Search

Background Several measures of occupational exposure to pesticides have been used to study associations between exposure to pesticides and neurobehavioral outcomes. This study assessed the impact of different exposure measures for glyphosate and mancozeb on the association with neurobehavioral outcomes based on original and recalled self-reported data with 246 smallholder farmers in Uganda. Methods The association between the 6 exposure measures and 6 selected neurobehavioral test scores was investigated using linear multivariable regression models. Exposure measures included original exposure measures for the previous year in 2017: (i) application status (yes/no), (ii) number of application days, (iii) average exposure-intensity scores (EIS) of an application and (iv) number of EIS-weighted application days. Two additional measures were collected in 2019: (v) recalled application status and (vi) recalled EIS for the respective periods in 2017. Results Recalled applicator status and EIS were between 1.2 and 1.4 times more frequent and higher for both pesticides than the original application status and EIS. Adverse associations between the different original measures of exposure to glyphosate and 4 neurobehavioral tests were observed. Glyphosate exposure based on recalled information and all mancozeb exposure measures were not associated with the neurobehavioral outcomes. Conclusions The relation between the different original self-reported glyphosate exposure measures and neurobehavioral test scores appeared to be robust. When based on recalled exposure measures, associations observed with the original exposure measures were no longer present. Therefore, future epidemiological studies on self-reported exposure should critically evaluate the potential bias towards the null in observed exposure–response associations. [ABSTRACT FROM AUTHOR]

Objectives: Natural language processing (NLP) represents one of the adjunct technologies within artificial intelligence and machine learning, creating structure out of unstructured data. This study aims to assess the performance of employing NLP to identify and categorize unstructured data within the emergency medicine (EM) setting. Methods: We systematically searched publications related to EM research and NLP across databases including MEDLINE, Embase, Scopus, CENTRAL, and ProQuest Dissertations & Theses Global. Independent reviewers screened, reviewed, and evaluated article quality and bias. NLP usage was categorized into syndromic surveillance, radiologic interpretation, and identification of specific diseases/events/syndromes, with respective sensitivity analysis reported. Performance metrics for NLP usage were calculated and the overall area under the summary of receiver operating characteristic curve (SROC) was determined. Results: A total of 27 studies underwent meta‐analysis. Findings indicated an overall mean sensitivity (recall) of 82%–87%, specificity of 95%, with the area under the SROC at 0.96 (95% CI 0.94–0.98). Optimal performance using NLP was observed in radiologic interpretation, demonstrating an overall mean sensitivity of 93% and specificity of 96%. Conclusions: Our analysis revealed a generally favorable performance accuracy in using NLP within EM research, particularly in the realm of radiologic interpretation. Consequently, we advocate for the adoption of NLP‐based research to augment EM health care management. [ABSTRACT FROM AUTHOR]

Background: Artificial intelligence (AI) offers a promising solution to expedite various phases of the systematic review process such as screening. Objective: We aimed to assess the accuracy of an AI tool in identifying eligible references for a systematic review compared to identification by human assessors. Methods: For the case study (a systematic review of knowledge translation interventions), we used a diagnostic accuracy design and independently assessed for eligibility a set of articles (n = 300) using human raters and the AI system DistillerAI (Evidence Partners, Ottawa, Canada). We analysed a series of 64 possible confidence levels for the AI's decisions and calculated several standard parameters of diagnostic accuracy for each. Results: When set to a lower AI confidence threshold of 0.1 or greater and an upper threshold of 0.9 or lower, DistillerAI made article selection decisions very similarly to human assessors. Within this range, DistillerAI made a decision on the majority of articles (93–100%), with a sensitivity of 1.0 and specificity ranging from 0.9 to 1.0. Conclusion: DistillerAI appears to be accurate in its assessment of articles in a case study of 300 articles. Further experimentation with DistillerAI will establish its performance among other subject areas. [ABSTRACT FROM AUTHOR]

Background: Antidepressants have been proposed to act via their influence on emotional processing. We investigated the effect of discontinuing maintenance antidepressant treatment on positive and negative self-referential recall and the association between self-referential recall and risk of relapse. Methods: The ANTLER trial was a large (N = 478) pragmatic double-blind trial investigating the clinical effectiveness of long-term antidepressant treatment for preventing relapse in primary care patients. Participants were randomised to continue their maintenance antidepressants or discontinue via a taper to placebo. We analysed memory for positive and negative personality descriptors, assessed at baseline, 12- and 52-week follow-up. Results: The recall task was completed by 437 participants. There was no evidence of an effect of discontinuation on self-referential recall at 12 [positive recall ratio 1.00, 95% CI (0.90–1.11), p = 0.93; negative recall ratio 1.00 (0.87–1.14), p = 0.87] or 52 weeks [positive recall ratio 1.03 (0.91–1.17), p = 0.62; negative recall ratio 1.00 (0.86–1.15), p = 0.96; ratios larger than one indicate higher recall in the discontinuation group], and no evidence of an association between recall at baseline or 12 weeks and later relapse [baseline, positive hazard ratio (HR) 1.02 (0.93–1.12), p = 0.74; negative HR 1.01 (0.90–1.13), p = 0.87; 12 weeks, positive HR 0.99 (0.89–1.09), p = 0.81; negative HR 0.98 (0.84–1.14), p = 0.78; ratios larger than one indicate a higher frequency of relapse in those with higher recall]. Conclusions: We found no evidence that discontinuing long-term antidepressants altered self-referential recall or that self-referential recall was associated with risk of relapse. These findings suggest that self-referential recall is not a neuropsychological marker of antidepressant action. [ABSTRACT FROM AUTHOR]

Constructive episodic retrieval processes play an adaptive role in supporting divergent thinking (i.e., creatively combining diverse bits of information) and means-end problem solving (i.e., generating steps to solve a social problem). However, the constructive nature of episodic memory that supports these adaptive functions also leads to memory error. In three experiments we aimed to identify a direct link between divergent thinking and means-end problem solving – as assessed in the Alternative Uses Task (AUT) and Means-End Problem Solving (MEPS) task – with the generation of false memories in the Deese-Roediger-McDermott paradigm. In Experiment 1, we replicated prior findings where false memory was positively correlated with performance on the AUT, and also showed for the first time that increased performance in the MEPS task is associated with increased false recall. In Experiment 2, we demonstrated that the link between false recall and performance on the MEPS task did not extend to other forms of problem solving, as assessed with the Everyday Descriptions Task (EDT). In Experiment 3, we showed that when the EDT was preceded by the MEPS task in an attempt to influence participants to engage in a similar episodic-problem solving strategy, performance in both tasks was correlated with false memory. These findings provide evidence for a direct link between the adaptive benefits of constructive episodic processes, in the form of enhanced divergent creative thinking and problem solving, and costs, in the form of increased memory error. [ABSTRACT FROM AUTHOR]

The production effect refers to the finding that words read aloud are better remembered than those read silently. This pattern has most often been explained as arising from the incorporation of sensorimotor elements into the item representation at study, which could then be used to guide performance at later test. This theoretical framework views aloud items as being distinctive in relation to silent items, and thus the effect was thought to emerge only when production was manipulated within-subjects. This claim was later challenged, and a reliable (albeit smaller) between-subject production effect has since been shown in recognition memory. Across a series of meta-analyses, we extend this earlier work, replicating the between-subject production effect for recognition, and demonstrating no such effect for overall target recall. However, supporting recent theoretical claims, we further observed an interaction between the production effect and serial position within recall, such that a production effect was observed for late time points but not early time points (a similar, albeit smaller and noncredible trend was observed for recognition). Finally, we provide evidence that production reduces off-list intrusions. In summary, production has a reliable impact on recognition memory when manipulated between-subjects, but a more complex relationship with recall performance. [ABSTRACT FROM AUTHOR]

Familiar music facilitates memory retrieval in adults with dementia. However, mechanisms behind this effect, and its generality, are unclear because of a lack of parallel work in healthy aging. Exposure to familiar music enhances spontaneous recall of memories directly cued by the music, but it is unknown whether such effects extend to deliberate recall more generally – e.g., to memories not directly linked to the music being played. It is also unclear whether familiar music boosts recall of specific episodes versus more generalised semantic memories, or whether effects are driven by domain-general mechanisms (e.g., improved mood). In a registered report study, we examined effects of familiar music on deliberate recall in healthy adults ages 65–80 years (N = 75) by presenting familiar music from earlier in life, unfamiliar music, and non-musical audio clips across three sessions. After each clip, we assessed free recall of remote memories for pre-selected events. Contrary to our hypotheses, we found no effects of music exposure on recall of prompted events, though familiar music evoked spontaneous memories most often. These results suggest that effects of familiar music on recall may be limited to memories specifically evoked in response to the music (Preprint and registered report protocol at ). [ABSTRACT FROM AUTHOR]

The forward testing effect (FTE) refers to the finding that retrieval practice of previously studied material can facilitate recall of newly studied (critical) material. Such interim retrieval practice can also lead to a differential FTE, i.e., a more pronounced FTE for items at early than later serial positions in the critical material. The present study examined whether this differential FTE also holds with interim semantic generation of extra-list items, and whether it is influenced by study material. Consistent with prior work, the results of two experiments showed that both interim retrieval practice and interim semantic generation induce the general (list-level) FTE when unrelated study lists are applied, whereas retrieval practice only creates the effect with categorised study lists. Critically, however, the differential FTE was present in response to retrieval practice but absent in response to semantic generation. This pattern held regardless of which material was studied, thus experimentally dissociating the general (list-level) from the differential (item-level) FTE. The findings may suggest that retrieval practice, but not semantic generation, induces a reset of the encoding process which promotes attentional encoding such that a more pronounced FTE arises for early than middle and late serial positions in the critical list. [ABSTRACT FROM AUTHOR]

Recurrent fluctuations in health states can occur as a result of long-term conditions with episodic symptoms or through side effects of cycles of treatment. Fluctuations and associated duration of symptoms can be predictable (eg, side effects of chemotherapy treatment) or unpredictable (eg, relapse in multiple sclerosis). Such recurrent fluctuations in health states can have an important impact on a person's health-related quality of life. When symptoms vary by time of day, day of the week, or during the month, it is challenging to obtain reliable health-related quality of life estimates for use in assessing cost-effectiveness of interventions. The adequacy of the quality of life estimate will be affected by (1) the standard recall period associated with the chosen measure (eg, "health today" EQ-5D, "past 4 weeks" for SF-36/SF-6D) and the way that respondents understand and make judgments about these recall periods, (2) the chosen time points for assessing health-related quality of life in relation to the fluctuations in health, and (3) the assumptions used to interpolate between measurement time points and thus calculate the quality-adjusted life-years. These issues have not received sufficient methodological attention and instead remain poorly accounted for in economic analyses. There is potential for these issues to considerably distort treatment decisions away from the optimal allocation. This article brings together evidence from health economics, psychology, and behavioral economics to explore these challenges in depth; presents the solutions that have been applied to date; and details a methodological research agenda for measuring quality-adjusted life-years in recurrent fluctuating health states. [ABSTRACT FROM AUTHOR]

Background: There are few publications on search strategies to identify diagnostic test accuracy (DTA) studies in lilacs. Objective: To translate and customise medline search strategies for use in lilacs and assess their retrieval of studies in Cochrane DTA systematic reviews. Method: We developed a six‐step process to translate and customise medline search strategies for use in lilacs (iAHx interface). We identified medline search strategies of published Cochrane DTA reviews, translated/customised them for use in lilacs, ran searches in lilacs and compared the retrieval results of our translated search strategy versus the one used in the published reviews. Results: Our lilacs search strategies translated/customised from the medline strategies retrieved studies in 70 Cochrane DTA reviews. Only 29 of these reviews stated that they had searched the lilacs database and 21 published their lilacs search strategies. Few had used the lilacs database search tools, none exploded the subject headings, and 86% used only English terms. Conclusion: Translating and tailoring a medline search strategy for the lilacs database resulted in the retrieval of DTA studies that would have been missed otherwise. [ABSTRACT FROM AUTHOR]

Background: Searching for topics within large biomedical databases can be challenging, especially when topics are complex, diffuse, emerging or lack definitional clarity. Experimentally derived topic search filters offer a reliable solution to effective retrieval; however, their number and range of subject foci remain unknown. Objectives: This systematic scoping review aims to identify and describe available experimentally developed topic search filters. Methods: Reports on topic search filter development (1990‐) were sought using grey literature sources and 15 databases. Reports describing the conception and prospective development of a database‐specific topic search and including an objectively measured estimate of its performance ('sensitivity') were included. Results: Fifty‐four reports met inclusion criteria. Data were extracted and thematically synthesised to describe the characteristics of 58 topic search filters. Discussion: Topic search filters are proliferating and cover a wide range of subjects. Filter reports, however, often lack clear definitions of concepts and topic scope to guide users. Without standardised terminology, filters are challenging to find. Information specialists may benefit from a centralised topic filter repository and appraisal checklists to facilitate quality assessment. Conclusion: Findings will help information specialists identify existing topic search filters and assist filter developers to build on current knowledge in the field. [ABSTRACT FROM AUTHOR]

Background: Evidence synthesis reviews in health care rely on the efficient identification of research evidence, particularly evidence from randomised controlled trials (RCTs). There are no recently validated filters to identify RCTs in the Cumulative Index to Nursing and Allied Health Literature (CINAHL Plus). Objectives: To develop, test and validate a search filter to identify reports of RCTs from CINAHL Plus. Methods: Nine sets of relevant and irrelevant records were identified to develop and test search filters iteratively. Two sets were used to validate the sensitivity and precision of the filters. The performance of two previously published filters and the filter built into EBSCOhost was evaluated. Results: We present a validated filter which offers sensitivity of 0.88 (95% CI: 0.77–0.95) and precision of 0.36 (95% CI: 0.31–0.41). This is comparable to the sensitivity of published filters, but has much better precision. Conclusions: A sensitive and precise filter, developed using records selected based on title and abstract information, is available for identifying reports of RCTs in the CINAHL Plus database via EBSCOhost. Using this filter is likely to reduce the number of results needing to be screened to a quarter of those retrieved by other published filters. [ABSTRACT FROM AUTHOR]

In health economics, the use of patient recall of health care utilisation information is common, including in national health surveys. However, the types and magnitude of measurement error that relate to different recall periods are not well understood. This study assessed the accuracy of recalled doctor visits over 2-week, 3-month, and 12-month periods by comparing self-report with routine administrative Australian Medicare data. Approximately 5,000 patients enrolled in an Australian study were pseudo-randomised using birth dates to report visits to a doctor over three separate recall periods. When comparing patient recall with visits recorded in administrative information from Medicare Australia, both bias and variance were minimised for the 12-month recall period. This may reflect telescoping that occurs with shorter recall periods (participants pulling in important events that fall outside the period). Using shorter recall periods scaled to represent longer periods is likely to bias results. There were associations between recall error and patient characteristics. The impact of recall error is demonstrated with a cost-effectiveness analysis using costs of doctor visits and a regression example predicting number of doctor visits. The findings have important implications for surveying health service utilisation for use in economic evaluation, econometric analyses, and routine national health surveys. [ABSTRACT FROM AUTHOR]

Purpose: To investigate the relationship between retrospectively and contemporaneously collected patient-reported outcome measures (PROMs) and the influence on this relationship of patients' age and socio-economic status and the length of time.Methods: Patients undergoing hip or knee replacement in four hospitals who had completed a pre-operative questionnaire were invited to recall their pre-operative health status shortly after surgery. The questionnaires included a disease-specific (Oxford Hip Score; Oxford Knee Score) and generic (EQ-5D-3L) PROM. Consistency and absolute agreement between contemporary and retrospective reports were investigated using intraclass correlations (ICCs). Differences were visualised using Bland-Altman plots. Linear regression analysis explored whether retrospective can predict contemporary PROMs.Results: Patients' recalled health statuses were similar to their contemporaneous reports, with no significant systematic bias. Absolute agreement for disease-specific PROMs was very strong (ICC 0.82) and stronger than for the generic PROM (ICC 0.60, 0.62). Agreement was consistently strong across the range of severity of a patient's condition, age and socio-economic status. Patients' age and socio-economic status had no significant influence on size of difference and direction of recall, although reliability of recall was slightly worse among the over-75s versus under-60s for hips (Oxford Hip Score ICC 0.88 vs. 0.78). Mean retrospective PROMs for groups or populations of patients can reliably predict what mean contemporary reports of PROMs would have been.Conclusion: Retrospective PROMs can be used to obtain a baseline assessment of health status when contemporary collection is not feasible or cost effective. Research is needed to determine the feasibility of retrospective PROMs in emergency admissions. [ABSTRACT FROM AUTHOR]

Objective: Binge eating disorder (BED), characterized by recurrent episodes of loss of control overeating, is highly comorbid with overweight and obesity. Both loss of control eating and higher body mass index have been associated with poor memory. The current study sought to clarify the relationships between BED, weight and memory. Specifically, visual memory was examined, given evidence of impaired visuospatial abilities in overweight individuals and little research on visual memory in BED.Method: Overweight and normal-weight women with BED and matched healthy controls were administered the Rey Complex Figure Test.Results: Planned contrasts revealed that normal-weight healthy controls performed better than all other groups on the immediate and delayed recall portions of the task. Performance on the immediate recall portion was better among normal-weight individuals than overweight individuals, and performance on both the immediate and delayed recall portions was better among individuals without BED than those with BED. No differences between groups were seen on the copy or recognition trials.Conclusions: Visual memory appears to be impaired among overweight participants and both normal and overweight participants with BED. This finding was specific to retrieval. Replication of this finding in BED using different measures of memory is needed. [ABSTRACT FROM AUTHOR]

Context Patient recall of treatment information is a key variable towards chronic disease ( CD) management. It is unclear what communication and patient participation characteristics predict recall. Objectives To assess what aspects of doctor-patient communication predict patient recall of medication information. To describe lifestyle treatment recall, in CD primary care patients. Design Observational study within a RCT. Setting & participants Community-based primary care ( PC) practices. Family physicians (n=18): practicing >5 years, with a CD patient caseload. Patients (n=159): >40 years old, English speaking, computer literate, off-target hypertension, type II diabetes and/or dyslipidaemia. Main variables Patient characteristics: age, education, number of CDs. Information characteristics: length of encounter, medication status, medication class. Communication variables: socio-emotional utterances, physician dominance and communication control scores and PACE (ask, check and express) utterances, measured by RIAS. Number of medication themes, dialogue and initiative measured by MEDICODE. Main outcome measures Recall of CD, lifestyle treatment and medication information. Results Frequency of lifestyle discussions varied by topic. Patients recalled 43% (alcohol), 52% (diet) to 70% (exercise) of discussions. Two and a half of six possible medication themes were broached per medication discussion. Less than one was recalled. Discussing more themes, greater dialogue and patient initiative were significant predictors of improved medication information recall. Discussion Critical treatment information is infrequently exchanged. Active patient engagement and explicit conversations about medications are associated with improved treatment information recall in off-target CD patients followed in PC. Conclusion Providers cannot take for granted that long-term off-target CD patients recall information. They need to encourage patient participation to improve recall of treatment information. [ABSTRACT FROM AUTHOR]

Purpose: Ambulatory and diary methods of self-reported symptoms and well-being have received increasing interest in recent years. These methods are a valuable addition to traditional strategies for the assessment of patient-reported outcomes (PROs) in that they capture patients' recent symptom experiences repeatedly in their natural environments. In this article, we review ways that incorporating diary methods into PRO measurement can facilitate research on quality of life.Methods: Several diary methods are currently available, and they include "real-time" (Ecological Momentary Assessment) and "near-real-time" (end-of-day assessments, Day Reconstruction Method) formats. We identify the key benefits of these methods for PRO research.Results: (1) In validity testing, diary assessments can serve as a standard for evaluating the ecological validity and for identifying recall biases of PRO instruments with longer-term recall formats. (2) In research and clinical settings, diaries have the ability to closely capture variations and dynamic changes in quality of life that are difficult or not possible to obtain from traditional PRO assessments. (3) In test construction, repeated diary assessments can expand understanding of the measurement characteristics (e.g., reliability, dimensionality) of PROs in that parameters for differences between people can be compared with those for variation within people.Conclusions: Diary assessment strategies can enrich the repertoire of PRO assessment tools and enhance the measurement of patients' quality of life. [ABSTRACT FROM AUTHOR]

Although it is well known that organized lists of words (e.g., categories) are recalled better than unrelated lists, little research has examined whether participants can predict how categorical relatedness influences recall. In two experiments, participants studied lists of words that included items from big categories (12 items), small categories (4 items), and unrelated items, and provided immediate JOLs. In Experiment 1, free recall was highest for items from large categories and lowest for unrelated items. Importantly, participants were sensitive to the effects of category size on recall, with JOLs to items from big categories actually increasing over the study list. In Experiment 2, one group of participants was cued to recall all exemplars from the categories in a blocked manner, whereas the other group was cued in a random order. As expected, the random group did not show the recall benefit for big categories over small categories observed in free recall, while the blocked group did. Critically, the pattern of metacognitive judgments closely matched actual cued recall performance. Participants' JOLs were sensitive to the interaction between category size and output order, demonstrating a relatively sophisticated strategy that incorporates the interaction of multiple extrinsic cues in predicting recall. [ABSTRACT FROM AUTHOR]

Repeated words are often reduced in prosodic prominence, but the underlying mechanisms remain unclear. The present study contrasted two theories: does prosodic reduction reflect the choice of a particular linguistic form, or does ease of retrieval within the language production system lead to facilitated, less prominent productions? One test of facilitation-based theories is suggested by findings on human memory: whether a second presentation of an item benefits later memory is predicted by the item's availability at the time of the second presentation. If prosodic reduction partially reflects facilitated retrieval, it should predict later memory. One naive participant described to another participant routes on a map. Critical items were mentioned twice. Following the map task, the speaker attempted written recall of the mentioned items. As expected, acoustic intensity of the second mentions predicted later recall in the same way that difficulty of retrieval has in other tasks. This pattern suggests that one source of prosodic reduction is facilitation within the language production system. [ABSTRACT FROM AUTHOR]

Three experiments investigated whether and how the learning of spelling by French university students is influenced by the graphotactic legitimacy of the spellings. Participants were exposed to three types of novel spellings: AB, which do not contain doublets (e.g., guprane); AAB, with a doublet before a single consonant, which is legitimate in French (e.g., gupprane); and ABB, with a doublet after a single consonant, which is illegitimate (e.g., guprrane). In Experiment 1, the nonwords were embedded within texts that participants read for meaning. In Experiment 2, participants read the nonwords in isolation, with or without instruction to memorize their spellings; they copied the nonwords in Experiment 3. In all of these conditions, AB and AAB spellings were learned more readily than ABB spellings. Although participants were highly knowledgeable about the illegitimacy of ABB spellings, the orthographic distinctiveness of these spellings did not make them easier to recall than legitimate spellings. When recalling ABB spellings, participants sometimes made transposition errors, doubling the wrong consonant of a cluster (e.g., spelling gupprane instead of guprrane). Participants almost never transposed the doubling for AAB items. Transposition errors, biased in the direction of replacing illegitimate with legitimate orthographic patterns, show that graphotactic knowledge influences memory for specific items. An analysis of the spellings produced in the copy phase and final recall test of Experiment 3 further suggests that transposition errors resulted not so much from reconstructive processes at the time of recall but from reconstructive processes or inefficient encoding at earlier points. [ABSTRACT FROM AUTHOR]

The article discusses a study conducted to examine whether substitution of benzodiazepine sedatives with dexmedetomidine in intensive care unit (ICU) influences patient recall and acute stress disorder. The study found that the median duration of mechanical ventilation was 3.4 days in dexmedetomidine patients whereas 2.9 days in midazolam patients. The study reveals that five midazolam patients developed the condition of delirium whereas hypotension occurred in 10 dexmedotomidine patients.

We present a holographic theory of human memory. According to the theory, a subject's vocabulary resides in a dynamic distributed representation—a hologram. Studying or recalling a word alters both the existing representation of that word in the hologram and all words associated with it. Recall is always prompted by a recall cue (either a start instruction or the word just recalled). Order of report is a joint function of the item and associative information residing in the hologram at the time the report is made. We apply the model to archival data involving simple free recall, learning in multitrial free recall, simple serial recall, and learning in multitrial serial recall. The model captures accuracy and order of report in both free and serial recall. It also captures learning and subjective organisation in multitrial free recall. We offer the model as an alternative to the short- and long-term account of memory postulated in the modal model. [ABSTRACT FROM AUTHOR]

Three experiments investigated the mnemonic effects of source-constrained retrieval in the survival-processing paradigm. Participants were asked to make survival-based or control decisions (pleasantness or moving judgments) about items prior to a source identification test. The source test was followed by a surprise free recall test for all items processed during the experiment, including the new items (foils) presented during the source test. For the source test itself, when asked about the content of prior processing-did you make a survival or a pleasantness decision about this item?-no differences were found between the survival and control conditions. The final free recall data revealed a different pattern: When participants were asked to decide whether an item had been processed previously for survival, that item was subsequently recalled better than when the source query asked about pleasantness or relevance to a moving scenario. This mnemonic boost occurred across-the-board-for items processed during the initial rating phase and for the new items. These data extend the generality of source-constrained retrieval effects and have implications for understanding the proximate mechanisms that underlie the oft-replicated survival-processing advantage in recall and recognition. [ABSTRACT FROM AUTHOR]

Background Late diagnosis is a considered to be a major factor contributing to poorer cancer survival rates in the UK. Interventions have focussed on the promotion of earlier diagnosis in patients with potential cancer symptoms. However, to assess the effectiveness of these interventions, the time from symptom onset to presentation needs to be reliably and accurately measured. This qualitative study explored the use of calendar landmarking instruments in cancer symptom research. Methods We performed a secondary analysis of transcripts of interviews using the calendar landmarking instrument, undertaken with patients who had either been diagnosed with cancer (n = 40, IRCO study, Western Australia), or who had symptoms suggestive of cancer (n = 38, SYMPTOM study, North East and Eastern England). We used constant comparison methods to identify use of the calendar landmarking instruments and the impact of their application. Results The calendar landmarking instrument appeared to help many patients, either by acting as a prompt or helping to refine recall of events. A combination of personal (e.g. birthday) and national (e.g. Christmas) landmarks seemed to be the most effective. Calendar landmarking instruments appeared more useful where the time period between onset of symptoms and date of first consultation was less than three months. The interviewee's age, gender and cancer type did not appear to influence whether or not the instrument facilitated recall, and there were no instances where the use of the instrument resulted in the disclosure of a new first symptom. Symptoms of similar chronic conditions could create difficulties when applying the instrument; it was difficult for these participants to characterise and disentangle their symptoms which prompted their decisions to seek help. Some participants tended to prefer to use their own, already personalised, diaries to assist in their recall of events. Conclusions This study is the first to describe the potential role of calendar landmarking instruments to support research interviews which explore symptoms and events along the cancer diagnostic pathway. The major challenge remains as to whether they actually improve accuracy of recall. [ABSTRACT FROM AUTHOR]

The present research assessed the potential effects of expecting to teach on learning. In two experiments, participants studied passages either in preparation for a later test or in preparation for teaching the passage to another student who would then be tested. In reality, all participants were tested, and no one actually engaged in teaching. Participants expecting to teach produced more complete and better organized free recall of the passage (Experiment 1) and, in general, correctly answered more questions about the passage than did participants expecting a test (Experiment 1), particularly questions covering main points (Experiment 2), consistent with their having engaged in more effective learning strategies. Instilling an expectation to teach thus seems to be a simple, inexpensive intervention with the potential to increase learning efficiency at home and in the classroom. [ABSTRACT FROM AUTHOR]

Background Life course influences, including country of residence and country of birth, are associated with frailty index scores. We investigated these associations using performance-based health measures. Methods Among 33,745 participants age 50+ (mean age 64.8 ± 10.1; 55% women) in the Survey of Health, Ageing, and Retirement in Europe, grip strength, delayed word recall, and semantic verbal fluency were assessed. Participants were grouped by country of residence (Northern/Western Europe or Southern/ Eastern Europe), and by country of birth (native-born, immigrants born in low- and middle-income countries [LMICs], or immigrants born in high-income countries [HICs]). Results Participants in Southern/Eastern Europe had lower mean test scores than those in Northern/Western Europe, and their scores did not differ by country of birth group. In Northern/ Western Europe, compared with native-born participants, LMIC-born immigrants demonstrated lower mean grip strength (32.8 ± 7.6 kg vs. 35.7 ± 7.7 kg), delayed recall (2.9 ± 1.9 vs. 3.6 ± 1.9), and verbal fluency scores (16.0 ± 6.9 vs. 20.3 ± 7.0). HIC-born immigrants had mean scores higher than LMIC-born immigrants, but lower than native-born participants (all p<.001). Conclusions Cognitive and motor performance, measured from late middle age, were associated with national income levels of both country of residence and country of birth. This was similar to previously observed differences in frailty index scores. [ABSTRACT FROM AUTHOR]

Recall of recently heard words is affected by the clarity of presentation: Even if all words are presented with sufficient clarity for successful recognition, those that are more difficult to hear are less likely to be recalled. Such a result demonstrates that memory processing depends on more than whether a word is simply 'recognized' versus 'not recognized.' More surprising is that, when a single item in a list of spoken words is acoustically masked, prior words that were heard with full clarity are also less likely to be recalled. To account for such a phenomenon, we developed the linking-by-active-maintenance model (LAMM). This computational model of perception and encoding predicts that these effects will be time dependent. Here we challenged our model by investigating whether and how the impact of acoustic masking on memory depends on presentation rate. We found that a slower presentation rate causes a more disruptive impact of stimulus degradation on prior, clearly heard words than does a fast rate. These results are unexpected according to prior theories of effortful listening, but we demonstrated that they can be accounted for by LAMM. [ABSTRACT FROM AUTHOR]

In five experiments, we extended the production effect-better memory for items said aloud than for items read silently-to paired-associate learning, the goal being to explore whether production enhances associative information in addition to enhancing item information. In Experiments 1 and 2, we used a semantic-relatedness task in addition to the production manipulation and found no evidence of a production effect, whether the measure was cued recall or item recognition. Experiment 3 showed that the semantic-relatedness task had overshadowed the production effect; the effect was present when the semantic-relatedness task was removed, again whether cued recall or item recognition was the measure. Experiments 4 and 5 provided further evidence that production can enhance recall for word pairs and, using an associate recognition test with intact versus rearranged pairs, indicated that production may also enhance associative information. That production boosts memory for both types of information is considered in terms of distinctive encoding. [ABSTRACT FROM AUTHOR]

Objective The aim of this study was to compare the performance of three search methods in the retrieval of relevant clinical trials from PubMed to answer specific clinical questions. Methods Included studies of a sample of 100 Cochrane reviews which recorded in PubMed were considered as the reference standard. The search queries were formulated based on the systematic review titles. Precision, recall and number of retrieved records for limiting the results to clinical trial publication type, and using sensitive and specific clinical queries filters were compared. The number of keywords, presence of specific names of intervention and syndrome in the search keywords were used in a model to predict the recalls and precisions. Results The Clinical queries-sensitive search strategy retrieved the largest number of records (33) and had the highest recall (41.6%) and lowest precision (4.8%). The presence of specific intervention name was the only significant predictor of all recalls and precisions ( P = 0.016). Conclusion The recall and precision of combination of simple clinical search queries and methodological search filters to find clinical trials in various subjects were considerably low. The limit field strategy yielded in higher precision and fewer retrieved records and approximately similar recall, compared with the clinical queries-sensitive strategy. Presence of specific intervention name in the search keywords increased both recall and precision. [ABSTRACT FROM AUTHOR]

There are relatively few studies on learning and delayed memory with attention-deficit/hyperactivity disorder (ADHD). The objective of the present study was to examine acquisition, free delayed memory, and recognition skills in medication naive children and adolescents aged 8–16 years with ADHD combined subtype (36 participants) and inattentive subtype (45) compared to 50 healthy controls (HC) aged 8–17 years. Learning and delayed memory were assessed with the Hopkins Verbal Learning Test–Revised and the Brief Visuospatial Memory Test–Revised, which have compatible methods of administration, test format, and score ranges. The results showed that children with both ADHD subtypes scored significantly below HC in acquisition, free delayed memory, and recognition, even when controlling for the effect of IQ. Comparing phases in the learning process showed an initial deficit in acquisition but no increase in effect size in subsequent testing of free delayed memory or recognition. The study indicates that learning and delayed memory processes are impaired in both combined and inattentive subtypes of ADHD and that the deficits are not merely an artifact of IQ. The study indicates that emphasis must be put on the acquisition phase and how students with ADHD organize and encode new information. [ABSTRACT FROM PUBLISHER]

Two experiments are reported in which we used type-2 signal detection theory to separate the effects of semantic categorization on early- and late-selection processes in free and cued recall. In Experiment 1, participants studied cue-target pairs for which the targets belonged to two, six, or 24 semantic categories, and later the participants were required to recall the targets either with (cued recall) or without (free recall) the studied cues. A confidence rating and a report decision were also required, so that we could compute both forced-report quantity and metacognitive resolution (type-2 discrimination), which served as our estimates of early- and late-selection processes, respectively. Consistent with prior research, having fewer categories enhanced the early-selection process (in performance, two > six > 24 categories). However, in contrast, the late-selection process was impaired (24 > six = two categories). In Experiment 2, encoding of paired associates, for which the targets belonged to either two or 20 semantic categories, was manipulated by having participants either form interactive images or engage in rote repetition. Having fewer categories again was associated with enhanced early selection (two > 20 categories); this effect was greater for rote repetition than for interactive imagery, and greater for free recall than for cued recall. However, late selection again showed the opposite pattern (20 > two categories), even with interactive-imagery encoding, which formed distinctive, individuated memory traces. The results are discussed in terms of early- and late-selection processes in retrieval, as well as overt versus covert recognition. [ABSTRACT FROM AUTHOR]

This study investigated how different doses of alcohol affected eyewitness recall. Participants ( N = 126) were randomly assigned to three groups with different blood alcohol concentration ( BAC), either a control group (mean BAC 0.00%, N = 42), a lower alcohol dose group (mean BAC 0.04%, N = 40), or a higher alcohol dose group (mean BAC 0.06%, N = 44). After consumption, participants witnessed a movie of a mock crime and were interviewed one week later. The main results showed that witnesses with the higher intoxication level recalled fewer details compared to witnesses with the lower intoxication level. The amount of alcohol consumed did not have an impact on the accuracy rate. No sex differences were found. The results are discussed in the light of past research. We conclude that more studies are needed before recommendations can be made to an applied setting. [ABSTRACT FROM AUTHOR]

The frequency effect in short-term serial recall is influenced by the composition of lists. In pure lists, a robust advantage in the recall of high-frequency (HF) words is observed, yet in alternating mixed lists, HF and low-frequency (LF) words are recalled equally well. It has been argued that the preexisting associations between all list items determine a single, global level of supportive activation that assists item recall. Preexisting associations between items are assumed to be a function of language co-occurrence; HF-HF associations are high, LF-LF associations are low, and mixed associations are intermediate in activation strength. This account, however, is based on results when alternating lists with equal numbers of HF and LF words were used. It is possible that directional association between adjacent list items is responsible for the recall patterns reported. In the present experiment, the recall of three forms of mixed lists-those with equal numbers of HF and LF items and pure lists-was examined to test the extent to which item-to-item associations are present in serial recall. Furthermore, conditional probabilities were used to examine more closely the evidence for a contribution, since correct-in-position scoring may mask recall that is dependent on the recall of prior items. The results suggest that an item-to-item effect is clearly present for early but not late list items, and they implicate an additional factor, perhaps the availability of resources at output, in the recall of late list items. [ABSTRACT FROM AUTHOR]

Retrieving some items from memory can impair the subsequent recall of other related but not retrieved items, a phenomenon called retrieval-induced forgetting (RIF). The dominant explanation of RIF-the inhibition account-asserts that forgetting occurs because related items are suppressed during retrieval practice to reduce retrieval competition. This item inhibition persists, making it more difficult to recall the related items on a later test. In our set of experiments, each category was designed such that each exemplar belonged to one of two subcategories (e.g., each BIRD exemplar was either a bird of prey or a pet bird), but this subcategory information was not made explicit during study or retrieval practice. Practicing retrieval of items from only one subcategory led to RIF for items from the other subcategory when cued only with the overall category label (BIRD) at test. However, adapting the technique of Gardiner, Craik, and Birtwistle (Journal of Learning and Verbal Behavior 11:778-783, ), providing subcategory cues during the final test eliminated RIF. The results challenge the inhibition account's fundamental assumption of cue independence but are consistent with a cue-based interference account. [ABSTRACT FROM AUTHOR]

The customary assumption in the study of human learning using alternating study and test trials is that learning occurs during study trials and that test trials are useful only to measure learning. In fact, tests seem to play little role in the development of learning, because the learning curve is similar even when the number of test trials varies widely (Tulving, Journal of Verbal Learning and Verbal Behavior 6:175-184, ). However, this outcome seems odd, because other research has shown that testing fosters greater long-term learning than does studying. We report three experiments addressing whether tests affect the shape of the learning curve. In two of the experiments, we examined this issue by varying the number of spaced study trials in a sequence and examining performance on only a single test trial at the end of the series (a 'pure-study' learning curve). We compared these pure-study learning curves to standard learning curves and found that the standard curves increase more rapidly and reach a higher level in both free recall (Exp. 1) and paired-associate learning (Exp. 2). In Experiment 3, we provided additional study trials in the 'pure-study' condition to determine whether the standard (study-test) condition would prove superior to a study-study condition. The standard condition still produced better retention on both immediate and delayed tests. Our experiments show that test trials play an important role in the development of learning using both free-recall (Exps. 1 and 3) and paired-associate (Exp. 2) procedures. Theories of learning have emphasized processes that occur during study, but our results show that processes engaged during tests are also critical. [ABSTRACT FROM AUTHOR]

Serial recall is often assumed to involve response suppression: the removal or inhibition of items already recalled so that they are not recalled again. Evidence for response suppression includes repetition inhibition and the separation of erroneous repetitions. Some theorists have suggested that response suppression, by eliminating competing responses, also contributes to recency in forward serial recall. We present experiments in which performance on the final item was examined as a function of whether or not the preceding retrievals entailed suppression of potential response competitors. In line with the predictions of response suppression, recency was found to be reduced when the earlier recall errors consisted of intrusion errors (which leave list items unsuppressed) rather than transposition errors (which involve suppression). [ABSTRACT FROM AUTHOR]

The finding that serial recall performance for visually presented items is impaired by concurrently presented task-irrelevant speech or sounds is referred to as the irrelevant-speech/-sound effect (ISE). Substantial evidence has indicated that the impairment of serial rehearsal can result in an ISE, and this may be explained by several models. The present series of experiments has demonstrated an ISE in surprise nonserial recognition tasks in which participants were unaware of the need to maintain a large number of visual items for a later memory test, suggesting that neither the rehearsal nor maintenance of order information is necessary for observing the ISE. This effect was observed for both steady-state and changing-state irrelevant sounds, suggesting that the present results do not derive from a confusion of order information, but instead provide evidence that identity representations can also be impaired by irrelevant sound. [ABSTRACT FROM AUTHOR]

Although successful retrieval practice is beneficial for memory, various factors (e.g., lag and criterion level) moderate this benefit. Accordingly, the efficacy of retrieval practice depends on how students use retrieval practice during learning, which in turn depends on accurate metacognitive monitoring. The present experiments evaluated the extent to which judgments of learning (JOLs) made after correct responses are sensitive to factors (i.e., lag and criterion level) that moderate retrieval practice effects, as well as which cues influence JOLs under these conditions. Participants completed retrieval practice for word pairs with either short or long lags between practice trials until items were correctly recalled 1, 3, 6, or 9 times. After the criterion trial for an item, participants judged the likelihood of recalling that item on the final test 1 week later. JOLs showed correct directional sensitivity to criterion level, with both final test performance and JOLs increasing as criterion level increased. However, JOLs showed incorrect directional sensitivity to lag, with greater performance but lower JOLs for longer versus shorter lags. Additionally, results indicated that retrieval fluency and metacognitive beliefs about criterion level-but not lag-influenced JOLs. [ABSTRACT FROM AUTHOR]

In two experiments, we investigated the influence of repeated processing in the context of the generation effect. In both experiments, participants studied words once or twice. Once-studied words either were read or were generated from a definition. Twice-studied words were read both times, generated both times, or read once and generated once. Free recall was best (in order of decreasing performance) after generating twice, after generating plus reading, and finally after generating once; any generation was better than purely reading. Recognition showed a similar pattern, except that the benefit of generating twice was not as striking as in recall and that reading plus generating was just as effective as generating twice. The overall pattern of results is accounted for by a simple model in which a second encoding results in a reminding of the first encoding, and this additional encoding supports subsequent recollection. This reminding is, consequently, more effective in recall than in recognition, and it operates in accordance with the principles of transfer-appropriate processing. [ABSTRACT FROM AUTHOR]

Although much is known about the dynamics of memory search in the free recall task, relatively little is known about the factors related to recall termination. Reanalyzing individual trial data from 14 prior studies (1,079 participants in 28,015 trials) and defining termination as occurring when a final response is followed by a long nonresponse interval, we observed that termination probability increased throughout the recall period and that retrieval was more likely to terminate following an error than following a correct response. Among errors, termination probability was higher following prior-list intrusions and repetitions than following extralist intrusions. To verify that this pattern of results can be seen in a single study, we report a new experiment in which 80 participants contributed recall data from a total of 9,122 trials. This experiment replicated the pattern observed in the aggregate analysis of the prior studies. [ABSTRACT FROM AUTHOR]

Five experiments using the think/no-think (TNT) procedure investigated the effect of the no-think and substitute instructions on cued recall. In Experiment 1, when unrelated A-B paired associates were studied and cued for recall with A items, recall rates were reliably enhanced in the think condition and reliably impaired below baseline in the no-think condition. In Experiments 2 and 5, final recall was cued with B items, leading to reliably higher recall rates, as compared with baseline, in both the think and no-think conditions. This pattern indicates backward priming of no-think items. In Experiments 3 and 4, the no-think instruction was replaced with a thought substitution instruction, and participants were asked to think of another word instead of the studied one when they saw the no-think cued items. As in Experiments 1 and 2, the same amount of forgetting of B items was observed when A items were the cues, but in contrast to Experiment 2, there was no increase in the recall performance of A items when B items were the cues. These results suggest that not thinking of studied items or, alternatively, thinking of a substitute item to avoid a target item may involve different processes: the former featuring inhibition and the latter interference. [ABSTRACT FROM AUTHOR]

Older adults report a higher frequency of autobiographical memories for experiences that occurred between ages 15 and 30, as compared with other life periods. This reminiscence bump is evident for memories involving positive, but not negative, emotions. The cultural life script hypothesis proposes that people share knowledge for the types and timing of positive landmark events and that this script guides the memory search to the bump period. The present research examined whether a reminiscence bump would be evident when memory cues prompted recall of surprising and unexpected events. Older adults recalled positive and negative, surprising positive and surprising negative, or highly expected and highly unexpected events. Adults' memory distributions were compared with distributions of predicted life events generated by undergraduates. Reminiscence bumps were found not only for memories of positive and expected events, but also for memories of surprising and unexpected events. Implications for the life script account are discussed. [ABSTRACT FROM AUTHOR]

Although research has examined factors influencing understanding of informed consent in biomedical and forensic research, less is known about participants' attention to details in consent documents in psychological survey research. The present study used a randomized experimental design and found the majority of participants were unable to recall information from the consent form in both in-person and online formats. Participants were also relatively poor at recognizing important aspects of the consent form including risks to participants and confidentiality procedures. Memory effects and individual difference characteristics also appeared to influence recall and recognition of consent form information. [ABSTRACT FROM AUTHOR]

In two experiments with 6-month-old infants, we found that prior learning of an operant task (remembered for 2 weeks) mediated new learning of a modeling event (remembered for only 1 day) and increased its recall. Infants first learned to associate lever pressing with moving a toy train housed in a large box. One or 2 weeks later, three target actions were modeled on a hand puppet while the train box (a retrieval cue) was in view. Merely retrieving the train memory strengthened it, and simultaneously pairing its retrieved memory with the modeled actions potentiated their learning and recall. When paired 1 week later, deferred imitation increased from 1 day to 4 weeks; when paired 2 weeks later, it increased from 1 day to 6 weeks. The striking parallels between potentiated learning in infants and the prior knowledge effect in adults suggests that the prior knowledge effect originates in early infancy. [ABSTRACT FROM AUTHOR]

Objective: This study compared self-reported fatigue between 7-day and 4-week time frames and explored factors that affect patients' responses.Study Design and Setting: Two hundred and sixteen cancer patients completed either 7-day or 4-week version of the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F). Cochran-Mantel-Haenszel statistics and Cochran-Armitage trend tests were used to assess the association between time frame and item scores. Information function curves at both item and scale levels were depicted to evaluate the precision along the fatigue continuum. Differential item functioning (DIF) was used to examine the stability of the psychometric properties between time frames.Results: Time frame did not influence patients' item responses. Examination of information function curves at item level did not clearly favor either time frame. At the scale level, the 7-day time frame was slightly more precise overall than the 4-week time frame. No item demonstrated DIF between time frames. Neither gender nor fatigue severity had an impact on above results.Conclusion: This study suggests 7-day and 4-week time frame are equally appropriate in measuring fatigue, preference might be given to the more informative 7-day time frame. However, substantive considerations regarding the appropriate time frame should outweigh statistical ones. [ABSTRACT FROM AUTHOR]

Background: Due to the recurrent nature of low back pain (LBP), the traditional concepts of cure and recovery are challenged, and investigating the course rather than status at fixed time-points may help us understand prognosis as well as treatment effect. However, methods of frequent measuring still need development and validation. Therefore, this study aims to evaluate the agreement between continuous, quantitative self-assessment (weekly SMS) of the course of LBP over a one-year period and qualitatively derived retrospective patient self-appraisal of the same time-period. Methods: Participants were 32 subjects with LBP from primary care. The quantitative measures consisted of weekly SMS questions for one-year about pain intensity, days with LBP, and activity limitations for that week. For each subject, the weekly responses were graphed and categorized into categories based on intensity, variation and overall change patterns. Qualitative measures were based on semi-structured telephone interviews one-year after a consultation for LBP, where two coders independently categorized the self-appraisal of LBP course into the same predefined categories as the SMS-based trajectories. Furthermore, patients' perceived overall recovery was related to variation patterns from SMS track. Results: There was perfect agreement for 48% in the pain intensity domain, 53% in the variation domain and 63% in the change pattern domain. Most of the discordant cases were classified in neighboring categories with the majority relating to fluctuating patterns. The self-perceived overall recovery status seemed to be reflected quite well by the quantitative measures of pain intensity and days with pain in this study. Conclusion: This study shows that a real time quantitative measure (weekly SMS) and the patient's retrospective appraisal do not fundamentally differ in their reflection of the one-year course of LBP. As a first investigation into this area, these results are promising, as longitudinal quantitatively derived trajectories of LBP seem to reflect the lived experience of the patient to a large degree. Furthermore, the patient's ability to retrospectively recall their one-year course of LBP appears to be quite good. Future studies should focus on refining the categories of trajectories. [ABSTRACT FROM AUTHOR]