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A new Rh(iii)-catalyzed oxidative bicyclization through C–H functionalization is presented. This reaction allows the selective assembly of diverse benzo[g]indoles from 4-arylbut-3-yn-1-amines and internal alkynes via a sequence of aromatic C(sp2)–H functionalization, cyclodimerization and nucleophilic cyclization. [ABSTRACT FROM AUTHOR]

This study describes a new rhodium(III)-catalyzed [3+2] annulation of 5-aryl-2,3-dihydro-1H-pyrroles with internal alkynes using a Cu(OAc)2 oxidant for building a spirocyclic ring system, which includes the functionalization of an aryl C(sp2)H bond and addition/protonolysis of an alkene CC bond. This method is applicable to a wide range of 5-aryl-2,3-dihydro-1H-pyrroles and internal alkynes, and results in the assembly of the spiro[indene-1,2′-pyrrolidine] architectures in good yields with excellent regioselectivities. [ABSTRACT FROM AUTHOR]

A new Rh-catalyzed reaction of 4-arylbut-3-yn-1-amines (I) with symmetrically 1,2-disubstituted acetylenes (II) gives rise to cross-bicyclization products (III), whilst the use of unsymmetrically disubstituted alkynes (IV) leads to a mixture of regioisomers (V) and (VI). [ABSTRACT FROM AUTHOR]