1. Predicting the handgrip strength across the age span: Cross-validating reference equations from the 2011 NIH toolbox norming study
- Author
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Inga Wang, Pei-Fen Chang, Chiung-ju Liu, Jay Kapellush, Mohammad Habibur Rahman, and Richard W. Bohannon
- Subjects
Male ,030506 rehabilitation ,Hand Strength ,National Health and Nutrition Examination Survey ,Mean squared error ,Correlation coefficient ,Rehabilitation ,Physical Therapy, Sports Therapy and Rehabilitation ,NIH Toolbox ,Hand ,Nutrition Surveys ,Confidence interval ,03 medical and health sciences ,Grip strength ,Cross-Sectional Studies ,0302 clinical medicine ,Reference Values ,Hand strength ,Statistics ,Humans ,Female ,0305 other medical science ,Independent data ,030217 neurology & neurosurgery ,Mathematics - Abstract
Study Design This is a cross-sectional observational study. Background Reference equations for describing hand-grip strength across the age span were derived from the 2011 NIH Toolbox norming study. Purpose The purpose of this study was to cross-validate reference equations by evaluating its predicting power on a separate, independent data set from the 2011-2014 National Health and Nutrition Examination Survey (NHANES) study Methods Observed hand-grip strength data from 13,676 noninstitutionalized participants were obtained from the NHANES study. Best values (best from 3 trials) and the mean values (averaged from 3 trials) were determined for each hand. Using the age (yr), height (m), and weight (kg), we computed predicted grip strength values for dominant and nondominant hands using the reference equations. For validation, three predictability measures: the correlation coefficient, residuals, and accuracy, were used along with the Bland-Altman plot. Results The predicted values highly correlated with observed values (r = 0.90, ICC = 0.89). In predicting best values, means (SD) of residuals were 1.41 (5.57) and 1.03 (5.44) kg for dominant and nondominant hands, respectively. In predicting mean values, means (SD) of residuals were −0.23 (5.42) and −0.54 (5.31) kg for dominant and nondominant hands, respectively. Root mean square error ranged from 4.10 (female's nondominant mean values) to 6.74 (male's dominant best values). About 5.56% fell outside of the 95% confidence interval of the prediction. Conclusions We acknowledged that the two studies' hand-grip protocols (NIH Toolbox, NHANES) were different. Results provided the preliminary predicting performance of the reference equations derived from the NIH Toolbox study.
- Published
- 2022