ H/N ‐ H ‐ Aktivierung und Anellierung eröffnet den Zugang zu substituierten 1,2 ‐ Benzothiazinen ausgehend von leicht verfügbaren NH ‐ Sulfoximinen und Alkinen (siehe Schema; Cp*=C5Me5). Das Oxidationssystem besteht aus molekularem Sauerstoff und einer katalytischen Menge Fe(OAc)2. [ABSTRACT FROM AUTHOR]

Described herein is a convenient and highly regioselective synthesis of substituted isoquinoline derivatives from various aromatic ketoximes and alkynes via a one-pot, rhodium-catalyzed C-H bond activation. In addition, tetrahydroquinoline derivatives are formed in good yields from 2-arylidene-1-cyclohexanone oximes possessing an exocyclic double bond and from tetrahydroxanthone oximes. A possible mechanism is proposed that involves chelation-assisted C-H activation via oxidative addition of Rh(I) to an ortho-C-H bond, insertion of the alkyne, reductive elimination, intramolecular electrocyclization, and aromatization. This mechanism is supported by isolation of the ortho-alkenylation products 7p and 7q. Also described herein is an example of an iridium-catalyzed actIvation of an sp3 C—H bond. [ABSTRACT FROM AUTHOR]

Rhodium-catalyzed directed CH-functionalizations are used in hydroarylations of heterobicyclic alkenes with NH-sulfoximines. [ABSTRACT FROM AUTHOR]

Rh-catalyzed reaction of N-hydroxybenzamidines with an excess of internal alkynes and an excess of Cu(OAc)2 as the oxidant is described to produce polyhetarenes in good yields. [ABSTRACT FROM AUTHOR]

The article presents chemical equations related to the article "Directed Additions of 2-Arylpyridines and Related Substrates to Cyclic Imines Through Rhodium-Catalyzed C?H Functionalization" by K. Parthasarathy and others, published in the periodical "Organic Letters" in 2014.

The one-pot synthesis of substituted phenanthridinones involves a rhodium-catalyzed dual C-H bond activation and annulation reactions. [ABSTRACT FROM AUTHOR]

Rhodium(III)-catalyzed ortho brominations and iodinations of N-acylsulfoximines by C-H bond activations have been developed. Subsequent product functionalizations involving cross-coupling reactions provide alkynylated sulfoximine derivatives and benzothiazines with wide potential for further synthetic applications. [ABSTRACT FROM AUTHOR]

Rh-catalyzed oxidative cyclocondensation of NH-sulfoximines and internal alkynes provides an efficient synthesis of 1,2-benzothiazines. [ABSTRACT FROM AUTHOR]