1. Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore
- Author
-
Padmapriya, N, Bernard, J Y, Liang, S, Loy, S L, Cai, S, Zhe, I S, Kwek, K, Godfrey, K M, Gluckman, P D, Saw, S M, Chong, Y.-S., Chan, J K Y, Müller-Riemenschneider, F, Sheppard, A, Chinnadurai, A, Neo Goh, A E, Rifkin-Graboi, A, Qiu, A, Biswas, A, Lee, B W, Broekman, B F P, Quah, B L, Shuter, B, Chng, C K, Ngo, C, Bong, C L, Henry, C J, Ing Chee, C Y, Daniel Goh, Y T, Fok, D, Yap, F, Heong Yeo, G S, Chen, H, van Bever, H P S, Magiati, I, Yun Wong, I B, Lau, I.Y.-M., Kapur, J, Richmond, J L, Holbrook, J D, Gooley, J J, Tan, K H, Niduvaje, K, Singh, L, Su, L L, Daniel, L M, Shek, L.P.-C., Fortier, M V, Hanson, M, Chong, M.F.-F., Rauff, M, Chua, M C, Meaney, M, Tint, M T, Karnani, N, Lek, N, Teoh, O H, Wong, P C, Agarwal, P, van Dam, R M, Rebello, S A, Chong, S C, Soh, S.-E., Lim, S B, Hsu, C.-Y.S., Rajadurai, V S, Stunkel, W, Han, W M, Pang, W W, Cheung, Y B, Chan, Y H, Lee, Y S, and APH - Mental Health
- Subjects
Blood Glucose ,endocrine system diseases ,Overweight ,Logistic regression ,600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit ,Gestational diabetes mellitus ,Cohort Studies ,0302 clinical medicine ,Risk Factors ,Pregnancy ,030212 general & internal medicine ,Singapore ,Obstetrics ,Obstetrics and Gynecology ,Fasting ,Postprandial Period ,3. Good health ,Gestational diabetes ,Postprandial ,Pregnancy Trimester, Second ,Gestation ,Female ,medicine.symptom ,Research Article ,Cohort study ,Adult ,medicine.medical_specialty ,030209 endocrinology & metabolism ,Sitting ,lcsh:Gynecology and obstetrics ,03 medical and health sciences ,Asian People ,medicine ,Humans ,Exercise ,lcsh:RG1-991 ,Gynecology ,business.industry ,Physical activity ,nutritional and metabolic diseases ,Glucose Tolerance Test ,medicine.disease ,Diabetes, Gestational ,Sedentary behavior ,Logistic Models ,Linear Models ,business ,Maternal glucose levels - Abstract
Background: Few studies have investigated physical activity (PA) and sedentary behavior (SB) in relation to fasting (FG) and 2-h postprandial plasma glucose (2hPG) levels and gestational diabetes mellitus (GDM); we investigated these associations among Asian pregnant women.Methods: As part of the Growing Up in Singapore Towards healthy Outcomes cohort study, PA and SB (sitting and television times) were assessed by interviewer-administered questionnaire. During 75 g oral glucose tolerance tests at 26–28 weeks' gestation we measured FG, 2hPG levels and GDM (FG ≥ 7.0 mmol/L and/or 2hPG ≥ 7.8 mmol/L). Associations were analysed by multiple linear and logistic regression.Results: Among the 1083 women studied, 18.6% had GDM. SB was not associated with FG, 2hPG and GDM. Higher categories of PA were associated with lower 2hPG and a lower likelihood of GDM (p-trend p = 0.020) and were less likely to have GDM [OR: 0.56 (0.32–0.98), p = 0.040]. Stratified analysis revealed no associations among under/normal-weight women, but significant associations among overweight/obese women; in those with BMI ≥23 kg/m2, sufficiently active and highly active women were less likely to have GDM [OR: 0.52, (0.29–0.93), p = 0.028, and OR: 0.34, (0.15–0.77), p = 0.010, respectively].Conclusion: Higher PA was associated with lower 2hPG levels and a lower prevalence of GDM, particularly in overweight/obese women. Further studies are warranted to confirm these findings, and to examine the effectiveness of PA promotion strategies for the prevention of gestational hyperglycemia.
- Published
- 2017