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3 results on '"Goff MJ"'

1. Diagnostic and therapeutic challenges. Viral keratitis in the left eye managed by antiviral drops and a retrobulbar injection of 20 mg of gentamicin.

Author

Yin X, Ji S, Yuan R, Liu S, Chen S, Lanzetta P, Tarantini A, Goff MJ, and Townley JR

Subjects
Adult, Anti-Bacterial Agents adverse effects, Anti-Bacterial Agents therapeutic use, Blindness chemically induced, Blindness diagnosis, Corneal Ulcer virology, Drug Therapy, Combination, Eye Injuries, Penetrating diagnosis, Eye Injuries, Penetrating drug therapy, Fluorescein Angiography, Gentamicins therapeutic use, Humans, Injections adverse effects, Male, Needlestick Injuries drug therapy, Ophthalmic Solutions administration & dosage, Retinal Diseases chemically induced, Antiviral Agents administration & dosage, Corneal Ulcer drug therapy, Eye Infections, Viral drug therapy, Gentamicins adverse effects, Needlestick Injuries diagnosis, Retina drug effects, Retina injuries, Retinal Diseases diagnosis
Published
2008
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2. The natural history of pigment epithelial detachment associated with central serous chorioretinopathy.

Author

Mudvari SS, Goff MJ, Fu AD, McDonald HR, Johnson RN, Ai E, and Jumper JM

Subjects
Adult, Aged, Choroid Diseases complications, Choroid Diseases drug therapy, Exudates and Transudates, Female, Fluorescein Angiography, Glucocorticoids therapeutic use, Humans, Male, Middle Aged, Retinal Detachment complications, Retinal Detachment drug therapy, Retinal Diseases complications, Retinal Diseases drug therapy, Retrospective Studies, Serum, Visual Acuity, Choroid Diseases diagnosis, Pigment Epithelium of Eye pathology, Retinal Detachment diagnosis, Retinal Diseases diagnosis
Abstract

Purpose: To determine the visual outcome of retinal pigment epithelial detachment (PED) associated with central serous chorioretinopathy (CSC), to further characterize the natural history of these lesions, and to provide a review of previous reports., Participants: Data for 340 consecutive patients with a diagnosis of CSC from January 2001 through December 2004 were retrospectively reviewed. Patients with CSC combined with angiographic evidence of PED were included in the study., Main Outcome Measures: Age, sex, use of corticosteroid medications, presenting visual acuity, and final visual acuity were recorded. Lesion characteristics including location, number of lesions, and laterality were recorded. Clinical outcome measures included resolution or persistence of the PED, progression to retinal pigmentary atrophy, or development of choroidal neovascularization. Fluorescein angiograms were obtained if available., Results: Thirty-four (9%) of 319 patients with angiographic evidence of CSC were diagnosed with PED over a mean follow-up of 49 months (range, 12-165 months; median, 36 months). Mean age of the patients was 47 years (range, 32-69 years; median, 48 years), most of whom were males (68%). Mean initial visual acuity was 20/32 (range, 20/13 to 20/400; median, 20/30). PEDs were commonly unilateral (88%), unifocal (76%), and extrafoveal (82%). Overall mean final visual acuity was 20/25 (range, 20/13 to 20/250; median, 20/25) for all patients. Mean visual acuity for the group of patients with subfoveal PED (18%) was 20/50 (range, 20/25 to 20/250; median, 20/50). Complete resolution of the PED occurred in 65% of patients, with resultant mean visual acuity of 20/25 (range, 20/13 to 20/250; median, 20/25). In this group, localized retinal pigment epithelial atrophy developed in 86%, with mean final visual acuity of 20/25 (range, 20/13 to 20/250; median, 20/25). Persistent PED was observed in 35% of patients, resulting in mean visual acuity of 20/25. There were no cases of choroidal neovascularization., Conclusions: CSC with associated retinal PED may be seen and generally has a good visual prognosis. The most frequent outcome is resolution with retinal pigment epithelial atrophy. Subfoveal PED occurs less commonly and may have a poorer visual prognosis.

Published
2007
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3. The natural history of pigment epithelial detachment associated with central serous chorioretinopathy

Author

Everett Ai, Jumper Jm, Arthur D. Fu, McDonald Hr, Robert N. Johnson, Goff Mj, and Mudvari Ss

Subjects
Adult, Male, Serum, medicine.medical_specialty, Visual acuity, Visual Acuity, Lesion, chemistry.chemical_compound, Retinal Diseases, Ophthalmology, medicine, Humans, Fluorescein Angiography, Pigment Epithelium of Eye, Glucocorticoids, Aged, Retrospective Studies, medicine.diagnostic_test, business.industry, Retinal Detachment, Retinal, Retrospective cohort study, General Medicine, Choroid Diseases, Exudates and Transudates, Middle Aged, Fluorescein angiography, Serous fluid, Choroidal neovascularization, chemistry, Retinal pigment epithelial atrophy, Female, medicine.symptom, business
Abstract

Purpose To determine the visual outcome of retinal pigment epithelial detachment (PED) associated with central serous chorioretinopathy (CSC), to further characterize the natural history of these lesions, and to provide a review of previous reports. Participants Data for 340 consecutive patients with a diagnosis of CSC from January 2001 through December 2004 were retrospectively reviewed. Patients with CSC combined with angiographic evidence of PED were included in the study. Main outcome measures Age, sex, use of corticosteroid medications, presenting visual acuity, and final visual acuity were recorded. Lesion characteristics including location, number of lesions, and laterality were recorded. Clinical outcome measures included resolution or persistence of the PED, progression to retinal pigmentary atrophy, or development of choroidal neovascularization. Fluorescein angiograms were obtained if available. Results Thirty-four (9%) of 319 patients with angiographic evidence of CSC were diagnosed with PED over a mean follow-up of 49 months (range, 12-165 months; median, 36 months). Mean age of the patients was 47 years (range, 32-69 years; median, 48 years), most of whom were males (68%). Mean initial visual acuity was 20/32 (range, 20/13 to 20/400; median, 20/30). PEDs were commonly unilateral (88%), unifocal (76%), and extrafoveal (82%). Overall mean final visual acuity was 20/25 (range, 20/13 to 20/250; median, 20/25) for all patients. Mean visual acuity for the group of patients with subfoveal PED (18%) was 20/50 (range, 20/25 to 20/250; median, 20/50). Complete resolution of the PED occurred in 65% of patients, with resultant mean visual acuity of 20/25 (range, 20/13 to 20/250; median, 20/25). In this group, localized retinal pigment epithelial atrophy developed in 86%, with mean final visual acuity of 20/25 (range, 20/13 to 20/250; median, 20/25). Persistent PED was observed in 35% of patients, resulting in mean visual acuity of 20/25. There were no cases of choroidal neovascularization. Conclusions CSC with associated retinal PED may be seen and generally has a good visual prognosis. The most frequent outcome is resolution with retinal pigment epithelial atrophy. Subfoveal PED occurs less commonly and may have a poorer visual prognosis.

Published
2007

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