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Your search keyword '"Koch, W J"' showing total 35 results

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35 results on '"Koch, W J"'

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1. Genetic manipulation of beta-adrenergic signalling in heart failure.

2. Vascular beta-adrenergic receptor system is dysfunctional after myocardial infarction.

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3. Physiological induction of a beta-adrenergic receptor kinase inhibitor transgene preserves ss-adrenergic responsiveness in pressure-overload cardiac hypertrophy.

4. Vascular beta-adrenergic receptor adenylyl cyclase system in maturation and aging.

5. Adenovirus-mediated genetic manipulation of the myocardial beta-adrenergic signaling system in transplanted hearts.

6. Early effects of right ventricular volume overload on ventricular performance and beta-adrenergic signaling.

7. Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction.

9. Potential future therapies for heart failure: gene transfer of beta-adrenergic signaling components.

10. In vivo inhibition of elevated myocardial beta-adrenergic receptor kinase activity in hybrid transgenic mice restores normal beta-adrenergic signaling and function.

11. Defective beta-adrenergic receptor signaling precedes the development of dilated cardiomyopathy in transgenic mice with calsequestrin overexpression.

12. Molecular beta-adrenergic signaling abnormalities in failing rabbit hearts after infarction.

13. Molecular and functional mechanisms of right ventricular adaptation in chronic pulmonary hypertension.

14. Ontogeny of cardiac beta-adrenoceptor desensitization mechanisms: agonist treatment enhances receptor/G-protein transduction rather than eliciting uncoupling.

15. Bbeta-adrenergic receptor kinase-1 levels in catecholamine-induced myocardial hypertrophy: regulation by beta- but not alpha1-adrenergic stimulation.

16. The myocardial beta-adrenergic system in spontaneously hypertensive heart failure (SHHF) rats.

17. Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by beta-adrenergic receptor stimulation and blockade.

18. Myocardial overexpression of GRK3 in transgenic mice: evidence for in vivo selectivity of GRKs.

19. Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer.

20. Transgenic mice with cardiac overexpression of alpha1B-adrenergic receptors. In vivo alpha1-adrenergic receptor-mediated regulation of beta-adrenergic signaling.

21. Mechanism of beta-adrenergic receptor desensitization in cardiac hypertrophy is increased beta-adrenergic receptor kinase.

22. Potentiation of beta-adrenergic signaling by gene transfer.

23. Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency.

24. Myocardial beta-adrenergic receptor signaling in vivo: insights from transgenic mice.

25. Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.

26. Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase.

27. Prior beta blocker treatment decreases leukocyte responsiveness to injury

28. Myocardial adeno-associated virus serotype 6-βARKct gene therapy improves cardiac function and normalizes the neurohormonal axis in chronic heart failure

29. G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure

30. Elevated myocardial and lymphocyte GRK2 expression and activity in human heart failure

31. Exercise promotes angiogenesis and improves beta-adrenergic receptor signalling in the post-ischaemic failing rat heart

32. Exercise training and beta-blocker treatment ameliorate age-dependent impairment of beta-adrenergic receptor signaling and enhance cardiac responsiveness to adrenergic stimulation

33. Myocardial G protein-coupled receptor kinases: implications for heart failure therapy

34. Beta-adrenergic receptor kinase-1 levels in catecholamine-induced myocardial hypertrophy: regulation by beta- but not alpha1-adrenergic stimulation

35. Myocardial overexpression of GRK3 in transgenic mice: evidence for in vivo selectivity of GRKs