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Extraskeletal mesenchymal chondrosarcoma (ESMC) metastasizing to the pancreas in isolation is a rare entity. We present a case of a 30-year-old gentleman who underwent surgery for chondrosarcoma of the left temporal region (2017) and was detected to have a space-occupying a lesion of the pancreas 6 years post-surgery. Distal pancreatectomy was performed, and the histopathological examination revealed features suggestive of an extraskeletal mesenchymal chondrosarcoma. ESMC have a long latency period before presentation and these patients have a good survival following surgery. We present this case owing to its rarity.

Atrial fibrillation (AF) affects a significant proportion of older individuals, with prevalence rates of 3.8 ​% in those over 60 and 9.0 ​% in those over 80 years old, posing a considerable risk of stroke. Radiofrequency ablation (RFA) has emerged as a popular treatment option. However, RFA is not without risks, with esophageal injury being a notable complication, as illustrated by our case study of a 67-year-old patient who developed an atrial-esophageal fistula post-RFA. Timely diagnosis is imperative due to the rarity and severe consequences such as esophageal perforation. While treatment strategies remain somewhat uncertain, initial stenting has given way to surgical intervention for improved outcomes. Our study emphasizes the critical importance of vigilance, early identification, and a multidisciplinary approach in managing this challenging complication.

Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn’s disease (CD), is a global health problem with a worldwide increase in incidence. While previously it was more prevalent in Western countries, especially in North America and Europe, there has been a recent sizeable increase in the incidence of IBD in Asia. This article is a brief overview of the causative factors that contribute to this rise in IBD cases in Asian countries. There is a notable disparity between the Asian IBD population and the Western one in terms of age distribution and gender predilection, and genetic studies reveal both shared and unique susceptibility loci. Changes in environmental factors, including alterations in diet, hygiene, and lifestyle, are thought to play a key role in the epidemiological transition observed in Asia. It is crucial to comprehend how genetic predisposition interacts with environmental factors in order to understand the causes of IBD in the Asian population and develop precise interventions to alleviate its impact.

Abstract Background Inflammatory bowel disease (IBD) is increasingly diagnosed in South Asia. This survey by the Tamil Nadu Chapter of the Indian Society of Gastroenterology (TNISG) documents the demography, clinical profile, and therapeutic practices related to IBD in Tamil Nadu. Methods TNISG members from 32 institutions completed an online cross‐sectional questionnaire on IBD patients from March 2020 to January 2021. Results Of 1295 adult IBD patients, 654 had Crohn's disease (CD), 499 ulcerative colitis (UC), and 42 IBD‐unclassified (IBD‐U). CD and UC showed a unimodal age distribution. A total of 55% were graduates or postgraduates. A positive family history was noted in 30, other risk factors were uncommon. In CD, the pattern of involvement was ileocolonic (42.8%), ileal (34.7%), colonic (18.9%), and upper gastrointestinal (3.5%); while in UC, disease was characterized as extensive (44.9%), left‐sided (41.7%), or proctitis (13.4%). Perineal disease, perianal fistulae, and bowel obstruction were noted in 4.3, 14.0, and 23.5%, respectively, of CD. The most widely used drugs were mesalamine, azathioprine, and corticosteroids. Surgery was undertaken in 141 patients with CD and 23 patients with UC. Of the 138 patients with pediatric IBD (≤16 years), 23 were characterized as very early onset IBD (VEO‐IBD), 27 as early‐onset, and 88 as adolescent IBD. VEO‐IBD were more likely to have a positive family history of IBD and were more likely to have perineal disease and to have the IBD‐U phenotype. Among pediatric IBD patients, corticosteroids, mesalamine, and azathioprine were the most commonly used medications, while 25 pediatric patients received biologics. Conclusion This study provides important information on demography, clinical profile, and treatment practices of IBD in India.