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Background: Electronic bibliographic databases are important tools when searching for medical information. The selected databases have an important effect on the potential results achieved. Studies about comparison of databases provide useful information to help determine which databases or set of databases are useful for a particular topic., Aims: The aim of this study is to examine the coverage and overlap of three commonly used databases in mental health research., Methods: We performed systematic database searches on four topics (ADHD prevalence, schizotypal personality, brain MRI studies in schizophrenia, recovery in schizophrenia) in three databases (PubMed, Web of Science and PsycINFO). We also studied the effect of publication year and language on database coverage., Results: PubMed was the most comprehensive database in ADHD (85% coverage of total results of the three databases) and MRI studies (71%), whereas PsycINFO was most effective in recovery (62%) and schizotypal personality (72%). The most comprehensive combination of two databases found 77-94% of the articles on the different topics. Publication year and language affected the coverage in some cases., Conclusions: When choosing databases, the extent of coverage and topic should be taken into account, as there is no single database that covers all information needs. In the case of interdisciplinary topics, the Web of Science or PsycINFO should be considered; PsycINFO should be included especially on topics related to psychology. The use of several relevant bibliographic databases, including others than those used here, is recommended.

We present bibliometric methods that can be utilized in evaluation processes of scientific work. In this paper, we present some practical clues using Finnish schizophrenia research as an example and comparing the research output of different institutions. Bibliometric data and indicators including publication counts, impact factors and received citations were used as tools for evaluating research performance in Finnish schizophrenia research. The articles and citations were searched from the Web of Science database. We used schizophrenia as a keyword and defined address Finland, and limited years to 1996-2005. When we analysed Finnish schizophrenia research, altogether 265 articles met our criteria. There were differences in impact factors and received citations between institutions. The number of annually published Finnish schizophrenia articles has tripled since the mid-1990s. International co-operation was common (43%). Bibliometric methods revealed differences between institutions, indicating that the methods can be applied in research evaluation. The coverage of databases as well as the precision of their search engines can be seen as limitations. Bibliometric methods offer a practical and impartial way to estimate publication profiles of researchers and research groups. According to our experience, these methods can be used as an evaluation instrument in research together with other methods, such as expert opinions and panels.

Background: Citation counts are often regarded as a measure of the utilization and contribution of published articles. The objective of this study is to assess whether statistical reporting and statistical errors in the analysis of the primary outcome are associated with the number of citations received. Methods: We evaluated all original research articles published in 1996 in four psychiatric journals. The statistical and reporting quality of each paper was assessed and the number of citations received up to 2005 was obtained from the Web of Science database. We then examined whether the number of citations was associated with the quality of the statistical analysis and reporting. Results: A total of 448 research papers were included in the citation analysis. Unclear or inadequate reporting of the research question and primary outcome were not statistically significantly associated with the citation counts. After adjusting for journal, extended description of statistical procedures had a positive effect on the number of citations received. Inappropriate statistical analysis did not affect the number of citations received. Adequate reporting of the primary research question, statistical methods and primary findings were all associated with the journal visibility and prestige. Conclusion: In this cohort of published research, measures of reporting quality and appropriate statistical analysis were not associated with the number of citations. The journal in which a study is published appears to be as important as the statistical reporting quality in ensuring dissemination of published medical science. [ABSTRACT FROM AUTHOR]

Development of psychiatric research methods requires systematic review of their status. This study describes the frequency with which various statistical research designs and methods are reported in general psychiatric journals. All original research articles in four psychiatric journals in 1996 were reviewed: The American Journal of Psychiatry (AJP), The Archives of General Psychiatry (AGP), The British Journal of Psychiatry (BJP) and the Nordic Journal of Psychiatry (NJP). Evaluation included 448 regular articles, which reported original research findings based on systematic collection and statistical analysis of research data. Aspects measured were research design, statistical methodology, description of procedures and presentation of results. Percentage frequencies of reported statistical procedures were compared between the journals. The policy of determining statistical significance was still the most generally used method of conducting research. Compared to earlier reviews, readers of psychiatric reports in 1996 more frequently encountered computer-dependent multivariate techniques. There were differences in the utilization and reporting of statistical procedures among the journals. The authors of psychiatric journals might apply these results in designing their psychiatric research to present intelligible and compact analysis combined with a high quality presentation technique, thus being in line with the policy and presentation of the leading psychiatric journals. [ABSTRACT FROM AUTHOR]

Background: Cell-in-cell structures (caused by cell cannibalistic activity) have been related to prognosis of many cancers. This is the first multi-institutional study to assess the prognostic impact of cell-in-cell structures in a large cohort of early oral tongue squamous cell carcinomas (OTSCC).Methods: A total of 308 cases from five Finnish University Hospitals and from the A.C. Camargo Cancer Center, São Paulo, Brazil, were included in this study. Cell-in-cell structures were evaluated on surgical postoperative sections that stained with hematoxylin and eosin staining.Results: We found that cell-in-cell structures associated with cancer-related mortality in univariable analysis with a hazard ratio (HR) of 2.99 (95%CI 1.52-5.88; P = 0.001). This association was confirmed in multivariable analysis (HR 2.22, 95%CI 1.12-4.44; P = 0.024). In addition, statistically significant associations were observed between the cell-in-cell structures and other adverse histopathologic characteristics including deep invasion (P <  0.001), high index of tumor budding (P = 0.007), worst pattern of invasion (P <  0.001), perineural invasion (P = 0.01), and stroma-rich pattern (P = 0.001).Conclusions: Our findings demonstrate a significant relationship between cell-in-cell formation and aggressive characteristics of early OTSCC. Cell-in-cell structures have a distinct impact as a novel prognostic indicator in early OTSCC and they can be easily assessed during routine pathology practice. [ABSTRACT FROM AUTHOR]