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Your search keyword '"Julia Holzgruber"' showing total 2 results
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2 results on '"Julia Holzgruber"'

1. Feasibility and safety of using an automated decision support system for insulin therapy in the treatment of steroid‐induced hyperglycemia in patients with acute graft‐versus‐host disease: A randomized trial

Author

Felix Aberer, Julia K Mader, Julia Holzgruber, Christian Trummer, Verena Schwetz, Marlene Pandis, Peter N Pferschy, Hildegard Greinix, Norbert J Tripolt, Thomas R Pieber, Armin Zebisch, Heinz Sill, Albert Wölfler, and Harald Sourij

Subjects
Decision support system, Feasibility trial, Steroid‐induced hyperglycemia, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
Abstract

Abstract Steroid‐induced hyperglycemia (SIHG) has shown to independently increase the risk for mortality in patients with acute graft‐versus‐host disease, and it is still unclear whether SIHG might be a modifiable risk factor. Therefore, a feasibility trial was carried out aiming to evaluate the performance of a standardized decision support system (GlucoTab [GT]) for insulin therapy in patients with SIHG. A total of 10 hyperglycemic acute graft‐versus‐host disease patients were included and treated either with GT or standard of care during hospitalization. Follow‐up duration was 6 months. Comparing the GT versus standard of care group, 364 versus 1,020 glucose readings were available during a median of 41 days (interquartile range [IQR] 22–89) and 101 days (IQR 55–147) of hospitalization. The median overall glucose levels were 151 mg/dL (123–192) versus 162 mg/dL (IQR 138–193) for GT and standard of care, respectively (P

Published
2019
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2. Feasibility and safety of using an automated decision support system for insulin therapy in the treatment of steroid-induced hyperglycemia in patients with acute graft-versus-host disease: A randomized trial

Author

Harald Sourij, Felix Aberer, Marlene Pandis, Peter N. Pferschy, Heinz Sill, Verena Schwetz, Julia Holzgruber, Norbert J. Tripolt, Julia K. Mader, Armin Zebisch, Christian Trummer, Hildegard Greinix, Thomas R. Pieber, and Albert Wölfler

Subjects
Blood Glucose, Male, Epidemiology, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Graft vs Host Disease, Pilot Projects, Disease, Steroid‐induced hyperglycemia, law.invention, 0302 clinical medicine, Randomized controlled trial, law, Interquartile range, Medicine, Insulin, Decision support system, General Medicine, Articles, Middle Aged, Prognosis, Acute Disease, Female, Steroids, Safety, medicine.medical_specialty, Short Report, 030209 endocrinology & metabolism, Hypoglycemia, Diseases of the endocrine glands. Clinical endocrinology, 03 medical and health sciences, Feasibility trial, Internal medicine, Diabetes mellitus, Internal Medicine, Humans, Hypoglycemic Agents, In patient, Risk factor, Glycated Hemoglobin, business.industry, medicine.disease, RC648-665, Hyperglycemia, Feasibility Studies, business, Biomarkers, 030215 immunology, Follow-Up Studies
Abstract

Steroid‐induced hyperglycemia (SIHG) has shown to independently increase the risk for mortality in patients with acute graft‐versus‐host disease, and it is still unclear whether SIHG might be a modifiable risk factor. Therefore, a feasibility trial was carried out aiming to evaluate the performance of a standardized decision support system (GlucoTab [GT]) for insulin therapy in patients with SIHG. A total of 10 hyperglycemic acute graft‐versus‐host disease patients were included and treated either with GT or standard of care during hospitalization. Follow‐up duration was 6 months. Comparing the GT versus standard of care group, 364 versus 1,020 glucose readings were available during a median of 41 days (interquartile range [IQR] 22–89) and 101 days (IQR 55–147) of hospitalization. The median overall glucose levels were 151 mg/dL (123–192) versus 162 mg/dL (IQR 138–193) for GT and standard of care, respectively (P

Published
2018

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